Real-time AI prediction for major adverse cardiac events in emergency department patients with chest pain
An artificial intelligence (AI) real-time prediction model is a promising method for assisting physicians in predicting major adverse cardiac events (MACE) in ED patients with chest pain. Further studies to evaluate the impact... read more
Shedding Light on a Hidden Source of Septic Shock with POCUS
Septic shock has a high mortality rate, estimated to be higher than 40% [1], increasing as time passes without appropriate treatment. Hence, correct diagnosis of the cause of sepsis is essential to provide correct antibiotic... read more
Angiotensin II in Post Cardiopulmonary Bypass Vasoplegia
Post cardiopulmonary bypass vasoplegia is common, and associated with poor outcomes. Traditional management strategies involving escalating doses of catecholamines, vasopressin and adjuncts such as methylene blue and hydroxycobalamin... read more
Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children
In this cohort study of 315 children with COVID-19 and 1402 children with seasonal influenza, there were no statistically significant differences in the rates of hospitalization, admission to the intensive care unit, and... read more
ECG’s for the Emergency Physician 1
With over 200 traces to test your knowledge, this book is a first class learning tool for emergency physicians. Basic student-level knowledge of ECGs is assumed, so the reader can move directly to learning about the more... read more
Quality of Life of Intensive Care Unit-Acquired Weakness Symptoms in Long-Term Intensive Care Survivors
Intensive care unit-acquired weakness (ICUAW) symptoms were disturbingly common in the majority of long-term survivors, indicating that symptoms persist up to 10y and frequently impair QoL. However, only a small number of... read more
Sepsis and the Obesity Paradox: Size Matters in More Than One Way
Our retrospective analysis suggests that although patient size (i.e., body mass index) is a predictor of in-hospital death among all-comers with sepsis—providing further evidence to the obesity paradox—it adds that illness... read more
Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs
Nasotracheal intubation is used in a minority of U.S. PICUs and mainly among young cardiac patients. Nasotracheal intubation is associated with a lower rate of unplanned extubations in this patient population. Future... read more
LV Overloading Identified by Critical Care Echocardiography is Key in Weaning‑induced Pulmonary Edema
Spontaneous breathing trial (SBT) failure due to WIPO appears related to overloaded LV, including the worsening or development of mitral regurgitation, associated with excessive accumulated fluid balance. SBT-induced central... read more
Factors Behind Decline of VV ECMO to Support Neonatal Respiratory Failure
The majority of U.K. centers are unable to provide venovenous extracorporeal membrane oxygenation (VV ECMO) for neonates due to concerns with availability and suitability of dual lumen cannulae. An alternative to be considered... read more
Pragmatic Approach to Inpatient Diabetes Management During COVID-19
The pandemic of COVID-19 has presented new challenges to hospital personnel providing care for infected patients with diabetes who represent more than 20% of critically ill patients in ICUs. Appropriate glycemic management... read more
From Russia with Love – “Sputnik V” COVID-19 Vaccine Generated an Immune Response
Between June 18 and Aug 3, 2020, Ministry of Health of the Russian Federation enrolled 76 participants to the two studies (38 in each study). In each study, 9 volunteers received rAd26-S in Phase 1, nine received rAd5-S in... read more
Sepsis and COVID-19: Perspectives From a Sepsis Coordinator
Coronavirus disease 2019 (COVID-19) has brought difficulties and disruptions to all corners of the world. As a sepsis coordinator, I can attest that the scientific and healthcare community in the United States has been particularly... read more
COVID-19: A Critical Analysis of Chloroquine and Hydroxychloroquine Clinical Pharmacology
Chloroquine and hydroxychloroquine have been used for over 60 years in the treatment of malaria, amoebic liver abscess, and several rheumatological conditions, but their clinical pharmacology is not well understood. COVID-19... read more
Hydroxychloroquine With or Without Azithromycin
Among patients hospitalized with mild-to-moderate COVID-19, the use of hydroxychloroquine, alone or with azithromycin, did not improve clinical status at 15 days as compared with standard care. A total of 667 patients... read more
Effects of Telemedicine ICU Intervention on Care Standardization and Patient Outcomes
In this pre-post observational study, telemedicine ICU intervention was associated with improvements in care standardization and decreases in ICU and hospital mortality and length of stay. The mortality benefits were mediated... read more
Bedside ECHO To Diagnose Native Valve Infective Endocarditis
Infective endocarditis (IE) is an important pathology to detect in the Emergency Department (ED), but the diagnosis is too often delayed or missed. IE ticks many boxes as a diagnosis we can "own" in Emergency Medicine (EM): 1.... read more
Training Multidisciplinary Healthcare Workers to Reinforce ICUs in Times of Need
ESICM is to carry out a C19 SPACE programme funded by the European Commission for the training of multidisciplinary healthcare professionals not regularly working in ICUs, to give extra support to ICUs during the COVID-19... read more
Effect of Hydrocortisone on Mortality and Organ Support in Patients with Severe COVID-19
Among patients with severe COVID-19, treatment with a 7-day fixed-dose course of hydrocortisone or shock-dependent dosing of hydrocortisone, compared with no hydrocortisone, resulted in 93% and 80% probabilities of superiority... read more
CDC Tells States How to Prepare for Covid-19 Vaccine by Early November
The Centers for Disease Control and Prevention has notified public health officials in all 50 states and five large cities to prepare to distribute a coronavirus vaccine to health care workers and other high-risk groups as... read more
Survey Finds More Than Half of Pediatric Cardiology Nurses Are Burned Out
More than half of nurses caring for children with cardiovascular conditions are emotionally exhausted and good working environments were linked with less burnout, according to a survey presented during ESC Congress 2020. Of... read more
Steroids Confirmed to Help Severely Ill COVID-19 Patients
In patients hospitalized with COVID-19, the use of dexamethasone resulted in lower 28-day mortality among those who were receiving either invasive mechanical ventilation or oxygen alone at randomization but not among those... read more
