Clinical Companion in Nephrology

The second edition of this educational book provides an updated resource on how best to discuss and manage acute and chronic presentations of renal diseases. All chapters have been reviewed and updated to reflect changes... read more

Clinical Companion in Nephrology

Antibiotic prophylaxis reduced broad-spectrum antibiotics and length of stay in ICU patients with alcohol withdrawal induced refractory delirium tremens

Administration of TMP-SMX prophylaxis reduced the use of broad-spectrum antibiotics and ICU LOS in ICU-treated rDT patients. The retrospective study design should be considered when interpreting the results, and prospective... read more

Critical Care Pediatric Nephrology and Dialysis

This book covers all key aspects of critical care in pediatric nephrology, including acute dialysis in sick children. It also provides detailed protocols for managing fluid and electrolyte balance and dialysis in children... read more

Critical Care Pediatric Nephrology and Dialysis

Severe ICU-Acquired Hypernatremia: Prevalence, Risk Factors, Trajectory, Management, and Outcome

Severe hypernatremia occurred in the setting of inability to drink, near-absent measurement of urinary free water losses, diuretic therapy, fever, renal impairment, and near-absent or limited or delayed water administration.... read more

Oxygenation Indices and Early Prediction of Outcome in Hypoxemic Patients with COVID-19 Pneumonia Requiring NIV Respiratory Support in Pulmonary Intermediate Care Unit

Oxygenation indices (OI) showed different effectiveness in predicting NIRT failure within 24 h of treatment in COVID-19 related pneumonia. This may be due to the multi-factorial pathophysiology of hypoxemia. Our study... read more

Awake, Walking, and Intubated – The ICU Breakthrough Giving Patients Their Lives Back

If they knew what it's like for patients surviving after the ICU, that sedation isn't sleep, and that they're being so traumatized and damaged by these normal practices, they would change this. Picture this: it's your... read more

Researchers to Study Online Therapy’s Potential to Prevent Cognitive Decline in ICU Survivors

Researchers from Indiana University Indianapolis, Regenstrief Institute and the IU School of Medicine’s Indiana Alzheimer’s Disease Research Center – led by Babar Khan, M.D., M.S., Sophia Wang, M.D., and Jesse Stewart,... read more

Pitfalls in the Management of Mechanical Ventilation: ARDS and Hypermetabolic States

Mechanical ventilation (MV) is a lifesaving intervention for patients with respiratory failure due to acute respiratory distress syndrome (ARDS) and septic shock. ARDS was first recognized in the late 1960s, approximately... read more

Non-Intensive Care Unit Feasibility for Ambulatory VV-ECMO Patients

Our data suggests that ambulatory veno-venous extracorporeal membrane oxygenation (VV-ECMO) patients may tolerate less than ICU level of care and may even progress to outpatient management as ECMO technology continues to... read more

Make Your Thanksgiving Unforgettable at the Everything-for-Thanksgiving Store!

Forget the last-minute scramble and endless trips—our store is your essential, one-stop destination for a perfect holiday, offering everything from the highest quality heirloom turkeys and fresh, seasonal produce to specialized... read more

Dexmedetomidine for Electroencephalogram in Children with Behavioural Disorders

Intranasal (IN) dexmedetomidine (DEX) is an effective sedative; its recovery time shorter than IV DEX and its favorable adverse events profile make this route a reasonable alternative, especially in pediatric patients with... read more

Impacts of Initial ICU Driving Pressure on Outcomes in Acute Hypoxemic Respiratory Failure

Driving pressure (DP) is a marker of severity of lung injury in patients with acute respiratory distress syndrome (ARDS) and has a strong association with outcome. However, it is uncertain whether limiting DP can reduce... read more

Mitral Valve Transcatheter Edge-to-Edge Repair (MV-TEER) in Patients with Secondary Mitral Regurgitation Improves Hemodynamics, Enhances Renal Function, and Optimizes Quality of Life in Patients with Advanced Renal Insufficiency

Secondary mitral regurgitation (MR) is a common valvular heart disease burdening the prognosis of patients with co-existing chronic heart failure. Transcatheter edge-to-edge mitral valve repair (MV-TEER) is a minimally... read more

Effects of Surgery on Hemodynamics and Postoperative Delirium in Stanford Type A Aortic Dissection

The results of this study indicate that surgical intervention has a significant effect on improving patients’ hemodynamic parameters, with postoperative MAAD and LVEDd reduced compared to preoperative levels, while LVEF... read more

Implementing a Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy Team Reduces Length of Stay and Hospital Costs

Thousands of critically ill patients every year in the United States receive tracheostomy and gastrostomy procedures. Recent research has investigated the benefits of a combined team approach to these procedures, with associated... read more

Predictors of Weaning Failure in Ventilated ICU Patients

Predictors for weaning failure are widely researched. To date, 145 predictors have been investigated with varying intensity in 140 studies that are in line with the current weaning definition. It is no longer just individual... read more

Extended Prone Position and 90-Day Mortality in Mechanically Ventilated Patients with COVID-19

Extended prone positioning (PP) was associated with improved 90-d survival in subjects with COVID-19 undergoing mechanical ventilation for severe ARDS. These findings suggest the potential benefit of EPP in the management... read more

Skin Decontamination to Prevent ICU Infections

Intensive care unit (ICU)-acquired infections can be serious complications of medical care of critically ill patients. Despite multiple tested and implemented preventive measures for such infections, their incidence is persistently... read more

Septic Shock in the Prehospital Setting

Septic shock (SS) is a potential life-threatening condition in which an early identification and immediate therapy stand out as the main cornerstones to improve survival chance; in this context, emergency medical services... read more

Evidence-Based Critical Care

This is the premier evidence-based textbook in critical care medicine. The Third Edition features updated and revised chapters, numerous new references, streamlined content, and new chapters on key topics such as the new... read more

Evidence-Based Critical Care

The Pathophysiology of Happy Hypoxemia in COVID-19

The novel coronavirus disease 2019 (COVID-19) pandemic is a global crisis, challenging healthcare systems worldwide. Many patients present with a remarkable disconnect in rest between profound hypoxemia yet without proportional... read more