Hemodynamic Stabilization Using CRRT and cIVNa Combination Therapy

Compared with conventional continuous renal replacement therapy (CRRT), combination therapy of CRRT and continuous intravenous sodium infusion therapy (cIVNa) increased blood pressure, enhanced urinary volume, and reduced... read more

Inadequate Empirical Antibiotic Therapy in VAP: Risk Factors and Outcomes

Ventilator-associated pneumonia (VAP) caused by MDR pathogens were highly likely to receive inadequate empirical antibiotic therapy. The mortality rate and intubation duration were significantly longer in inadequately treated... read more

Aminoglycosides Impact on Survival Rate and Renal Outcomes in Patients with Urosepsis

The addition of aminoglycosides to beta-lactam therapy in critically ill patients with urosepsis did not significantly improve 30-day survival. Furthermore, aminoglycosides were not associated with worse renal outcomes.... read more

Femoral Head Osteonecrosis in Post-COVID-19 Patients

This study provides an insight into the relationship between COVID-19-related factors and the development of osteonecrosis of the femoral head (ONFH), emphasizing the critical role of cumulative steroid dose as the primary... read more

Baricitinib Use in Children with Severe COVID-19 Infection

Baricitinib appears safe for both immunocompetent and immunocompromised children hospitalized for severe COVID-19. Most adverse events did not inhibit therapy administration, and there were no deaths following the initiation... read more

The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees

This new book will serve as a useful resource for all pharmacists involved in the management of critically ill patients, whatever their level of experience and training. There are few textbooks aimed specifically at critical... read more

The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees

Management of ARDS COVID-19 Patients Using Hemoperfusion and CRRT

Combined hemoperfusion (HP) and continuous renal replacement therapy (CRRT) hold promise as a potential intervention for severe COVID-19 cases with multiple organ dysfunction, leading to improved clinical outcomes. Fifty-six... read more

Sepsis: Staging and Potential Future Therapies

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Variability in pathogenesis and complex pathophysiology often delay diagnosis and create significant challenges for clinical... read more

Sepsis: Staging and Potential Future Therapies

Acid-Base, Fluids, and Electrolytes Made Ridiculously Simple

A brief, highly readable book providing the clinician with a straightforward approach to solving even the most complex, acid-base, fluid, and electrolyte problems. Useful to medical students, interns and residents, nurses... read more

Acid-Base, Fluids, and Electrolytes Made Ridiculously Simple

Association Between Osteopontin and Apolipoprotein E gene Polymorphisms and Vancomycin-induced AKI

Individuals carrying specific genotypes of APOE (e2e3) were more prone to develop vancomycin-induced acute kidney injury (AKI), per se. This could apply to other nephrotoxic agents as well. We also observed a significant... read more

CAFe Model a Significant Step Forward in Coronary Artery Disease Progression Simulation

The multi-physics simulation (CAFe) model represents a significant step forward in the simulation of coronary artery disease (CAD) progression and offers a promising tool for advancing our understanding of the disease. This... read more

Opioid Use in Critical Care: A Practical Guide

This book provides a concise yet comprehensive overview on the use of opioids in the ICU, offering practical, real-world recommendations on opioid utilization and alternative therapies. The text explains the physiology... read more

Opioid Use in Critical Care: A Practical Guide

Pharmacokinetics of Opioid Infusions in the Adult ICU Setting

To counter these pharmacokinetics (PKs) alterations, new therapeutic avenues must be further explored in the ICU to individualize opioid infusions. Embase, MEDLINE, PubMed, CINAHL, and Evidence-Based Medicine Reviews (EBMR)... read more

Clinical Efficacy of Nafamostat Mesylate-assisted CRRT Therapy in SA-AKI Patients

Nafamostat Mesylate (NM)-assisted continuous renal replacement therapy (CRRT) therapy significantly improves the therapeutic efficacy of patients with sepsis-associated acute kidney injury (SA-AKI). This combined approach... read more

Pre-ICU Statin Use, AKI and in Hospital Mortality in Sepsis Patients

Pre-ICU statin therapy is associated with a lower risk of acute kidney injury (AKI), and improved in-hospital survival among obese patients with sepsis, suggesting its potential role as a protective measure in this high-risk... read more

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

This is the first book exploring the unique dynamics created by a multidisciplinary trauma team and how crisis management strategies can improve teamwork and communication and, potentially, improve patient resuscitation... read more

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

Handbook of ICU Therapy

This popular handbook provides a practical guide to managing common and important problems in the critically ill patient, as well as sufficient background information to enable understanding of the principles and rationale... read more

Handbook of ICU Therapy

Therapeutic Hypothermia After Cardiac Arrest

Therapeutic hypothermia has emerged as a very important treatment option for patients with cardiac arrest as it provides significant protection from developing neurologic injury once the patient has been successfully resuscitated.... read more

Therapeutic Hypothermia After Cardiac Arrest

CAR-T Therapy – Critical Care Considerations of Chimeric Antigen Receptor

Despite significantly improving the treatment of blood cancers, CAR T-cell therapy still faces significant hurdles due to its complex and varied toxicities, which require ongoing research to optimize management; while understanding... read more

Handbook of Intravenous Fluids

This easy to use pocket book covers all aspects of intravenous fluid therapy in critically ill patients from applied physiology to bedside clinical management succinctly. It includes updated and evidence-based content on... read more

Handbook of Intravenous Fluids

Cellular Therapy with Mesenchymal Stromal Cells in Sepsis

Cellular therapy with mesenchymal stromal cells (MSCs) is a promising therapeutic modality in sepsis. Positive effects are mainly associated with frequent infusions and the dose of 1 × 106 cell/kg. Larger scale studies... read more

Handbook of Sepsis

This recently released practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the ICU. Readers will find information on... read more

Handbook of Sepsis