Filling the Gap: Non-Drug Interventions After Critical Care

A comprehensive scoping review sought to summarize the current landscape of non-pharmacological interventions aimed at improving patient outcomes following discharge from critical care. From over 41,000 reports screened,... read more

Move Early, Recover Faster: Early Mobilization Slashes ICU Stays Without Adding Risk

An updated systematic review and meta-analysis of 16 high-quality randomized trials (2,385 ICU patients) delivers a clear verdict: starting mobilization within 72 hours of admission is not only safe but powerfully effective.... read more

Neuro-ICU Admissions: Lower Mortality, Higher Disability Risk

This large-scale retrospective cohort study analyzed the clinical and epidemiological profiles of over 62,000 Intensive Care Unit (ICU) patients across seven hospitals, finding that the 10,884 patients admitted for primary... read more

The Paradox of Recovery: Faster APACHE II Decline Does Not Guarantee Better Trauma Outcomes

This study investigated a novel metric, APACHE/m (the average daily decrease in the APACHE II score), to determine if a faster rate of physiological improvement predicts better post-ICU outcomes in trauma patients. While... read more

Improving Critical Care Survivorship: A Guide to Prevention, Recovery, and Reintegration

This book, just published, provides a comprehensive overview of improving critical care survivorship. Comprised of four sections, the text presents interventions that can be used to improve patient outcomes and reduce the... read more

Improving Critical Care Survivorship: A Guide to Prevention, Recovery, and Reintegration

Thirst Management in Orotracheally Intubated and Mechanically Ventilated Patients

Symptom Management Theory (SMT)-based thirst management is an effective strategy. The 5 mL cold water spray method significantly reduces thirst intensity and distress in mechanically ventilated patients under fasting and... read more

Peripheral and Respiratory Muscle Weakness and Functional Impairments in ICU Patients

This study demonstrated that patients discharged from ICU in this resource-constrained setting presented with peripheral and respiratory muscle weakness at unit discharge. Muscle weakness occurred despite a short ICU... read more

Favorable Outcomes When Using Prolonged CPR Combined with ECPR

Extracorporeal CPR (ECPR) combined with continuous renal replacement therapy (CRRT) successfully rescues a patient who experienced sudden cardiac arrest for 152 minutes. ECPR is an effective and advanced form of extracorporeal... read more

Multidisciplinary Collaborative Bundled Care Improves Outcomes in ICU Patients with Endotracheal Intubation

Multidisciplinary analgesic and sedative bundled care has demonstrated the potential to decrease restraint use in patients undergoing endotracheal intubation and mechanical ventilation, reduce the need for analgesic and sedative... read more

Trauma Medical Home: New Coordinated Care Model for Injured Older Adults

Older adults who suffer serious injuries from a fall or a motor vehicle accident often have impaired long-term functioning and diminished quality of life. A new study, published in JAMA Surgery by researcher-clinicians... read more

Early Calorie and Protein Restriction Associated with Faster Recovery in Ventilated Patients

Compared with standard calorie and protein targets, early calorie and protein restriction did not decrease mortality but was associated with faster recovery and fewer complications. Of 3,044 patients randomly assigned... read more

6 Days Higher-Dose Ivermectin vs. Placebo on Time to Sustained Recovery in COVID-19 Outpatients

Among a largely vaccinated outpatient population with mild to moderate COVID-19, treatment with ivermectin, with a targeted maximum dose of 600 μg/kg daily for 6 days, compared with placebo was not shown to improve time... read more

Molnupiravir Improves Recovery Time in COVID-19 Patients at High Risk of Severe Outcomes

This analysis of a large randomized trial involving people who are at high risk of experiencing severe outcomes from COVID-19 and who had been vaccinated against SARS-CoV-2 infection found that adding molnupiravir to usual... read more

House Officer’s Guide to ICU Care

Your Must-Have Guide for Navigating the ICU The House Officer's Guide to ICU Care is an eminently practical handbook for junior house officers, medical students, PAs, and nurses that offers nuts-and-bolts guidelines for optimal... read more

House Officer’s Guide to ICU Care

Sedation Management Evolution in the ICU

This paper provided an overview of how ICU sedation practices have evolved over the last 20 years. Contemporary ICU sedation practices include light levels of sedation, SAT, and use of non-benzodiazepines. The current... read more

Mental Health Morbidity Among Caregivers

While much of the research on post-ICU mental health morbidity has focused upon the survivors themselves, emerging data shows that caregivers of ICU patients are similarly impacted. The collective sequelae experienced... read more

Multiple Organ Dysfunction in Older Major Trauma Critical Care Patients

Frailty rather than chronological age appears to drive multiple organ dysfunction syndrome (MODS) development, recovery, and outcome in older cohorts. Early identification of frailty after trauma may help to predict MODS... read more

Subclavian vs. Femoral Arterial Cannulations During ECMO

During peripheral extracorporeal veno-arterial membrane oxygenation (VA-ECMO) support, subclavian arterial cannulation provides, in comparison to femoral arterial cannulation, an anterograde flow which may prevent from left... read more

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

This book is a practical manual for anti-COVID-19. It is not only with the reference to the result of modern medical science, patients' situation, but also take the deployment of medical resources into consideration. Content... read more

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients

Among hospitalised COVID-19 patients needing oxygen therapy, high dose of dexamethasone reduced clinical worsening within 11 days after randomisation as compared with low dose of dexamethasone. Further studies are necessary... read more

High-Flow Oxygen Therapy vs. Conventional Oxygen Therapy on Invasive Mechanical Ventilation in COVID-19 Patients

Among patients with severe COVID-19, use of high-flow oxygen through a nasal cannula significantly decreased need for mechanical ventilation support and time to clinical recovery compared with conventional low-flow oxygen... read more

Recovery, Rehabilitation and Follow-up Services After Critical Illness

Overall, these data demonstrate a proliferation of recovery, follow-up and rehabilitation services for critically ill adults in the past decade across the UK, although service gaps remain suggesting further work is required... read more