Low Hand Hygiene Compliance in ICUs
Healthcare workers in intensive care units (ICUs) are regularly missing opportunities to clean their hands during the care of patients, despite its critical importance for infection control, according to new research being... read more
Going Into Hospital Far Riskier Than Flying
Millions of people die each year from medical errors and infections linked to health care and going into hospital is far riskier than flying according to World Health Organization. If you were admitted to hospital tomorrow... read more
Catheter Type in Pulmonary Embolism Intervention
Catheter based interventions for pulmonary embolism is on the rise. The rise in mainly in patients who present with submassive PE. The intent of intervention is to reduce clot burden. This is done to improve acute symptoms... read more
What is the lowest change in cardiac output that transthoracic echocardiography can detect?
In critically ill patients, changes in the velocity-time integral (VTI) of the left ventricular outflow tract, measured by transthoracic echocardiography (TTE), are often used to non-invasively assess the response to fluid... read more
Flu Killed Up to 54,800 People This Season
The flu has caused as many as 40.1 million illnesses and 54,800 deaths this season, according to CDC estimates based on the agency's most recent FluView report. During the 2017-18 flu season, an estimated 80,000 people died.... read more
Hyperinvasive approach to out-of hospital cardiac arrest using mechanical chest compression device
Authors introduce and offer a protocol of a proposed randomized study enrolling patients with witnessed OHCA presumably of cardiac origin planned to be initiated in Prague in 2012. Study will compare hyperinvasive approach... read more
Procalcitonin does not curb antibiotic use for lower respiratory tract infection
In the Procalcitonin Antibiotic Consensus Trial (ProACT), the use of a procalcitonin-guided antibiotic prescription guideline did not result in less exposure to antibiotics than did usual care among patients presenting to... read more
Internal Medicine Board Review E-Book: Certification and Recertification
Don't gamble on the most important exam of your career... ace the boards with The Johns Hopkins Internal Medicine Board Review! Brought to you from the birthplace of Internal Medicine and regarded as the most effective review... read more
To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU
A restrictive transfusion threshold is recommended in nearly all critically ill patients. This is at least noninferior to more liberal transfusion practice; in addition, a restrictive threshold has shown improved outcomes... read more
Feasibility, Safety, and Utility of Advanced Critical Care Transesophageal Echocardiography Performed by Pulmonary/Critical Care Fellows in a Medical ICU
Critical care transesophageal echocardiography is feasible, safe, and has clinical utility. It can be safely and effectively performed by fellows within the context of their critical care training with faculty supervision.... read more
Mobile Devices Are Reservoirs for the Transmission of Nosocomial Pathogens
Global burden of hospital-associated infection (HAI) is on the rise and contributes significantly to morbidity and mortality of the patients. Hundred percent contamination was found in mobile phones and hands of HCWs indicating... read more
Neutrophil Extracellular Traps Are Elevated in Patients with Pneumonia-related ARDS
Bronchoalveolar neutrophil extracellular trap concentration was not significantly associated with mechanical ventilation duration in pneumonia-related ARDS. The acute respiratory distress syndrome (ARDS) is the most severe... read more
Resuscitation of Endotheliopathy and Bleeding in Thoracic Aortic Dissections
In this randomized, clinical pilot trial of patients undergoing emergency surgery for thoracic aorta dissections, we found that OctaplasLG reduced glycocalyx and endothelial injury, reduced bleeding, transfusions, use of... read more
Research Ethics and Informed Consent in Critical Care
Research studies in critically ill populations pose many unique regulatory and ethical challenges that have implications for study design and execution. The life-threatening nature of conditions being studied and the urgency... read more