Priorities in Critical Care Nursing
With its succinct coverage of all core critical care nursing topics, this evidence-based text is the perfect resource for both practicing nurses and nursing students alike. Using the latest, most authoritative research, this... read more
Opioid Use After Intensive Care
Mean opioid consumption is increased 24 months after ICU admission despite the lack of evidence for long-term opioid treatment. Given the high number of ICU entries and risk of excess mortality for chronic users, preventing... read more
Inflammatory Response and Phenotyping in SARI From the MERS Coronavirus
One third of critically ill patients with Middle East respiratory syndrome (MERS) severe acute respiratory infection (SARI) and non-Middle East respiratory syndrome severe acute respiratory infection demonstrated a subphenotype... read more
Ultrasound Program Management
A Comprehensive Resource for Administrating Point-of-Care, Emergency, and Clinical Ultrasound. This book addresses the wide range of issues that face the program leader – from how to choose a site and how to negotiate for... read more
Association between the BMI and outcomes of patients resuscitated from OHCA
The body mass index (BMI) was not independently associated with favourable neurologic and survival outcomes of patients surviving from out-of-hospital cardiac arrest (OHCA). Nine hospitals were enrolled; finally, 605 patients... read more
Janssen Investigational COVID-19 Vaccine
An investigational COVID-19 vaccine developed by Janssen Pharmaceuticals appears to be safe and effective at preventing moderate and severe COVID-19 in adults, according to an interim analysis of Phase 3 clinical data conducted... read more
Contrast-enhanced Ultrasound (CEUS) of the Lung Reveals Multiple Areas of Microthrombi in a COVID-19 Patient
Peng et al. have outlined several characteristics common to all COVID-19 patients using lung ultrasound and the 12 zone method. Zotzmann et al. in a follow-up letter raised the question on whether these areas of subpleural... read more
Targeting MAP in Sepsis
What’s your target mean arterial pressure (MAP) for patients with sepsis? Do you believe in the magic number of 65? What about those patients with chronic hypertension? What about when there is no evidence of end organ... read more
Delirium Incidence, Duration, and Severity in Critically Ill Patients with COVID-19
Delirium without coma occurred in 29.1% of patients admitted to the ICU. Delirium persisted for a median of 5 days and was severe. Mechanical ventilation was significantly associated with odds of delirium even after adjustment... read more
Timing, Outcome, and Risk Factors of Intracranial Hemorrhage in ARDS Patients During VV-ECMO
Intracranial hemorrhage occurs early during venovenous extracorporeal membrane oxygenation (VV-ECMO) and is a determinant for 60-day mortality. Appropriate adjustment of identified modifiable risk factors might lower... read more
Effectiveness of Bundle Interventions on ICU Delirium
This meta-analysis fails to support that bundle interventions are effective in reducing ICU delirium prevalence and duration, but supports that bundle interventions are effective in reducing the proportion of patient-days... read more
Perspectives of Ketamine Use in COVID-19 Patients
Hospitalized coronavirus disease 2019 (COVID-19)-infected patients suffer from both physical impairments and mental stress. Respiratory insufficiency and cardiovascular disturbances require most of the intensive care... read more
Mortality of Older Patients Admitted to an ICU
In this systematic review of older patients admitted to intensive care, we have documented substantial variation in short- and long-term mortality as well as in prognostic factors evaluated. To better understand this... read more
Let’s stop the blame game over the ICU beds shortage for COVID-19 patients
The situation in UK intensive care units (ICUs) is grave. Across the UK, units are under immense pressure and are as busy or busier than they were in the first wave. All plans enacted over the summer to provide support for... read more
Allergic Reactions After First Dose of Pfizer-BioNTech COVID-19 Vaccine
Anaphylactic reactions to the first dose of the Pfizer-BioNTech COVID-19 vaccine are rare, usually occur within 30 minutes of administration, and are readily treatable. From December 14-23, 2020, following administration... read more
High-dose Vitamin C in Critically Ill COVID-19 Patients
This pilot trial showed that high-dose intravenous vitamin C (HDIVC) failed to improve IMVFD28, but might show a potential signal of benefit in oxygenation for critically ill patients with COVID-19 improving PaO2/FiO2 even... read more
Barriers to reporting guideline adherence in POCUS research
Although investigators and editors recognise the importance of completely reported research, reporting quality is still a core issue for point-of-care ultrasound (POCUS) research. The shared opinion held by investigators... read more
Subtle Presentations of Shock in the ED Setting
The patient was a 2-year-old female with a history of allergy to peanuts who was brought to the emergency department by her mother because of a complaint of allergic reaction. Twenty minutes prior to arrival, the patient... read more
Colchicine, the only effective oral medication for treating non-hospitalized COVID-19 patients
The Montreal Heart Institute announced COLCORONA clinical trial has provided clinically persuasive results of colchicine's efficacy to treat COVID-19. The study results show that colchicine reduces the risk of death or... read more
Prone Positioning Non-intubated COVID-19 Patients with Severe Hypoxemia Was Safe
In a small sample, prone positioning non-intubated COVID-19 patients with severe hypoxemia was safe; however, many patients did not tolerate prolonged durations. Although patients had improved oxygenation and respiratory... read more
Full-dose blood thinners decreased need for life support and improved outcomes in COVID-19 patients
Full dose anticoagulation (blood thinner) treatments given to patients hospitalized for COVID-19 reduced the requirement of vital organ support in a large clinical trial conducted worldwide. With large numbers of COVID-19... read more
RAPID UPDATE: Clinical Guide for the Management of Critical Care for Adults with COVID-19
This RAPID UPDATE to the FICM/ICS "Clinical guide for the management of critical care for adults with COVID-19 during the Coronavirus pandemic" highlights five clinically urgent issues for practising clinicians caring for... read more
