Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

We present a case of 43-year-old male patient with broadly by Omalizumab, Mepolizumab and Benralizumab pretreated allergic asthma, who suffered a near fatal exacerbation, triggered by an influenza A infection. Due to... read more

A nomogram predicting pneumonia after cardiac surgery

A nomogram predicting pneumonia after cardiac surgery

Three preoperative indicators (age, preoperative malnutrition, diabetes mellitus), one intraoperative indicator (CPB > 135 min) and three postoperative indicators (moderate to severe ARDS, use of ECMO or IABP or CRRT, MV>... read more

Prone Positioning During ECMO for Severe ARDS

Prone Positioning During ECMO for Severe ARDS

The ongoing debate on optimal extracorporeal membrane oxygenation (ECMO) care emphasizes the need for rigorous investigation, acknowledging the value of observational data in routine The PRONECMO study, with its pragmatic... read more

Managing the Cerebral Complications of ARDS

Managing the Cerebral Complications of ARDS

Acute respiratory distress syndrome (ARDS) comprises 10–30% of critical care admissions worldwide. ARDS outcomes have improved secondary to ventilatory strategies that may potentially mitigate ventilator-induced lung injury.... read more

Nursing Care and ECMO

Nursing Care and ECMO

This highly informative book provides essential insights for ICU nurses at ECMO centers around the world, who face the substantial challenges involved in the management of ECMO patients. Above all, it meets their training... read more

ARDS Guidelines: Oceans Apart or Rivers That Merge?

ARDS Guidelines: Oceans Apart or Rivers That Merge?

The updated guidelines from the ATS and ESICM reached overwhelmingly similar conclusions. Both sets of guidelines emphasize the challenges in issuing blanket recommendations that apply to all patients with ARDS, and both... read more

Extracorporeal Life Support: The ELSO Red Book, 6th Edition

Extracorporeal Life Support: The ELSO Red Book, 6th Edition

Written by over two hundred experts from around the world, this new edition is the definitive reference text on Extracorporeal Life Support, providing both the latest evidence and practical advice on how to clinically manage... read more

Extracorporeal Life Support for Adults

Extracorporeal Life Support for Adults

This book presents a concise, evidence-based review of extracorporeal life support (ECLS) for adult diseases. It describes the use of ECLS with patients who are experiencing severe hypoxemic respiratory failure (ARDS and... read more

Platelets and Fibrinogen Matter When Bleeding on ECMO

Platelets and Fibrinogen Matter When Bleeding on ECMO

Fibrinolysis is poorly investigated in ECMO patients, partly due to a lack of routine laboratory tests evaluating fibrinolysis. Hence, hyperfibrinolysis may be a contributor to bleeding risk during ECMO treatment. However,... read more

ECPR in 2023

ECPR in 2023

Extracorporeal cardiopulmonary resuscitation (ECPR) is invasive and resource intense. Data suggesting a survival benefit in patients after OHCA and ECPR derive from retrospective registries and meta-analyses. In order to... read more

Propofol-Related Infusion Syndrome in a Child with RSE

Propofol-Related Infusion Syndrome in a Child with RSE

Propofol is used for sedation, anxiolysis, anesthesia induction, and as an anticonvulsant. In cases of refractory status epilepticus (RSE), propofol is more efficient than barbiturates. We present a case of a 3-year-old... read more

Age and Associated Outcomes Among Patients Receiving V-A ECMO

Age and Associated Outcomes Among Patients Receiving V-A ECMO

In a multinational study using the ELSO Registry, we found that increasing age was strongly associated with higher risk of hospital mortality and complications among patients receiving V-A ECMO for cardiogenic shock, with... read more

ECMO-Extracorporeal Life Support in Adults

ECMO-Extracorporeal Life Support in Adults

Extracorporeal membrane oxygenation (ECMO) has been in clinical use for some 40 years, but it is only in the past decade that its application in the treatment of life-threatening circulatory and respiratory failure has truly... read more

Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

Revisiting VA-ECMO in Infarct-related Cardiogenic Shock

Despite advances in medical therapies and coronary revascularization, infarct-related cardiogenic shock remains a life-threatening emergency with high death rates. Temporary mechanical circulatory support, including peripheral... read more

Using Deep Neural Networks for Survival Prediction in VA-ECMO

Using Deep Neural Networks for Survival Prediction in VA-ECMO

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a complex and high-risk life support modality used in severe cardiorespiratory failure. ECMO survival scores are used clinically for patient prognostication... read more

Anticoagulation in the ICU: Contact Pathway Inhibition Future

Anticoagulation in the ICU: Contact Pathway Inhibition Future

Bleeding and thrombotic complications are the main cause of morbidity and mortality in critically ill patients on the intensive care unit (ICU), receiving short-term percutaneous mechanical circulatory support (pMCS) by extracorporeal... read more