Tag: blood
Platelet Transfusions: Ten Things ICU Specialists Need to Know
Thrombocytopenia is common in critically ill patients and is associated with higher bleeding risk and worse outcomes. Platelet transfusions are frequently used to prevent or treat bleeding, though often with uncertain... read more
Introduction to Hemodynamics
This book presents a bibliographical work on the modeling of blood dynamics. The first chapter describes the anatomy of the cardiovascular system and the functioning of the blood circulation. The second chapter is devoted... read more
High Speed Blood Flow Measurements Enabled by LW-iDCS
In this work we have demonstrated the development of long wavelength, interferometric diffuse correlation spectroscopy. Using a fiber optic probe with collocated detection fibers, we were able to directly compare measured... read more
No Benefits For Using 4-Factor Prothrombin Complex Concentrate (4F-PCC) in Trauma Patients
Early administration of 4-factor prothrombin complex concentrate (4F-PCC) was of no benefit to patients with trauma at risk of massive transfusion, the randomized PROCOAG trial from France showed. Among over 300 patients... read more
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitated from cardiac arrest did not result in significantly different percentages of patients dying or having severe disability... read more
Trauma-induced Coagulopathy
Trauma is a major cause of mortality worldwide, and bleeding is the leading preventable cause of death. About one-quarter of patients with severe trauma develop a clotting disorder termed trauma-induced coagulopathy (TIC)... read more
Economical provision of blood components for critical patient transport across a large geographic area
With appropriate attention to detail, it is possible to provide life-saving blood components to aeromedical transport services across a large geographic area with efficient blood component usage, minimal blood wastage, and... read more
Combined Platelet and Erythrocyte Salvage: Evaluation of a New Filtration-based Autotransfusion Device
This study demonstrated the performance of the SAME device. Platelets and red blood cells were salvaged without significant impact on cell integrity and function. In the meantime, leukocytes were not activated, and the washing... read more
COVID-19: Convalescent Plasma vs. Standard Plasma
Administration of convalescent plasma to hospitalized patients with coronavirus disease 2019 infection increased antibodies to severe acute respiratory syndrome coronavirus disease 2 but was not associated with improved outcome. Enrollment... read more
Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid
Combinations of coagulation factor concentrates suspended in albumin solutions can restore thromboelastometry parameters in the absence of plasma. This kind of artificial colloid fluids with coagulation-restoring characteristics... read more
The Blood-Clot Problem Is Multiplying
For weeks, Americans looked on as other countries grappled with case reports of rare, sometimes fatal blood abnormalities among those who had received the AstraZeneca vaccine against COVID-19. That vaccine has not yet... read more
Early Hemostatic Management of Disseminated Intravascular Coagulopathy
Inflammation and coagulation pathobiology play a significant role in the development of multiorgan failure occurring with sepsis. Inflammation induced by an infection can lead to endothelial injury, which subsequently... read more
COVID-19 Blood Plasma Trial Finds No Benefit in Severely Ill Patients
An international trial testing convalescent blood plasma on COVID-19 patients with moderate and severe illness has halted enrolment of severely ill COVID-19 patients requiring intensive care after it found no benefit. The... read more
NIH ACTIV trial of blood thinners pauses enrollment of critically ill COVID-19 patients
Three clinical trial platforms working together to test the effects of full doses of anticoagulants (blood thinners) in COVID-19 patients have paused enrollment for one group of patients. Among critically ill COVID-19... read more
Pulse Oximeter Devices Have Higher Error Rate in Black Patients
A study showed that the devices, which measure oxygen levels in the blood, were three times more likely to give misleading readings among African-American patients. Pulse oximeters are one of the most commonly used tools... read more
