Staphylococcus Epidermidis Infections Linked to ICU Septic Shocks

Bloodstream infections caused by Staphylococcus epidermidis (SE-BSI) may lead to septic shock in patients admitted to intensive care unit (ICU), according to a study. For the study, researchers looked at a retrospective... read more

Staphylococcus Epidermidis Infections Linked to ICU Septic Shocks

The Contribution of Procalcitonin, C-Reactive Protein and Interleukin-6 in the Diagnosis and Prognosis of Surgical Sepsis

The mortality rate was quite high in our study, consistent with the elevated serum biomarker concentrations, which were higher in non-survivors compared with survivors. C-reactive protein (CRP) and IL-6 were the most effective... read more

The Contribution of Procalcitonin, C-Reactive Protein and Interleukin-6 in the Diagnosis and Prognosis of Surgical Sepsis

Doppler Ultrasound Identified Venous Congestion in Septic Shock

Venous congestion is a pathophysiological state where high venous pressures cause organ edema and dysfunction. Venous congestion is associated with worse outcomes, particularly acute kidney injury (AKI), for critically ill... read more

Doppler Ultrasound Identified Venous Congestion in Septic Shock

Artesunate Treatment in Severely Injured Patients with Traumatic Hemorrhage

In this study of critically injured trauma patients with major hemorrhage, artesunate did not improve organ dysfunction and was potentially associated with an increased VTE risk. Future studies that focus on immune responses... read more

Artesunate Treatment in Severely Injured Patients with Traumatic Hemorrhage

Adjunctive Intravenous Then Oral Vitamin C for CAP Patients

Patients hospitalised with community acquired pneumonia (CAP) have low peripheral blood vitamin C concentrations and limited antioxidant capacity. The feasibility of a trial of vitamin C supplementation to improve patient... read more

Adjunctive Intravenous Then Oral Vitamin C for CAP Patients

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

The study revealed that the utilization of non-ICU sophisticated ventilators was linked to a higher mortality rate when compared to standard ICU ventilators in COVID-19 patients with ARDS. However, given the shortage and... read more

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

Effect of Antimicrobial De-escalation Strategy on 14-day Mortality Among ICU Patients

The prevalence of antimicrobial de-escalation (ADE) strategy was low among intensive care unit patients. The ADE strategy demonstrated a protective effect or no adverse effect on 14-day mortality compared to the No Change... read more

Effect of Antimicrobial De-escalation Strategy on 14-day Mortality Among ICU Patients

Elevation of D-dimer Levels Associated with Early Need for Mechanical Ventilation Support in COVID-19 Patients

Hypoxia and thrombosis are hallmarks of severe COVID-19, and each of them can exaggerate the other, adding to the magnitude of the disease. Our study proposes that D-dimer, commonly used as a marker of thrombosis, can also... read more

Elevation of D-dimer Levels Associated with Early Need for Mechanical Ventilation Support in COVID-19 Patients

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

Remdesivir, an antiviral medication, may benefit patients who are infected with mild or moderate forms of COVID-19 infection. Several research findings have suggested the safety and efficacy of remdesivir for a five- to 10-day... read more

Updated Systematic Review on Remdesivir’s Safety and Efficacy in COVID-19 Patients

Multimodal vs. Intraoperative Opioid Free Anesthesia for Laparoscopic Sleeve Gastrectomy

Anesthesia for laparoscopic sleeve gastrectomy and perioperative management remains a challenge. Several clinical studies indicate that opioid-free anesthesia (OFA) may be beneficial, but there is no consensus on the most... read more

Multimodal vs. Intraoperative Opioid Free Anesthesia for Laparoscopic Sleeve Gastrectomy

Minimally Invasive Intrathoracic Negative-pressure Therapy and FlexVATS for Patients with Pleural Empyema

To determine whether a new surgical method using a flexible endoscope (FlexVATS) to perform sparing debridement and apply negative-pressure therapy without extensive decortication may be an alternative treatment option for... read more

Minimally Invasive Intrathoracic Negative-pressure Therapy and FlexVATS for Patients with Pleural Empyema

Safety and efficacy of dexmedetomidine vs ketamine vs midazolam combined with propofol in gastrointestinal endoscopy for cancer patients

In cancer patients who underwent GI endoscopy, dexmedetomidine-propofol and ketamine-propofol had better sedation efficacy [lower achievement time of RSS 3–4, total propofol dose, and eye-opening time] compared to midazolam-propofol... read more

Safety and efficacy of dexmedetomidine vs ketamine vs midazolam combined with propofol in gastrointestinal endoscopy for cancer patients

Dexmedetomidine for EOL Sedation

This study demonstrates a reduction in breakthrough medication requirements, particularly benzodiazepines, for patients sedated with dexmedetomidine at end of life (EOL). The dexmedetomidine cohort required less breakthrough... read more

Dexmedetomidine for EOL Sedation

Severe Hypertriglyceridemia: A 10-Year Review

This study shows the morbidity profile associated with severe hypertriglyceridemia (SHTG), with a high level of ICU admissions and also a high level of the use of plasmapheresis. In our population, this approach had good... read more

Severe Hypertriglyceridemia: A 10-Year Review

Mild Hypercapnia or Normocapnia after OHCA

In patients with coma who were resuscitated after out-of-hospital cardiac arrest (OHCA), targeted mild hypercapnia did not lead to better neurologic outcomes at 6 months than targeted normocapnia. A total of 1,700 patients... read more

Mild Hypercapnia or Normocapnia after OHCA

Early Control of Elevated Blood Pressure – INTERACT3

Early control of elevated blood pressure is the most promising treatment for acute intracerebral hemorrhage. We aimed to establish whether implementing a goal-directed care bundle incorporating protocols for early intensive... read more

Early Control of Elevated Blood Pressure – INTERACT3

Pulmonary Artery Catheter Use and Mortality in the Cardiac ICU

The appropriate use of pulmonary artery catheters (PACs) in critically ill cardiac patients remains debated. There is wide variation in the use of PACs that is not fully explained by patient level-factors and appears driven... read more

Pulmonary Artery Catheter Use and Mortality in the Cardiac ICU

Checklists and Consistency of Care After Resuscitation From IHCA

In-hospital cardiac arrest (IHCA) with the return of spontaneous circulation (ROSC) is a clinical scenario associated with potentially devastating outcomes. Our study demonstrated improved consistency in completing post-ROSC... read more

Checklists and Consistency of Care After Resuscitation From IHCA