Tag: pneumonia
Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients
Humanigen, the clinical stage biopharmaceutical company focused on preventing and treating cytokine storm, has reported positive data from the first clinical use of lenzilumab, its humaneered anti-human granulocyte macrophage-colony... read more
Remdesivir 5-day vs. 10-day Trial Raises Some Red Flags?
Gilead's first Randomized Controlled Trial on remdesivir was just published, and it's very interesting. This is a trial designed, monitored, and written by Gilead. In some ways, the design of the trial and its missing parts... read more
A Mass Casualty In Slow Motion: Emergency Medicine During the COVID-19 Surge in New York City
The first time I really took notice of coronavirus was when a few providers started wearing masks during their shifts. This was in mid-February when the virus was a Wuhan problem, and we were screening people with travel... read more
Can COVID-19 Cause Sepsis? Coronavirus Disease and Sepsis Relationship
On January 30th, the World Health Organization declared the 2019 Novel Coronavirus (SARS-CoV-2) a global health emergency, declaring it an "unprecedented outbreak." While the fears of a COVID-19 pandemic are legitimate,... read more
In the Fight to Treat Coronavirus, Your Lungs Are a Battlefield
Ventilators have become the single most important piece of medical equipment for critically ill coronavirus patients whose damaged lungs prevent them from getting enough oxygen to vital organs. The machines work by forcing... read more
Awake Proning for COVID-19
Prone positioning improves oxygenation in spontaneous breathing nonintubated patients with hypoxemic acute respiratory failure: A retrospective study. This is a retrospective case series describing 15 non-intubated patients... read more
Rapid Development of an Inactivated Vaccine Candidate for COVID-19
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are currently no SARS-CoV-2-specific... read more
Supine Body Position As a Risk Factor for Nosocomial Pneumonia in Mechanically Ventilated Patients
The frequency of clinically suspected nosocomial pneumonia was lower in the semirecumbent group than in the supine group. This was also true for microbiologically confirmed pneumonia. Supine body position were independent... read more
What’s Working for COVID-19 Patients in the Epicenter
Our large tertiary care ED in Queens, NY, usually sees more than 100,000 adults a year. As we write this, we have 850 COVID-19-likely or -positive patients (several hundred above our bed capacity just one month ago), more... read more
Nationwide System to Centralize Decisions Around ECMO Use for Severe COVID-19 Pneumonia in Japan
The novel coronavirus disease 2019 (COVID-19) is spreading in Japan. The number of patients who need extracorporeal membrane oxygenation (ECMO) is expected to increase; however, the clinical characteristics of the patients... read more
Here’s a Lifesaving COVID-19 Test That Costs Almost Nothing
The New York Times ran a fascinating op-ed on Monday, and I’m surprised that it hasn’t gotten more attention. Here’s the nickel summary: a hotshot ER doctor volunteered to spend time at Bellevue Hospital in Manhattan... read more
Patient Self-proning with HFNC Improves Oxygenation in COVID-19 Pneumonia
A high-flow nasal cannula (HFNC) is commonly used in the management of hypoxic respiratory failure, and is associated with more ventilator-free days and lower mortality compared with standard oxygen therapy or non-invasive... read more
First Case of COVID-19 Complicated With Fulminant Myocarditis
COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure. This is the first report of COVID-19 complicated with fulminant myocarditis. The mechanism of cardiac pathology caused by COVID-19... read more
COVID-19 Pneumonia: ARDS or Not?
Even though it can meet the ARDS Berlin definition, the COVID-19 pneumonia is a specific disease with peculiar phenotypes. Its main characteristic is the dissociation between the severity of the hypoxemia and the maintenance... read more
Small Compact Resuscitation Device Safely Used on Patient with COVID-19
A small compact and portable resuscitation ventilation device built by PRIMEDIC OXYLATOR, was safely used to treat a patient with COVID-19 pneumonia in the intensive care unit (ICU). The Oxylator from Primedic is a combination... read more
How COVID-19 Causes ARDS
As the COVID-19 outbreak continues, we're learning more about the disease, what it does to the body and the damage it causes. Although many people with COVID-19 have no symptoms or only mild symptoms, a subset of patients... read more
Risk Factors Associated With ARDS and Death in Patients With COVID-19 Pneumonia in China
Older age was associated with greater risk of development of Acute Respiratory Distress Syndrome (ARDS) and death likely owing to less rigorous immune response. Although high fever was associated with the development of ARDS,... read more
