Tag: study
Angiotensin II in Post Cardiopulmonary Bypass Vasoplegia
Post cardiopulmonary bypass vasoplegia is common, and associated with poor outcomes. Traditional management strategies involving escalating doses of catecholamines, vasopressin and adjuncts such as methylene blue and hydroxycobalamin... read more
Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children
In this cohort study of 315 children with COVID-19 and 1402 children with seasonal influenza, there were no statistically significant differences in the rates of hospitalization, admission to the intensive care unit, and... read more
Quality of Life of Intensive Care Unit-Acquired Weakness Symptoms in Long-Term Intensive Care Survivors
Intensive care unit-acquired weakness (ICUAW) symptoms were disturbingly common in the majority of long-term survivors, indicating that symptoms persist up to 10y and frequently impair QoL. However, only a small number of... read more
Sepsis and the Obesity Paradox: Size Matters in More Than One Way
Our retrospective analysis suggests that although patient size (i.e., body mass index) is a predictor of in-hospital death among all-comers with sepsis—providing further evidence to the obesity paradox—it adds that illness... read more
Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs
Nasotracheal intubation is used in a minority of U.S. PICUs and mainly among young cardiac patients. Nasotracheal intubation is associated with a lower rate of unplanned extubations in this patient population. Future... read more
From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response
Between June 18 and Aug 3, 2020, Ministry of Health of the Russian Federation enrolled 76 participants to the two studies (38 in each study). In each study, 9 volunteers received rAd26-S in Phase 1, nine received rAd5-S in... read more
Hydroxychloroquine With or Without Azithromycin
Among patients hospitalized with mild-to-moderate COVID-19, the use of hydroxychloroquine, alone or with azithromycin, did not improve clinical status at 15 days as compared with standard care. A total of 667 patients... read more
Effects of Telemedicine ICU Intervention on Care Standardization and Patient Outcomes
In this pre-post observational study, telemedicine ICU intervention was associated with improvements in care standardization and decreases in ICU and hospital mortality and length of stay. The mortality benefits were mediated... read more
Asthma Among Hospitalized Patients with COVID-19 and Related Outcomes
Among hospitalized patients 65 years or younger with severe COVID-19, asthma diagnosis was not associated with worse outcomes, regardless of age, obesity, or other high-risk comorbidities. Future population-based studies... read more
Evaluation of SARS-CoV-2 Serology Assays Reveals a Range of Test Performance
Appropriate use and interpretation of serological tests for assessments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and potential immunity require accurate data on assay performance.... read more
Artificial Neural Networks Improve Prediction and Risk Classification in ICU Patients
A supervised machine learning model using artificial neural networks (ANN) predicted neurological recovery, including survival excellently, and outperformed a conventional model based on logistic regression. Among the data... read more
EPSS vs. Fractional Shortening for LV Function – Is EPSS Good Enough?
In a recent issue of the Journal of Ultrasound through AIUM, Weekes et al. (and Kendall et al in AM J EM) talk about a hot topic that emergency and critical care physicians hold dear to them – the EPSS , or E-point septal... read more
Variation in Hospital Visitor & ICU Communication Policies Due to COVID-19
A new study documents how 49 of those hospitals reacted, and how those efforts varied. It finds that virtually all hospitals put in place a "no visitors" blanket policy. But 59% of hospitals did allow some exceptions to this... read more
Perceived Barriers to Rapid Response Team Activation Among Nurses
The purpose of this literature review was to investigate the major barriers nurses face when it is necessary to seek additional assistance and resources by calling the rapid response team (RRT) in order to manage and stabilize... read more
Prone Positioning in Non-intubated Patients with COVID-19
As the COVID-19 pandemic has put severe stress and strain on the capacity of hospitals around the world, concerted efforts have been made to evaluate therapeutics aimed at preventing the need for mechanical ventilation. The... read more
Impact of Cardiovascular Risk Profile on COVID-19 Outcome
This study investigates the extent of cardiac comorbidities and complications among hospitalized patients with COVID-19. Cardiovascular complications are frequent among COVID-19 patients, and might contribute to adverse... read more
A Randomised Trial of High-flow Nasal Cannula in Infants with Moderate Bronchiolitis
In patients with moderate bronchiolitis, there was no evidence of lower rate of escalating respiratory support among those receiving HFNC therapy. The analyses included 268 patients among the 2621 infants assessed for... read more
Laboratory Features of Severe vs. Non-severe COVID-19 Patients in Asian Populations
This meta-analysis provides evidence for the differentiation of severe cases of COVID-19 based on laboratory test results at the time of ICU admission. Future well-methodologically designed studies from other populations... read more
Fit-testing of N95/P2-masks to Protect Healthcare Workers
In the context of COVID-19, well fitted respirators e.g. N95/P2-masks are recommended as part of personal protective equipment when performing aerosol generating procedures. Fit-checking is recommended prior to donning... read more
Acute on Chronic Liver Failure in the ICU
Liver Failure may constitute one of the least favorite disease processes for anyone routinely taking care of critically ill patients. Intensivist and hepatology circles have begun to describe a specific population known as... read more
Pulmonary Embolism in COVID-19 Patients in France
Pulmonary embolism (PE) in the context of coronavirus disease 2019 (COVID-19) appears to be driven largely by inflammation and coagulopathy rather than by traditional risk factors for thromboembolism. Study results suggest... read more
Non-Invasive Cardiac Imaging for LVAD and OHT During COVID-19
Considerations for cardiac imaging in the COVID-19 era include thoughtful patient and study selection with a goal to limit the overall number of tests. General recommendations are as follows: Defer routine or low-risk... read more
