Nasotracheal Intubation on Postoperative Neonates with Congenital Heart Disease
Nasotracheal intubation (NTI) is feasible and safe in neonatal cardiac surgery. System-level engagement with stakeholders is necessary to change clinical practice. NTI facilitates early SLP evaluation and treatment and significantly... read more
Trauma, Eighth Edition
Hailed by readers and reviewers for its expert authorship and high-yield clinical content, Trauma is unquestionably the field's definitive text. Enhanced by a full-color design and a high-quality atlas of anatomic drawings... read more
Postoperative Sepsis Infection Can Be Identified Using Gene Expression Signatures
Host biomarker signatures may be able to identify postoperative infection or sepsis up to three days in advance of clinical recognition. If validated in future studies, these signatures offer potential diagnostic utility... read more
Evaluation of an Advanced Critical Care Echocardiography Program
Trainees perceived lack of time and limited access to supervision as major barriers to course completion. Nevertheless, successful portfolio completion was related to factors other than protected time in the echocardiography... read more
CRT-targeted Fluid Resuscitation vs. Lactate-targeted in Septic Shock
Capillary refill time (CRT)-targeted fluid resuscitation in septic shock was not superior to a lactate-targeted one on early fluid administration or fluid balances. However, it was associated with comparable effects on regional... read more
Mental Health Morbidity Among Caregivers
While much of the research on post-ICU mental health morbidity has focused upon the survivors themselves, emerging data shows that caregivers of ICU patients are similarly impacted. The collective sequelae experienced... read more
Public Sepsis Awareness Campaigns Should Be Created Based on Local Data
Although public knowledge of sepsis and its mortality is generally low, some countries have high awareness and knowledge, and as such, any public awareness campaigns should be created based on local data. This will also... read more
Trends in Time to Extubation for Pediatric Postoperative Cardiac Patients
In this large, multicenter database study, early extubation rates in postoperative cardiac patients did not significantly change between 2009 and 2018. Centers that performed early extubation more frequently did not have... read more
MECA in Medical Emergency Situations Significantly Reduced Failure Rates
In our simulation, the use of medical emergency cognitive aid (MECA) in medical emergency situations significantly reduced failure rates. The use of MECA was widely accepted, and MECA were easy to use. In a high percentage,... read more
Optimizing the Design and Analysis of Future AKI Trials
Acute kidney injury (AKI) is a complex clinical syndrome associated with an increased risk of morbidity and mortality, particularly in critically ill and perioperative patient populations. Most AKI clinical trials have... read more
Fear and Insight in the ICU Bed
Mid-morning dressing changes, hours wasted, going through each cut methodically. Dressing off, wound cleaned, redressed. The brunt of pain dealt with by nature before giving in. The intensive care unit (ICU) nurse offers... read more
Feelings of Strangeness in ICU Patients
After several weeks in the intensive care unit (ICU) following a lung infection, Mr Pol wakes up from a coma and gradually becomes aware of his situation. The healthcare team rejoice in the successful outcome of his extubation:... read more
Intravenous Tenecteplase vs. Alteplase for Acute Ischemic Stroke
Between Dec 10, 2019, and Jan 25, 2022, 1,600 patients were enrolled and randomly assigned to tenecteplase (n=816) or alteplase (n=784), of whom 1577 were included in the intention-to-treat (ITT) population (n=806 tenecteplase;... read more
Evolving Crisis Standards of Care and Ongoing Lessons from COVID-19
Crisis Standards of Care (CSC) inform decisions on medical care during a large-scale crisis such as a pandemic or natural disaster, eliminating the need to make these decisions at the bedside without protections or guidance.... read more
