Tag: treatment
Minimally Invasive Intrathoracic Negative-pressure Therapy and FlexVATS for Patients with Pleural Empyema
To determine whether a new surgical method using a flexible endoscope (FlexVATS) to perform sparing debridement and apply negative-pressure therapy without extensive decortication may be an alternative treatment option for... read more
Propofol in ICU Settings: Understanding and Managing Anti-Arrhythmic, Pro-Arrhythmic Effects, and Propofol Infusion Syndrome
Propofol has revolutionized anesthesia and intensive care medicine owing to its favorable pharmacokinetic characteristics, fast onset, and short duration of action. This drug has been shown to be remarkably effective in numerous... read more
Early Control of Elevated Blood Pressure – INTERACT3
Early control of elevated blood pressure is the most promising treatment for acute intracerebral hemorrhage. We aimed to establish whether implementing a goal-directed care bundle incorporating protocols for early intensive... read more
Heparin-Binding Protein Predictive Value and D-Dimer in Sepsis Patients
As common clinical indicators for predicting sepsis, both HBP and D-dimer have high diagnostic effectiveness. Furthermore, the combined application of these two biomarkers can achieve favorable effects. In clinical practice,... read more
Effective Treatment for Combined Amlodipine and Metformin Overdose
The combined toxicity of amlodipine and metformin is a rarely reported phenomenon in the literature. The management varies depending on the clinical status of the patient. We present a case that was managed successfully... read more
Rapid Sepsis Tests Using Magnetic Nanoparticles
Qun Ren, an Empa researcher, and her team are currently developing a diagnostic procedure that can rapidly detect life-threatening blood poisoning caused by staphylococcus bacteria. Staphylococcal sepsis is fatal in up... read more
Oxford Textbook of Critical Care
The thoroughly revised 2nd edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely the book takes a problem-orientated approach... read more
Rescue TEE Might Diagnose Cardiac Arrest Faster
A Penn Medicine team is testing whether a new technology that gives live ultrasound images from inside a patient during CPR can help doctors get those answers faster. The device, called Rescue TEE, uses a tiny camera at the... read more
Thrombotic and Bleeding Complications During Antithrombotic Treatment
Remarkable progress has been made in the pharmacological management of patients with cardiovascular disease, including the frequent use of antithrombotic agents. Nonetheless, bleeding complications remain frequent and potentially... read more
Acute Traumatic Coma Awakening by Right Median Nerve Electrical Stimulation
Severe traumatic brain injury (TBI) leads to acute coma and may result in prolonged disorder of consciousness (pDOC). We aimed to determine whether right median nerve electrical stimulation is a safe and effective treatment... read more
Acute Respiratory Distress Syndrome
This book covers all clinical aspects of acute respiratory distress syndrome (ARDS), from definition to treatment, focusing on the more recent recommendations and evidence-based medicine. The addressed topics are the... read more
Acute Ischemic Stroke: Recent Advances in Reperfusion Treatment
Stroke is a major clinical challenge. The authors note that during the last 5–7 years, tremendous progress was achieved in the reperfusion treatment of acute ischemic stroke during its first few hours from symptom onset.... read more
Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19
Randomized clinical trials (RCTs) of therapeutic-dose heparin in patients hospitalized with COVID-19 produced conflicting results, possibly due to heterogeneity of treatment effect (HTE) across individuals. Better understanding... read more
Combination Treatment of Persistent COVID-19 in Immunocompromised Patients
Little data exists to guide the treatment of persistent COVID-19 in immunocompromised patients. We have employed a unique protocol combining tixegavimab/cilgavimab, and short-term combination antivirals including remdesivir.... read more
Differential Diagnosis and Cause-specific Treatment During OHCA
The cardiopulmonary resuscitation (CPR) guidelines recommend identifying and correcting the underlying reversible causes of out-of-hospital cardiac arrest (OHCA). However, it is uncertain how often these causes can be... read more
Biggest AMR dilemma: to give, or not to give antibiotics?
Sepsis (a dysregulated reaction of the body to infection with 50 million cases per year) must be treated with antibiotics as soon as it is suspected — ideally, within the first hour. Antibiotics are thus easily administered... read more
Mechanical Ventilation from Pathophysiology to Clinical Evidence
This new book aims to give a comprehensive overview of the current challenges and solution posed to the health care professionals who need to use mechanical ventilation to treat their patients. Mechanical ventilation is... read more
Troponins for SVT Set the Stage for Patient Harm
Many laboratory tests are routinely ordered for reassurance. We almost always order a hemoglobin and pregnancy test when a patient has syncope, despite knowing the vast majority will be normal. These tests are accurate... read more
