How I Manage Drainage Insufficiency on ECMO
As the use of extracorporeal membrane oxygenation (ECMO) expands, a systematic approach to the management of complex technical issues, such as drainage insufficiency, is essential to improving patient outcomes. Due to... read more
First Case of COVID-19 Complicated With Fulminant Myocarditis
COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure. This is the first report of COVID-19 complicated with fulminant myocarditis. The mechanism of cardiac pathology caused by COVID-19... read more
Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues
Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for... read more
Keeping the Coronavirus from Infecting Health-Care Workers
The message is getting out: #StayHome. In this early phase of the coronavirus pandemic, with undetected cases accelerating transmission even as testing ramps up, that is critical. But there are many people whom the country... read more
COVID-19 Pneumonia: ARDS or Not?
Even though it can meet the ARDS Berlin definition, the COVID-19 pneumonia is a specific disease with peculiar phenotypes. Its main characteristic is the dissociation between the severity of the hypoxemia and the maintenance... read more
A Novel ECG-biomarker for Cardiac Arrest During Hypothermia
Treatment of arrhythmias evoked by accidental or therapeutic hypothermia and rewarming remains challenging. We aim to find an ECG-biomarker that can predict ventricular arrhythmias at temperatures occurring in therapeutic... read more
Understanding Happy Hypoxemia Physiology During COVID-19
Happy hypoxemia is severe hypoxemia (poorly responsive to supplemental oxygen) without dyspnea. This isn't anything especially new – we have occasionally seen this since time immemorial. However, COVID is causing us to... read more
Comparison of Echocardiographic and Invasive Measures of Volaemia and Cardiac Performance in Critically Ill Patients
Static echocardiographic variables did not reliably reflect the volume state as defined by estimates of mean systemic filling pressure. There was no statistical or clinically robust relationship between static echocardiographic... read more
The Misunderstood Coagulopathy of Liver Disease
In patients with abnormal coagulation testing results in the setting of liver disease, INR and PT may be best used to provide the practitioner with information about the synthetic function of the liver but not to assess hemorrhagic... read more
COVID-19 Has Them Scared to Go Home
There are no statistics on how many health care workers and first responders have passed the virus to their children, spouses, or parents. But, thousands of American health care professionals have fallen ill so far – over... read more
Oxygen Escalation Therapy and Noninvasive Ventilation During COVID-19
We are in the midst of the COVID-19 pandemic. Many parts of the world have been ravaged by this virus, but disease severity varies significantly. There are several types of patients with COVID-19: those who have mild disease... read more
Characteristics of Health Care Personnel with COVID-19 in United States
As of April 9, 2020, the coronavirus disease 2019 (COVID-19) pandemic had resulted in 1,521,252 cases and 92,798 deaths worldwide, including 459,165 cases and 16,570 deaths in the United States. Health care personnel... read more
Addressing Anxiety Among Health Care Professionals During COVID-19
The coronavirus disease (COVID-19) pandemic has become one of the central health crises of a generation. The pandemic has affected people of all nations, continents, races, and socioeconomic groups. The responses required,... read more
Pediatric Airway Management in COVID-19 Patients
The severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic has challenged medical systems and clinicians globally to unforeseen levels. COVID-19's rapid spread has forced clinicians to care for patients with... read more
The Walls Manual of Emergency Airway Management
The Walls Manual of Emergency Airway Management is the world's most trusted reference on emergency airway management, and is the foundation text in the nationally recognized The Difficult Airway Course: Emergency and The... read more
Pharmacokinetics and Sedative Effects of Intranasal Dexmedetomidine in Ambulatory Pediatric Patients
These results demonstrate that intranasally (IN) dexmedetomidine is relatively rapidly absorbed and causes significant sedation in pediatric patients. Pharmacokinetics of IN dexmedetomidine in pediatric patients show quite... read more
Allocating Ventilators in a Pandemic
The COVID-19 pandemic has led to shortages of essential goods and services - from hand sanitizers to masks to beds to ventilators. Today, the healthcare system is facing the prospect of rationing medical goods and services. Mechanical... read more
Critical Care / ICU, Fluids, Electrolytes and Nutrition
Filled with detailed work-ups, treatments, pearls, illustrations, differential diagnosis and references. Everything you ever needed to know about critical care and nutrition issues in an easy to read and navigate format created... read more
Small Compact Resuscitation Device Safely Used on Patient with COVID-19
A small compact and portable resuscitation ventilation device built by PRIMEDIC OXYLATOR, was safely used to treat a patient with COVID-19 pneumonia in the intensive care unit (ICU). The Oxylator from Primedic is a combination... read more
Is COVID-19 ARDS?
Acute respiratory distress syndrome (ARDS) is a heterogeneous disease. It presents with a wide range of severity, varying degrees of hypoxemia and varying degrees of pulmonary mechanical impairment. Failure of hypoxemic vasoconstriction... read more
Optimizing Ventilator Use during the COVID-19 Pandemic
The COVID-19 outbreak is presenting unprecedented challenges to our health care system. According to our best projections, combined with information on the ground, the availability of precious medical resources will be limited... read more
Restoring Humanity In The ICU During COVID-19
Machines, tubes, wires, drugs, isolation, confusion... how can we protect the dignity and sanity of our patients when they're at their most vulnerable? Dr. Wes Ely is a Vanderbilt professor and critical care doc who can... read more
