Tag: oxygenation
Pediatric Extracorporeal Cardiopulmonary Resuscitation ELSO Guidelines
Survival rates with good neurologic outcomes following conventional cardiopulmonary resuscitation (CPR) for cardiopulmonary arrest, either in the in-hospital (IH) or out-of-hospital settings, have improved but remain poor... read more
An Index Combining Respiratory Rate and Oxygenation to Predict Outcome of Nasal High-Flow Therapy
In patients with pneumonia with acute respiratory failure treated with high-flow nasal cannula (HFNC), ROX is an index that can help identify those patients with low and those with high risk for intubation. This was a... read more
COVID-19 Awake Proning – All Hype?
In this prospective meta-analysis of observational studies of patients with acute hypoxemic respiratory failure due to COVID-19, APP did not result in lower intubation or mortality rates, despite reported improvements in... read more
Nebulised heparin for patients with or at risk of ARDS
In patients with or at risk of acute respiratory distress syndrome (ARDS), nebulised heparin did not improve self-reported performance of daily physical activities, but was well tolerated and exploratory outcomes suggest... read more
Janssen Investigational COVID-19 Vaccine
An investigational COVID-19 vaccine developed by Janssen Pharmaceuticals appears to be safe and effective at preventing moderate and severe COVID-19 in adults, according to an interim analysis of Phase 3 clinical data conducted... read more
Timing, Outcome, and Risk Factors of Intracranial Hemorrhage in ARDS Patients During VV-ECMO
Intracranial hemorrhage occurs early during venovenous extracorporeal membrane oxygenation (VV-ECMO) and is a determinant for 60-day mortality. Appropriate adjustment of identified modifiable risk factors might lower... read more
Apnoeic Oxygenation for Emergency Anaesthesia of Pre-hospital Trauma Patients
Apnoeic oxygenation did not influence peri-intubation oxygen saturations, but it did reduce the frequency and duration of hypoxia in the post-intubation period. Given that apnoeic oxygenation is a simple low-cost intervention... read more
Risk Factors of Ischemic and Hemorrhagic Strokes During Venovenous ECMO
Among venovenous extracorporeal membrane oxygenation patients in the Extracorporeal Life Support Organization registry, approximately 5% had acute brain injury. Mortality rates increased two-fold when ischemic or hemorrhagic... read more
A Novel Negative Pressure-Flow Waveform to Ventilate Lungs for Normothermic Ex Vivo Lung Perfusion
Ex vivo lung perfusion (EVLP) is increasingly used to treat and assess lungs before transplant. Minimizing ventilator induced lung injury (VILI) during EVLP is an important clinical need, and negative pressure ventilation... read more
Venoarterial ECMO in Elderly Patients with Refractory Cardiogenic Shock
The clinical utilization of extracorporeal membrane oxygenation (ECMO) has seen remarkable expansion since its inception in the early 1970s, including a period of exponential growth in the United States. Venoarterial... read more
Medical officials use new tool for COVID patients
The Barren-Metcalfe County Emergency Medical Service will soon implement a new medical device that will benefit COVID-19 patients as well as emergency medical personnel. The medical device, the Sea-Long helmet, is a clear,... read more
Extracorporeal Membrane Oxygenation for COVID-19
The coronavirus disease 2019 (COVID-19) pandemic has placed extraordinary strain on global healthcare systems. Use of extracorporeal membrane oxygenation (ECMO) for patients with severe respiratory or cardiac failure attributed... read more
Pulse Oximeter Devices Have Higher Error Rate in Black Patients
A study showed that the devices, which measure oxygen levels in the blood, were three times more likely to give misleading readings among African-American patients. Pulse oximeters are one of the most commonly used tools... read more
Improved Oxygenation After Prone Positioning May Be a Predictor of Survival in Patients With ARDS
We found a significant difference in the Pao2:Fio2 ratio after the first prone positioning between ICU survivors and nonsurvivors. The improvement in oxygenation after the first prone positioning was a significant predictor... read more
ECG Pointers: Cocaine and ST Elevation
This ECG comes from a 21-year-old male with a history of cocaine abuse. When I say ‘history’, I mean that he just snorted some cocaine and now he has chest pain. He looks uncomfortable and sweaty, and keeps... read more
The Feasibility of Studying Metabolites in PICU MODS
Metabolites are generated from critical biological functions and metabolism. This pediatric study reviewed plasma metabolites in patients suffering from multi-organ dysfunction syndrome (MODS) in the pediatric intensive care... read more
Myorelaxants in ARDS patients
Neuromuscular blocking agents (NMBAs) inhibit patient-initiated active breath and the risk of high tidal volumes and consequent high transpulmonary pressure swings, and minimize patient/ ventilator asynchrony in acute respiratory... read more
Airway closure, more harmful than atelectasis in intensive care?
Since the mid-1980s, atelectasis has been demonstrated during anesthesia in lung healthy subjects and in intensive care patients suffering from acute respiratory failure and requiring ventilator support. In the latter... read more
High Plasma Levels Linked to Severe ARDS in Children with Respiratory Failure
Elevated surfactant protein D levels are associated with severe acute respiratory distress syndrome and poor outcomes in children with acute respiratory failure, according to results published in Chest. Elevated surfactant... read more
Brain Injury Is More Common in vv-ECMO Than VA-ECMO
Brain injury was more common in venoarterial extracorporeal membrane oxygenation (VA-ECMO) compared with venovenous extracorporeal membrane oxygenation (vv-ECMO). While ischemic brain injury was more common in venoarterial... read more
Extracorporeal Cytokine Adsorption as an Alternative to Pharmacological Inhibition of IL-6 in COVID-19
With great interest we read the article by Convertino et al. discussing potential treatment targets for pharmacological immunomodulation in coronavirus disease 2019 (COVID-19) with acute respiratory distress syndrome (ARDS).... read more
