Hemolysis in Septic Patients with Acute Respiratory Failure: Prognostic Implications

This study highlights the critical role of hemolysis in sepsis and acute respiratory failure, showing a strong association with organ dysfunction. Hemolysis is notably frequent, especially in patients with septic shock... read more

Teaching Pearls in Noninvasive Mechanical Ventilation

This book uses real-world clinical case analyses of hot topics to provide insights into noninvasive mechanical ventilation (NIV). Written by leading international teachers and experts, it features a selection of "major... read more

Teaching Pearls in Noninvasive Mechanical Ventilation

Vitamin D Dynamics in Severe ARDS Patients on ECMO

This retrospective study investigated time-dependent changes in vitamin D levels and their correlation with disease severity and inflammation in 24 invasively mechanically ventilated patients with acute respiratory distress... read more

Troponin HsTnI: Predicting Outcomes in Covid-19 Patients

This observational retrospective cohort study of 325 patients diagnosed with COVID-19 aimed to determine the relationship between troponin levels and disease severity or mortality. Conducted at Mohammed VI CHU in Oujda... read more

Finding the Ultimate Sedative

Critically ill patients requiring invasive mechanical ventilation often need continuous sedation for pain and anxiety. Propofol, a GABA potentiator, and Dexmedetomidine, an α2-adrenergic receptor agonist, are commonly used... read more

Early Multimodal Rehabilitation Safely Accelerates Recovery for Ventilated Patients

This single-center, controlled clinical trial investigates the efficacy and safety of an early multimodal rehabilitation program (MRP) versus a late MRP in mechanically ventilated adult patients in the intensive care unit... read more

Propofol vs. Midazolam Infusion: Effects on Cardiovascular Stability in Critically Ill Patients

A study compared the effects of propofol and midazolam infusions on cardiovascular stability in 75 critically ill patients requiring sedation in the intensive care unit at Azadi and Tikrit Teaching Hospitals from December... read more

Amazon NFL Store

You can buy now official NFL merch for your favorite teams on Amazon.com Get ready for the NFL season! It's time to stock up on new gear, and the best place to find officially licensed jerseys and other merch is the Amazon... read more

Rib-Indexed POCUS vs. Chest X-Ray for Lung Recruitment Assessment in Ventilated Neonates with Moderate-Severe ARDS on Pulmonary Surfactant Therapy

Rib-indexed posterior approach POCUS is a reliable, radiation-free modality for real-time lung recruitment assessment in neonates with NARDS, demonstrating noninferiority to CXR. Notably, our study is the first to propose... read more

Causes of Death in Patients Undergoing ECPR

Refractory shock was the leading cause of death among our cohort of extracorporeal cardiopulmonary resuscitation (ECPR) patients, followed closely by neurological complications, while other causes are rare. In this post-hoc... read more

Mechanical Power Impact Normalized to Predicted Body Weight on Outcomes in Pediatric ARDS

Higher mechanical power (MP) was associated with fewer ventilator (VFD) and ICU free days (IFD). The causal effect of MP on VFD and IFD was fully mediated by the impairment in oxygenation. This is a post-hoc analysis of... read more

Anticoagulation Reversal Strategies for Warfarin Associated Acute Gastrointestinal Bleeding

Patients who received prothrombin complex concentrate (PCC) had a threefold increase in mortality compared to fresh frozen plasma (FFP), vitamin K alone, or no reversal, even after adjusting for severity of the bleeding.... read more

Endotracheal Tube Cuff Pressure Monitoring and VAP Occurrence

This study demonstrated that maintaining endotracheal tube cuff pressure at 30 cm H2O through monitoring every 8 h did not result in a greater incidence of under-inflation (pressures ... read more

Association Between Initial Blood Product Transfusion with a Higher Plasma-to-red Blood Cell Ratio and Mortality in Adults with Severe Bleeding Following Trauma

This study demonstrates that a high fresh-frozen plasma (FFP) to packed red blood cells (PRBC) ratio (>1:1.5) is associated with reduced 24-hour and 30-day mortality rates among trauma patients with massive hemorrhage. However,... read more

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Intubating critically ill patients is a process that requires a well-thought-out, step-by-step plan, specific to each patient. This book teaches the steps necessary to predict, prepare, perform, and provide pre and post-intubation... read more

Intubating the Critically Ill Patient: A Step-by-Step Guide for Success in the ED and ICU

Hemodynamic Stabilization Using CRRT and cIVNa Combination Therapy

Compared with conventional continuous renal replacement therapy (CRRT), combination therapy of CRRT and continuous intravenous sodium infusion therapy (cIVNa) increased blood pressure, enhanced urinary volume, and reduced... read more

A Novel Mechanism for COVID-19 Related Thrombotic Events: Platelet NO/ROS Equilibrium

The finding that platelet NO/ROS production imbalance contributes to the elevated risk of thrombotic events in COVID-19 has important clinical implications. Restoration of platelet NO production, as well as attenuation... read more

Inadequate Empirical Antibiotic Therapy in VAP: Risk Factors and Outcomes

Ventilator-associated pneumonia (VAP) caused by MDR pathogens were highly likely to receive inadequate empirical antibiotic therapy. The mortality rate and intubation duration were significantly longer in inadequately treated... read more

Red Book: Report of the Committee on Infectious Diseases

Extending an 8-decade tradition of excellence, Red Book® provides the most reliable and clinically useful information on the manifestations, etiology, epidemiology, diagnosis and treatment of more than 200 childhood infectious... read more

Red Book: Report of the Committee on Infectious Diseases

Early Acetaminophen Administration Associated with Lower Mortality Among ARDS Patients After Coronary Artery Bypass Grafting

The use of acetaminophen (APAP) at 48h after coronary artery bypass grafting (CABG)-acute respiratory distress syndrome (CABG-ARDS) was associated with lower early postoperative mortality, while shortening the length of hospital... read more

Thirst Management in Orotracheally Intubated and Mechanically Ventilated Patients

Symptom Management Theory (SMT)-based thirst management is an effective strategy. The 5 mL cold water spray method significantly reduces thirst intensity and distress in mechanically ventilated patients under fasting and... read more

COVID-19 Handbook: Navigating the Future of Healthcare

The COVID-19 Handbook: Navigating the Future of Healthcare provides factual, evidence-based information on the coronavirus disease 2019 (COVID-19) pandemic. Presented in a concise PDF format, this valuable COVID-19 resource... read more

COVID-19 Handbook: Navigating the Future of Healthcare