Whole Body Hyperthermia Appeared to Reduce Depression Symptoms

Whole-body hyperthermia holds promise as a safe, rapid-acting, antidepressant modality with a prolonged therapeutic benefit. Results from the current study suggest that WBH holds promise as a safe, rapid-acting, antidepressant... read more

Whole Body Hyperthermia Appeared to Reduce Depression Symptoms

Increased ICU Costs for Opioid Overdoses

ICU costs for treating opioid overdose patients increased 58% in a seven-year span, and annual deaths almost doubled, according to a study that included 162 academic hospitals. ICU admissions increased 34% over the study... read more

Increased ICU Costs for Opioid Overdoses

Extended ICU Visitation Model Reduces Delirium

In this medical-surgical ICU, an extended visitation model was associated with reduced occurrence of delirium and shorter length of delirium/coma and ICU stay. Two hundred eighty-six patients were enrolled (141 restricted... read more

Extended ICU Visitation Model Reduces Delirium

nutritionDay ICU

An worldwide prevalence study to determine the nutrition practice in the ICUs and the associated outcome across the world, a yearly 1 day cross sectional audit was performed from 2007 to 2013. This very large collaborative... read more

nutritionDay ICU

Potentially modifiable factors contributing to sepsis-associated encephalopathy

Acute renal failure and common metabolic disturbances represent potentially modifiable factors contributing to sepsis-associated encephalopathy. However, a true causal relationship has yet to be demonstrated. Our study confirms... read more

Potentially modifiable factors contributing to sepsis-associated encephalopathy

Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis

Secondary retrospective analysis of a single-center sepsis registry. Vasoactive-Inotropic Score in pediatric sepsis patients is independently associated with important clinically relevant outcomes including ICU length of... read more

Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis

Safety Hazards During Intrahospital Transport

A prospective observational study. Data from participant observations of the intrahospital transport process were collected over a period of 3 months. Findings suggest that intrahospital transport is a hazardous process for... read more

Safety Hazards During Intrahospital Transport

Most ICU Patients Underfed

A large international multicentre cohort study shows that most of the patients are underfed during their ICU stay. In their findings published in the journal Clinical Nutrition, researchers say most of the patients in intensive... read more

Most ICU Patients Underfed

SOFA Effective Pediatric Version

An age-adjusted version of the Sequential Organ Failure Assessment score for sepsis has been found to be at least as good, if not better than, other pediatric organ dysfunction scores at predicting in-hospital mortality.... read more

SOFA Effective Pediatric Version

Stress Ulcer Prophylaxis in the ICU (SUP-ICU)

Stress ulcer prophylaxis (SUP) is standard of care in the intensive care unit (ICU), however the quantity and quality of evidence is low and potential harm has been reported. The aim of the SUP-ICU trial is to asses the overall... read more

Stress Ulcer Prophylaxis in the ICU (SUP-ICU)

Double Mortality Risk for Depressed Heart Disease Patients

Among 24,000 patients with heart disease studied over many years, those who suffered from depression were at twice the risk of dying, according recently published findings from Intermountain Healthcare. A statistical analysis... read more

Double Mortality Risk for Depressed Heart Disease Patients

Can Electronic Alerts Help Identify Sepsis in Sick Children?

A two-step electronic alert system successfully reduced missed sepsis diagnoses in children by 76 percent. The new pediatric protocol, which incorporates the use of vital signs, risk factors, and a clinician's judgment,... read more

Can Electronic Alerts Help Identify Sepsis in Sick Children?

This Startup Could Revolutionize How We Fight Infectious Diseases

Karius Test has raised $50 million to develop a novel technology that can detect more than 1,000 infectious diseases, without requiring the usual trial-and-error tests. The test is expensive at $2,000, and is meant for use... read more

This Startup Could Revolutionize How We Fight Infectious Diseases

Muscle Oxygenation as Indicator of Shock Severity

The aim of this pilot study was to evaluate the potential of a new noninvasive optical measurement of muscle oxygenation (MOx) to identify shock severity in patients with suspected sepsis. We demonstrate that noninvasive... read more

Muscle Oxygenation as Indicator of Shock Severity

International Survey of Critically Ill Children with Acute Neurological Insults

Margaret Parker, MD, MCCM, speaks with Ericka L. Fink, MD, MS, about the PANGEA study (Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment), published in the April 2017 issue... read more

International Survey of Critically Ill Children with Acute Neurological Insults

Improving Long-Term Outcomes Research for ARF

Alison Turnbull, DVM, MPH, PhD discusses the heterogeneity in outcome measures in our field and the need for a Core Outcome Measurement Set (COMS) to standardize reporting of important outcomes. As part of the consensus process,... read more

Improving Long-Term Outcomes Research for ARF

Readmissions for Recurrent Sepsis: New or Relapsed Infection?

Sepsis hospitalizations are frequently followed by hospital readmissions, often for recurrent sepsis. However, it is unclear how often sepsis readmissions are for relapsed/recrudescent vs. new infections. The aim of this... read more

Readmissions for Recurrent Sepsis: New or Relapsed Infection?

Anabolic and Anticatabolic Agents in Critical Care

Profound metabolic derangements occur in critically ill patients; this hypermetabolic response is a major contributor to adverse outcomes. Despite the pharmacological therapies currently available to counteract this devastating... read more

Anabolic and Anticatabolic Agents in Critical Care