Left Ventricular Wall Findings in Non-electrocardiography-gated CE-CT After ECPR

Left Ventricular Wall Findings in Non-electrocardiography-gated CE-CT After ECPR

Few studies have reported left ventricular wall findings in contrast-enhanced computed tomography (CE-CT) after extracorporeal cardiopulmonary resuscitation (ECPR). This study examined left ventricular wall CE-CT findings... read more

Long-term Cognitive Impairment After ARDS

Long-term Cognitive Impairment After ARDS

Reducing the practical burden of cognitive recovery following critical illness depends crucially on understanding the links between brain injury and lung injury. New deficits in learning and memory, and new development... read more

Pilot Randomized Trial of a Recovery Navigator Program for Survivors of Critical Illness With Problematic Alcohol Use

Pilot Randomized Trial of a Recovery Navigator Program for Survivors of Critical Illness With Problematic Alcohol Use

A Recovery Navigator intervention was feasible and acceptable for delivering high-fidelity brief interventions to ICU patients. Changes in alcohol-related problems with motivational interviewing and shared decision-making... read more

SSEP Retains its Value as Predictor of Poor Outcome Following Cardiac Arrest in the Era of Therapeutic Hypothermia

SSEP Retains its Value as Predictor of Poor Outcome Following Cardiac Arrest in the Era of Therapeutic Hypothermia

The absence of the somatosensory evoked potential (SSEP) N20 cortical wave remains one of the most reliable early prognostic tools for identifying unfavorable neurologic outcome in the evaluation of patients with severe anoxic-ischemic... read more

How To Prevent Brain-Sapping Delirium In The ICU

How To Prevent Brain-Sapping Delirium In The ICU

After an overwhelming infection sent O'Burke into five-organ failure, he also developed ICU delirium, perhaps related to heavy sedation. An ICU protocol developed at Vanderbilt University Medical Center found that getting... read more

Should fecal microbial transplantation be used in the ICU?

Should fecal microbial transplantation be used in the ICU?

FMT has become an attractive option to mitigate multiple organ dysfunction in the ICU. This article discusses the physiology, rationale, early experience, and expectations for such therapy in the critically ill patient. The... read more

The Effect of Early Mobilization in Critically Ill Patients

The Effect of Early Mobilization in Critically Ill Patients

This study indicated that early mobilization was effective in preventing the occurrence of ICU-AW, shortening the length of ICU and hospital stay, and improving the functional mobility. However, it had no effect on the ICU... read more

Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus

Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus

Patients with refractory status epilepticus (RSE) treated with continuous intravenous anesthetic drugs (cIVADs) may benefit from early initiation of such therapy. When cIVADs are applied in RSE, prescribing them early... read more

Early Detection and Monitoring of Cerebral Ischemia Using Calcium-Responsive MRI Probes

Early Detection and Monitoring of Cerebral Ischemia Using Calcium-Responsive MRI Probes

The duration of cerebral ischemia is a key factor in determining the severity of brain damage and the course of action. Thus, an accurate and timely observation of the ischemic process is highly critical. Here we present... read more

Improving Outcomes for ICU Survivors

Improving Outcomes for ICU Survivors

In response to the many challenges faced by ICU survivors today, there has been an increasing need to relieve this burden. Despite that many clinical trials have been implemented to find new strategies, post-intensive care... read more

Key Enablers and Barriers for Improving ICU Outcomes

Key Enablers and Barriers for Improving ICU Outcomes

Several enablers and barriers to implementing ICU follow-up clinics and peer support groups should be taken into account and leveraged to improve ICU recovery. Among the most important enablers are motivated clinician leaders... read more

Sedation and Analgesia Impact On Long-term Cognitive Dysfunction in Critical Care Survivors

Sedation and Analgesia Impact On Long-term Cognitive Dysfunction in Critical Care Survivors

Deep sedation during stay in the Intensive Care Unit (ICU) may have deleterious effects upon the clinical and cognitive outcomes of critically ill patients undergoing mechanical ventilation. Over the last decade a vast... read more

Physical Function Impairment in Survivors of Critical Illness in an ICU Recovery Clinic

Physical Function Impairment in Survivors of Critical Illness in an ICU Recovery Clinic

Physical function measurement in a recovery clinic is feasible and may inform subsequent morbidity and mortality. 36 patients were seen in clinic from July 2014 to June 2015; the median SPPB score was 5 (IQR 5). The... read more

Adjunctive Corticosteroid Treatment in Septic Shock

Adjunctive Corticosteroid Treatment in Septic Shock

Interest in the role of the adrenal cortex in the recovery from an infection dates back nearly 100 yr. More than six decades of research on the role of corticosteroid supplementation as an adjunctive treatment for sepsis... read more

Derivation and Validation of Plasma Endostatin for Predicting Renal Recovery from AKI

Derivation and Validation of Plasma Endostatin for Predicting Renal Recovery from AKI

Plasma endostatin shows a useful value for predicting failure to recover from acute kidney injury (AKI). The predictive ability can be greatly improved when endostatin is combined with the Sequential Organ Failure Assessment... read more

Randomized Clinical Trial of an ICU Recovery Pilot Program for Survivors of Critical Illness

Randomized Clinical Trial of an ICU Recovery Pilot Program for Survivors of Critical Illness

This randomized pilot trial found that a multidisciplinary ICU recovery program could deliver more interventions for post ICU recovery than usual care. The finding of longer time-to-readmission with an ICU recovery program... read more

Amount of Muscle Mass During ICU Admission May Be Linked to Survival

Amount of Muscle Mass During ICU Admission May Be Linked to Survival

In the study cohort, ICU admission pectoralis muscle area (PMA) was associated with survival during and following critical illness; it was unable to predict regaining an independent lifestyle following discharge. ICU admission... read more