The Surviving Sepsis Campaign: Fluid Resuscitation and Vasopressor Therapy Research Priorities in Adult Patients

The Surviving Sepsis Campaign: Fluid Resuscitation and Vasopressor Therapy Research Priorities in Adult Patients

In the second of a series of manuscripts subsequent to the original article, members with expertise in the subjects expound upon the three identified priorities related to fluid resuscitation and vasopressor therapies. This... read more

Increase in PI during PLR detects a positive response of the PLR test

Increase in PI during PLR detects a positive response of the PLR test

An increase in perfusion index (PI) during passive leg raising (PLR) by 9% accurately detects a positive response of the PLR test. Three patients were excluded because the plethysmography signal was absent and 3 other... read more

Pediatric Extracorporeal Cardiopulmonary Resuscitation ELSO Guidelines

Pediatric Extracorporeal Cardiopulmonary Resuscitation ELSO Guidelines

Survival rates with good neurologic outcomes following conventional cardiopulmonary resuscitation (CPR) for cardiopulmonary arrest, either in the in-hospital (IH) or out-of-hospital settings, have improved but remain poor... read more

EROCA: Results of a Randomized Feasibility Trial of Expedited Out-of-Hospital Transport

EROCA: Results of a Randomized Feasibility Trial of Expedited Out-of-Hospital Transport

Outcomes of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest depend on time to therapy initiation. We hypothesize that it would be feasible to select refractory out-of-hospital cardiac... read more

Association between the BMI and outcomes of patients resuscitated from OHCA

Association between the BMI and outcomes of patients resuscitated from OHCA

The body mass index (BMI) was not independently associated with favourable neurologic and survival outcomes of patients surviving from out-of-hospital cardiac arrest (OHCA). Nine hospitals were enrolled; finally, 605 patients... read more

Overcoming Enteral Nutrition Delivery Challenges in Critical Care

Overcoming Enteral Nutrition Delivery Challenges in Critical Care

It is the essential implementation of this new evidence occurs to overcome real and perceived EN challenges. This data should lead to increased standardization/protocolization of ICU nutrition therapy to ensure personalized... read more

The Impact of Defibrillation on Aerosol Generation During CPR

The Impact of Defibrillation on Aerosol Generation During CPR

Chest compressions alone did not cause significant aerosol generation in this swine model. However, increased aerosol generation was detected during chest compression immediately following defibrillation. Additional research... read more

Effect of Out-of-Hospital Sodium Nitrite on Survival to Hospital Admission After Cardiac Arrest

Effect of Out-of-Hospital Sodium Nitrite on Survival to Hospital Admission After Cardiac Arrest

Among patients with out-of-hospital cardiac arrest, administration of sodium nitrite, compared with placebo, did not significantly improve survival to hospital admission. These findings do not support the use of sodium nitrite... read more

Prediction of Neurological Outcomes in Patients Treated With ECPR

Prediction of Neurological Outcomes in Patients Treated With ECPR

This prognostic study develops and validates a prediction model for neurological outcomes of patients with out-of-hospital cardiac arrest with shockable rhythm treated with extracorporeal cardiopulmonary resuscitation. A... read more

Decrease in CPR Initiation During COVID-19 Outbreak

Decrease in CPR Initiation During COVID-19 Outbreak

During the COVID-19 period, we observed decreased initiation of CPR by bystanders and first aid providers for BLS, and decreased ALS by the MMT, regardless if subjects were infected with SARS-CoV-2 or not. ROSC rates... read more

Microtools to Identify and Resuscitate Microcirculatory Dysfunction in Critically Ill Patients

Microtools to Identify and Resuscitate Microcirculatory Dysfunction in Critically Ill Patients

Despite recent advances in the timely restoration of impairments in the oxygen supply chain to the tissue (Yealy et al. 2014; Peake et al. 2014; Mouncey et al. 2015), circulatory shock remains a major contributor to mortality... read more

The Use of Venous Doppler to Predict Adverse Kidney Events in a General ICU Cohort

The Use of Venous Doppler to Predict Adverse Kidney Events in a General ICU Cohort

This study indicates that portal and hepatic flows may be clinical useful tools to help identify patients at risk for renal injury. It is likely that they are indicative of elevated right atrial pressure causing venous congestion,... read more

Viscoelastic Hemostatic Assay Augmented Protocols for Major Trauma Hemorrhage

Our international randomized trial has evaluated the role of VHAs to individualize care and augment empiric hemostatic resuscitation in the challenging and time-critical environment of trauma care. Empiric haemostatic therapy... read more

TEG for Hypocoagulable Patients with Non-Traumatic Bleeding

TEG for Hypocoagulable Patients with Non-Traumatic Bleeding

Thromboelastogram (TEG) has been extensively studied in trauma and surgical patients, but has not been well studied in nontraumatic bleeding, nor has its use been well evaluated in the emergency department. This study... read more

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

Appropriate clinical decision-making in the initial evaluation and management of trauma patients in the emergency department is critical to optimize patient outcomes. This supplement provides evidence-based recommendations... read more

Scvo2 in Sepsis: A Measurement Provided by Respiratory Care Practitioners

Scvo2 in Sepsis: A Measurement Provided by Respiratory Care Practitioners

When treating patients with sepsis, intensive care unit (ICU) and emergency department clinicians have learned that improved outcomes occur when staff members work together as a team. This article outlines the value of central... read more

Critical Care and Hospitalist Medicine Made Ridiculously Simple

Critical Care and Hospitalist Medicine Made Ridiculously Simple

A fundamental and thorough guide to the treatment of hospitalized patients in critical care situations, "Critical Care and Hospitalist Medicine Made Ridiculously Simple" provides both introductory information as well as a... read more