Multiple Electrolytes Solution vs. Saline as Bolus Fluid for Pediatric Septic Shock Resuscitation

Among children presenting with septic shock, fluid resuscitation with MES (balanced crystalloid) as compared with 0.9% saline resulted in a significantly lower incidence of new and/or progressive AKI during the first 7 days... read more

Correlation of Common Carotid Artery Blood Flow Parameters With TTE-CO for Assessing Fluid Responsiveness After PLR Test in Critically Ill Patients

The passive leg raising (PLR) test is a simple, non-invasive method of knowing fluid responsiveness by acting as an internal-fluid challenge. The PLR test coupled with a non-invasive assessment of stroke volume would be the... read more

Fluid Responsiveness Evaluation with Integrated Ultrasonographic Approach

In a group of non-ventilated patients, who had already undergone the initial resuscitation, we demonstrated that the evaluation of the fluid responsiveness (FR) based on echocardiography and lung ultrasound increased the... read more

Traumatic Hemorrhage and Chain of Survival

Trauma is the number one cause of death among Americans between the ages of 1 and 46 years, costing more than $670 billion a year. Following death related to central nervous system injury, hemorrhage accounts for the majority... read more

Resuscitative TEE

The use of ED resuscitative transesophageal echocardiography (TEE) is a practical modality that provides useful diagnostic and therapeutic information for critically ill patients in the emergency department, with an excellent... read more

Duration of Device-Based Fever Prevention After Cardiac Arrest

While fever prevention for 72 hours after cardiac arrest has been endorsed by international guidelines since 2005, there is a lack of randomized control trial (RCT) generated data supporting this after the initial 24 hours... read more

Are Two Shocks Better Than One?

Overall, the trial conducted by Cheskes et al contributes meaningfully to our understanding of the use of alternative defibrillation strategies for refractory ventricular fibrillation before widespread incorporation of double... read more

Diastolic Shock Index and Septic Shock Outcome

Early recognition and resuscitation of patients in septic shock are critical skills for an emergency medicine physician. Many clinical decision-making tools have been developed and validated in their use to identify and... read more

Prehospital IV Fluid Management in Severely Injured Trauma Patients

Weak, primarily observational evidence suggests that standard fluid resuscitation has no significant mortality benefit over restricting/withholding IV fluids in the context of severe/hypotensive trauma. This review adds... read more

Family Presence During Cardiac Arrest Resuscitation

This systematic review identified four key findings. Firstly, there was a lack of high-quality evidence on the impact of family presence during resuscitation on patient outcomes. Secondly, family members had varied... read more

Evaluation of abdominal compression-decompression combined with chest compression CPR performed by a new device

Compression–decompression cardiopulmonary resuscitation (CO-CPR) was more beneficial than standard cardiopulmonary resuscitation (STD-CPR) in terms of survival benefits in patients who have suffered out-of-hospital cardiac... read more

Is Continuous Intra-abdominal Pressure Ready For Prime Time?

Abdominal contents are primarily fluid in character so that pressure within this compartment follows Pascal's hydrostatic law. Intra-abdominal pressure (IAP) is the steady state pressure within the abdominal cavity and changes... read more

Improving Outcomes in Patients with Difficult Airways

Evidence indicates that the airway community has successfully conquered the anatomically difficult airway, as these patients are managed safely with a low incidence of morbidity and mortality. In contrast, the literature... read more

Advanced Bleeding Control in Combat Casualty Care

Consensus was reached on the contents of a standard bleeding control toolbox, where it should be available, providers and training requirements, international registries and guidelines, and potential indications for REBOA... read more

Expert Consensus on PeRcutaneous Cannulation for ECPR

We present inclusion and exclusion criteria and a comprehensive, detailed, generalizable list of best practices for extracorporeal cardiopulmonary resuscitation (ECPR) initiation following refractory out-of-hospital cardiac... read more

CRT-targeted Fluid Resuscitation vs. Lactate-targeted in Septic Shock

Capillary refill time (CRT)-targeted fluid resuscitation in septic shock was not superior to a lactate-targeted one on early fluid administration or fluid balances. However, it was associated with comparable effects on regional... read more

Critically Unwell Child Intubation in the ED

Intubation in the pediatric emergency department is scary stuff. For critically ill children who require intubation, it is rarely practiced outside of the critical care unit. With the centralization of services there are... read more

Damage Control in Trauma Care: An Evolving Comprehensive Team Approach

This book describes current, evidence-based guidelines for damage control interventions across the field of trauma care with the aim of enabling clinicians to apply them to best effect in daily clinical practice. Emphasis... read more

Damage Control in Trauma Care: An Evolving Comprehensive Team Approach

Pulse Oximetry Waveform: A Non-invasive Physiological Predictor for the ROSC During CPR

Pulse oximetry plethysmography (POP) may be a novel and effective method for predicting return of spontaneous circulation (ROSC) during resuscitation, with a prognostic value similar to ETCO2 at early stage. 150 out-of-hospital... read more

Vasopressor Choice and Timing in Vasodilatory Shock

Vasodilatory shock is the most common form of circulatory shock encountered in patients admitted to the intensive care unit (ICU). Sepsis is the predominant etiology, but other causes of vasodilatory shock include postoperative... read more

Acute Kidney Injury Related to Intoxication From Synthetic Cannabis

Acute kidney injury (AKI) occurs infrequently in young patients and often raises concern for irreversible or deadly etiologies. However, AKI related to synthetic marijuana, colloquially known as K2, is an increasingly common... read more

Epinephrine vs. Norepinephrine in Cardiac Arrest Patients with Post-resuscitation Shock

Among patients with post-resuscitation shock after out-of-hospital cardiac arrest, use of epinephrine was associated with higher all-cause and cardiovascular-specific mortality, compared with norepinephrine infusion. Until... read more