Endotracheal Intubation Preoxygenation in Resource-limited Settings
Optimal preoxygenation strategies for endotracheal intubation (ETI) in LRS require both protocol adaptation and clinical resourcefulness. An individualized approach using the most feasible combination of techniques should... read more
Enhancing Early Mortality Prediction for Sepsis-associated ARDS Patients Using Machine Learning
This study utilized the MIMIC-IV, eICU CRD, and NWICU databases to construct and validate a machine learning model, SAFE-Mo, which predicts early mortality in patients with sepsis-associated acute respiratory distress syndrome... read more
Neurally Adjusted Ventilatory Assist Decreases the Requirement of Corticosteroids
This study aimed to evaluate the incidence of bronchopulmonary dysplasia (BPD) and the dosage of corticosteroids in extremely preterm infants with the implementation of neurally adjusted ventilatory assist (NAVA). This... read more
The Influencing Factors of Neonatal Extubation Failure
This study conducted a systematic review and meta-analysis of 22 studies, revealing significant differences in risk factors between the extubation success and failure groups. Subgroup analysis further showed variations in... read more
Increased Driving Pressure During Assisted Ventilation for Hypoxemic Respiratory Failure Is Associated with Lower ICU Survival
Driving pressure is marker of severity and a possible target for lung protection during controlled ventilation, but its value during assisted ventilation is unknown. Inspiratory holds provide an estimate of driving pressure... read more
Restrictive vs. Liberal Transfusion Strategy in Patients with Spontaneous ICH
Red blood cell transfusions are commonly administered to anemic patients with spontaneous intracerebral hemorrhage (ICH); however, the optimal hemoglobin threshold to initiate transfusion is uncertain in this population.... read more
Impact of Low-Dose Ketamine Infusion on Intracranial Pressure and Hemodynamics in Septic Shock Patients
Adult patients with septic shock, on hemodynamic support, had high-to-normal intracranial pressure (ICP). Low-dose continuous ketamine infusion as an adjunct sedative appeared to have favorable outcomes concerning ICP and... read more
Airway Management Success in Out-of-hospital Cardiac Arrest Using Different Devices
Although this study found no significant difference in the FPS rates between direct laryngoscopy and video laryngoscopy, the more frequent use of conventional laryngoscopy was associated with a lower FPS rate among anesthetists.... read more
The Role of Neuroimaging in Brain Death Diagnosis
Brain death remains a medically and ethically complex topic, due to its religious and philosophical implications, despite the attempt to "scientificise" what is death and what is not. BD is characterized by a lack of universal... read more
Altered Lower Brainstem Neurophysiological Response Is Associated with Mortality In Deeply Sedated Critically Ill Patients
Absent cough reflex is associated with mortality in intensive care unit (ICU) patients requiring deep sedation, suggesting that lower brainstem dysfunction contributes to adverse outcomes. We conducted a multicenter observational... read more
Anticoagulation Management and Outcomes in Critically Ill Patients with Acute Mesenteric Ischemia
This study suggests a significant survival benefit of early full-dose anticoagulation in ICU patients with acute mesenteric ischemia and no difference in hemorrhagic complications. Early full-dose anticoagulation and revascularization... read more
TBI Management in the ICU
Despite advances in the management of traumatic brain injury (TBI) in the intensive care unit (ICU), and the implementation of new diagnostic techniques and monitoring modalities, the rate of poor neurological outcomes remains... read more
TBI: Quantifying Methodological Uncertainties and Navigating Feasibilities in Monitoring of Cerebral Autoregulation
Traumatic brain injury (TBI) remains a critical medical challenge due to its heterogeneous nature and complex pathophysiological mechanisms. Individualized management of TBI patients, taking advantage of such technologies... read more
Prevalence and Outcomes of Shock in Internal Medicine Patients
This retrospective observational study investigated the incidence, management, and outcomes of 125 shock patients admitted to the internal medicine department of a referral university hospital in Bangkok, Thailand, addressing... read more
Severe Listeriosis in the ICU: Critical Insights from a Multicenter Study
A retrospective multicenter study across 23 French hospitals over 10 years analyzed critically ill ICU patients with culture-confirmed "Listeria monocytogenes" infections. The study aimed to describe patient characteristics,... read more
Seraph-100 Hemoperfusion: Clearing Pathogens and Enhancing Outcomes in Sepsis
This study evaluated Seraph-100 hemoperfusion (HP) as a treatment for sepsis in intensive care unit (ICU) patients admitted after cardiac surgery for infective endocarditis (IE). Thirteen septic patients received Seraph-100... read more
Push-Dose Epinephrine Use in the Emergency Department
A retrospective multi-site cohort study investigated the use of push-dose epinephrine (PDE) in emergency departments (EDs) for managing hypotension in critically ill patients. Recognizing the limited ED-specific data compared... read more
Sepsis and Septic Shock: An Issue of Critical Care Clinics
Shock is caused by the decreased flow of blood to the body tissues due to circulatory system related problems. Sepsis refers to a life-threatening condition where the body causes injury to its own organs and tissues in response... read more
Impact of Esketamine vs. Remifentanil on Hemodynamics and Outcomes in Mechanically Ventilated Septic Shock
This single-center, prospective, randomized, controlled pilot study compared the hemodynamic effects and prognosis of esketamine versus remifentanil, both used in combination with propofol, for sedation and analgesia in patients... read more
Evaluating Remimazolam for ED Procedural Sedation Effectiveness and Patient Satisfaction
This study evaluated the safety and efficacy of remimazolam, an ultra-short acting benzodiazepine, for procedural sedation in the emergency department (ED). The primary aim was to compare its administration by emergency medicine... read more
Comparing Outcomes of COVID-19 and Influenza in Hospitalized European Adults
A study conducted through the EuroSAVE Network from December 2021 to March 2024 in five European middle-income countries/areas compared the odds of severe outcomes and death among hospitalized patients meeting the WHO severe... read more
Hemodynamics in the Echocardiography Laboratory
The book provides a practically focused review of the latest techniques used for hemodynamic assessment in the echocardiography laboratory. It features a methodical case-based approach covering how to measure hemodynamic... read more
