Nasotracheal vs. Orotracheal Intubation for Sedation in Critically Ill Patients

Nasotracheal vs. Orotracheal Intubation for Sedation in Critically Ill Patients

Nasotracheal intubation (NTI) may be used for long term ventilation in critically ill patients. Although tracheostomy is often favored, NTI may exhibit potential benefits. Compared to orotracheal intubation (OTI), patients... read more

Effect of Antimicrobial De-escalation Strategy on 14-day Mortality Among ICU Patients

Effect of Antimicrobial De-escalation Strategy on 14-day Mortality Among ICU Patients

The prevalence of antimicrobial de-escalation (ADE) strategy was low among intensive care unit patients. The ADE strategy demonstrated a protective effect or no adverse effect on 14-day mortality compared to the No Change... read more

Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery

Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery

Right ventricular failure (RVF) is a leading driver of morbidity and mortality after major cardiac surgery for advanced heart failure, including orthotopic heart transplantation and left ventricular assist device implantation.... read more

Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension

Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension

In this prospective study of children who received CPR in intensive care units, a pre-existing diagnosis pulmonary hypertension was present in 16% of children but was not associated with statistically significant differences... read more

Optimal Fluid Therapy for Sepsis Management in Critically Ill Adults

Optimal Fluid Therapy for Sepsis Management in Critically Ill Adults

For a study, researchers aimed to analyze the fluid treatment in septic critically ill adults. About 20% to 30% of patients were admitted to an ICU with sepsis. In sepsis patients, investigators observed intravenous fluid... read more

Propofol in ICU Settings: Understanding and Managing Anti-Arrhythmic, Pro-Arrhythmic Effects, and Propofol Infusion Syndrome

Propofol in ICU Settings: Understanding and Managing Anti-Arrhythmic, Pro-Arrhythmic Effects, and Propofol Infusion Syndrome

Propofol has revolutionized anesthesia and intensive care medicine owing to its favorable pharmacokinetic characteristics, fast onset, and short duration of action. This drug has been shown to be remarkably effective in numerous... read more

Severe Hypertriglyceridemia: A 10-Year Review

Severe Hypertriglyceridemia: A 10-Year Review

This study shows the morbidity profile associated with severe hypertriglyceridemia (SHTG), with a high level of ICU admissions and also a high level of the use of plasmapheresis. In our population, this approach had good... read more

Every Deep-Drawn Breath: A Critical Care Doctor on Healing, Recovery, and Transforming Medicine in the ICU

Every Deep-Drawn Breath: A Critical Care Doctor on Healing, Recovery, and Transforming Medicine in the ICU

A world-renowned critical care doctor offers hope for ICU patients and their families in this timely, urgent, and compassionate narrative. Over the next ten years, 40 to 60 million people in this country will be admitted... read more

ICU Delirium – A Decade of Learning

ICU Delirium – A Decade of Learning

Think of delirium as the phenotypic manifestation of global, acute brain dysfunction that can deprive patients of their dignity. This syndrome of acute changes in awareness, attention, and cognition is an independent... read more

Pulmonary Artery Catheter Use and Mortality in the Cardiac ICU

Pulmonary Artery Catheter Use and Mortality in the Cardiac ICU

The appropriate use of pulmonary artery catheters (PACs) in critically ill cardiac patients remains debated. There is wide variation in the use of PACs that is not fully explained by patient level-factors and appears driven... read more

Acute Kidney Injury in ICU Patients

Acute Kidney Injury in ICU Patients

Patients admitted to the intensive care unit are prone to various complications, one of which is acute kidney injury (AKI). The etiology of acute kidney injury can be multifactorial. Among the various causes, sepsis remains... read more

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Balloon therapy is an empirical example that patients with respiratory tract diseases can use to improve their daily care. The diaphragm and ribs are expanded and raised by the intercostal muscles, which are activated during... read more

Bronchoscopy in ICU: A Practical Guide

Bronchoscopy in ICU: A Practical Guide

This practical guide focuses on Bronchoscopy in ICU. Bronchoscopy is one of the most commonly performed medical procedures, but is limited to the practice of a handful chest physicians and surgeons. The field of bronchoscopy... read more

Why We Can Thank a Polio Emergency for the Birth of Intensive Care

Why We Can Thank a Polio Emergency for the Birth of Intensive Care

An outbreak of polio in 1950s Denmark led one hospital to pioneer mechanical ventilation, constant monitoring of vital signs and other innovations that are saving lives to this day. The COVID-19 pandemic has brought home... read more

Comparison of ETA and BALF mNGS in Severe Pneumonia

Comparison of ETA and BALF mNGS in Severe Pneumonia

Our study showed that some differences in the microbiological diagnosis via endotracheal aspirate (ETA) mNGS and bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) appear to exist. Clinicians... read more

Increased Fungal Infections Hospitalizations during COVID-19

Increased Fungal Infections Hospitalizations during COVID-19

An examination of a large healthcare database in the United States revealed a significant rise in hospitalization rates related to fungal infections between 2019 and 2021. This increase was primarily driven by hospitalizations... read more

Mechanical Ventilation in Emergency Medicine

Mechanical Ventilation in Emergency Medicine

This book discusses mechanical ventilation in emergency settings, covering the management of patients from the time of intubation until transfer to the ICU. It provides an introduction to key concepts of physiology pertinent... read more