Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients

Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients

Static echocardiographic variables did not reliably reflect the volume state as defined by estimates of mean systemic filling pressure. There was no statistical or clinically robust relationship between static echocardiographic... read more

Oxygen Escalation Therapy and Noninvasive Ventilation During COVID-19

Oxygen Escalation Therapy and Noninvasive Ventilation During COVID-19

We are in the midst of the COVID-19 pandemic. Many parts of the world have been ravaged by this virus, but disease severity varies significantly. There are several types of patients with COVID-19: those who have mild disease... read more

Allocating Ventilators in a Pandemic

Allocating Ventilators in a Pandemic

The COVID-19 pandemic has led to shortages of essential goods and services - from hand sanitizers to masks to beds to ventilators. Today, the healthcare system is facing the prospect of rationing medical goods and services. Mechanical... read more

Is COVID-19 ARDS?

Is COVID-19 ARDS?

Acute respiratory distress syndrome (ARDS) is a heterogeneous disease. It presents with a wide range of severity, varying degrees of hypoxemia and varying degrees of pulmonary mechanical impairment. Failure of hypoxemic vasoconstriction... read more

Optimizing Ventilator Use during the COVID-19 Pandemic

Optimizing Ventilator Use during the COVID-19 Pandemic

The COVID-19 outbreak is presenting unprecedented challenges to our health care system. According to our best projections, combined with information on the ground, the availability of precious medical resources will be limited... read more

Heart and Lung Damage for COVID-19 Patients

Heart and Lung Damage for COVID-19 Patients

While the focus of the COVID-19 pandemic has been on respiratory problems and securing enough ventilators, doctors on the front lines are grappling with a new medical mystery. In addition to lung damage, many COVID-19... read more

COVID-19 Patients Need Oxygen Not Pressure!

COVID-19 Patients Need Oxygen Not Pressure!

Critically ill coronavirus patients are being inadvertently harmed by the very same breathing machines being used to keep them alive, warning Dr. Cameron Kyle-Sidell from Maimonides Medical Center, NY. In a video posted... read more

Rationing of Critical Care and Ventilators in COVID19

Rationing of Critical Care and Ventilators in COVID19

In many hospitals ventilators have become a scarce or non-existent resource in the face of the COVID19 pandemic. We need a ethical structure to allocate ventilators and other scarce resources. ... read more

A Better Way of Connecting Multiple Patients to a Single Ventilator

A Better Way of Connecting Multiple Patients to a Single Ventilator

This differential multi-ventilation setup yields increased safety, monitoring and control for each connected patient. In an ideal world, no one treating patients with Acute Respiratory Distress Syndrome (ARDS) would have... read more

A Comparison of Albumin and Saline for Fluid Resuscitation in the ICU

A Comparison of Albumin and Saline for Fluid Resuscitation in the ICU

In this randomized trial, we found that the use of 4 percent albumin or normal saline for intravascular volume resuscitation in a heterogeneous population of patients in the ICU resulted in equivalent rates of death from... read more

1 Million Ventilators Project

1 Million Ventilators Project

We need to develop a strategic reserve of 1,000,000+ emergency ventilators ASAP. These don't need to be fancy medical ventilators, they just need to work. In a pandemic, the limited existing ventilator supply and stockpile... read more

Splitting Ventilators to Provide Titrated Support to a Large Group of Patients

Splitting Ventilators to Provide Titrated Support to a Large Group of Patients

COVID-19 can out-strip the number of mechanical ventilators available to us. This has led to interest in using a single ventilator to support multiple patients. This post will review the theory and evidence regarding this... read more

Lung Ultrasonography Features of COVID-19 Pneumonia

Lung Ultrasonography Features of COVID-19 Pneumonia

As lung abnormalities may develop before clinical manifestations and nucleic acid detection, experts have recommended early chest computerized tomography (CT) for screening suspected patients. The high contagiousness... read more

COVID-19 Airway Management – The Role of Simulation

COVID-19 Airway Management – The Role of Simulation

Health services around the world are faced with the challenge of preparing for the impact of COVID-19 on their communities as we all prepare for a potential global pandemic. I see a great role for simulation in process... read more

Decrease Delirium in Older ICU Adults Using Music

Decrease Delirium in Older ICU Adults Using Music

Researchers from the Regenstrief Institute and Mayo Clinic are leading the first study to test whether exposure to music can decrease delirium in older adults who are receiving mechanical ventilation in the Intensive Care... read more

ICU Risk Factors and Outcomes for Each Delirium Subtype

ICU Risk Factors and Outcomes for Each Delirium Subtype

Although included studies reported on many subtype-specific risk factors (hypoactive, hyperactive) and outcomes, heterogeneity in reporting and methodological quality limited the generalizability of the results and the evidence... read more

Respiratory Support for Patients with COVID-19 Infection

Respiratory Support for Patients with COVID-19 Infection

Coronavirus disease 2019 (COVID-19) has affected more than 50 countries so far this year. Xiaobo Yang and colleagues described in their single-centered, retrospective, observational study that 52 of 710 patients with confirmed... read more