Tag: ICU
Weaning Failure Prediction Using Electrocardiographic Time-frequency Analysis and Respiration Flow Signals
Weaning patients from mechanical ventilation (MV) is a crucial process that requires meticulous assessment of their ability to breathe independently without ventilatory assistance. Spontaneous breathing test (SBT) is... read more
Anesthesia Role in Sedation and Weaning From Mechanical Ventilation
This systematic review highlights the advantages of anesthetic sedation strategies, particularly the use of dexmedetomidine, methadone, or sequential sedation protocols, in improving weaning outcomes, enhancing sedation quality,... read more
Dexmedetomidine Use for Palliative Sedation in Non-ICU Settings
Dexmedetomidine is a promising adjunct to be considered for palliative sedation when managing end-of-life symptoms such as refractory pain, anxiety, or delirium. This medication should be considered a reasonable alternative... read more
Clinical Characteristics and Survival Outcomes of Invasive Pulmonary Aspergillosis Patients
Invasive pulmonary aspergillosis (IPA) is a severe infectious disease caused by Aspergillus spp. It is associated with high mortality, particularly in immunocompromised patients, as well as in those with COVID-19 pneumonia... read more
Baricitinib Use in Children with Severe COVID-19 Infection
Baricitinib appears safe for both immunocompetent and immunocompromised children hospitalized for severe COVID-19. Most adverse events did not inhibit therapy administration, and there were no deaths following the initiation... read more
Analgosedation Practice During Noninvasive Respiratory Supports
Sedation is frequently used in patients with acute respiratory failure (ARF) undergoing Noninvasive Respiratory Supports (NRSs). Current analgesic practices are becoming more standardized, with analgosedation strategies increasingly... read more
Lung-protective Ventilation Strategies for Mechanical Ventilation
This study is an important step toward optimizing mechanical ventilation strategies, addressing the interplay between mechanical power, gas exchange and long-term respiratory outcomes could further refine lung-protective... read more
Early Initiated Noradrenaline vs. Fluid Therapy for Hypotension and Shock
The VASOSHOCK trial is a pragmatic, multi-center, superiority, randomized controlled trial investigating early initiation of peripheral noradrenaline in hypotension and shock, investigating the impact of this treatment on... read more
Severe Adenoviral Infections: Disease Progression and Poor Prognostic Markers
Low hemoglobin, high serum ferritin, and high LDH in the second week are markers of disease progression and poor prognostic markers in severe adenoviral infections, emphasizing further research and targeted interventions. The... read more
Increased Sodium Levels Associated with Ceftriaxone Administration
Serum sodium elevation is considered a frequent manifestation in critically ill patients, with significant clinical outcomes and requiring timely management. This case report suggests a possible association between the... read more
Dynamic Left Ventricular Outflow Tract Obstruction Induced by IABP in Patient with Angioedema
Mechanical circulatory support with intra-aortic balloon pump (IABP) can aid in the treatment of cardiogenic shock but may rapidly become detrimental due to the reduction in systolic arterial afterload in patients with predispositions... read more
Glycemic Control Role in Inflammation Markers and Clinical Outcomes in Type 2 Diabetes Patients with Severe COVID-19
This study demonstrates that among hospitalized COVID-19 patients with type 2 diabetes mellitus, poor glycemic control (HbA1c ≥ 7%) correlates with increased systemic inflammation, greater disease severity, and worse clinical... read more
Management of ARDS COVID-19 Patients Using Hemoperfusion and CRRT
Combined hemoperfusion (HP) and continuous renal replacement therapy (CRRT) hold promise as a potential intervention for severe COVID-19 cases with multiple organ dysfunction, leading to improved clinical outcomes. Fifty-six... read more
VAP Recurrences Definition: European Experts Consensus
This consensus by European experts proposes four different ventilator-associated pneumonia (VAP) recurrence entities which should facilitate the harmonization of recurrence criteria for clinical practice and future studies. Thirty-six... read more
Septic Shock Metabolic Subgroups and Clinical Outcome
Three metabolic clusters exist in patients with septic shock with most metabolites differing between clusters and lipid species being most influential. Cluster proportions evolved over time with a high metabolite group... read more
VA-ECMO and Pulmonary Reperfusion
The study by Stadlbauer and colleagues provides further evidence that veno-arterial extracorporeal membrane oxygenation (VA-ECMO) should—whenever necessary—be used, as a bridge to pulmonary reperfusion, but not as a bridge... read more
Continuous Glucose Monitoring-Based Insulin Titration Protocol for Type 2 Diabetes Patients
The continuous glucose monitoring (CGM)-based insulin titration protocol by Olsen et al has been successfully implemented for titrating basal, prandial, and correctional insulin in inpatients with type 2 diabetes in non-ICU... read more
Fluid Management Impact on Outcomes in Sequential Extracorporeal Support
Sepsis is a life-threatening condition characterized by dysregulated inflammatory responses, often leading to multiple organ dysfunction and high mortality rates. Continuous renal replacement therapy (CRRT) and extracorporeal... read more
Leptin and Linterlukin-6 Relationship and Influence of Mortality in Sepsis
High leptin levels might counteract the adverse prognostic effect of elevated IL-6 on septic mortality. At the same IL-6 level, leptin could predict septic mortality. Leptin might be a protecting factor for men and gender-different... read more
TyG Index And Short-term Mortality in Patients with Cardiogenic Shock
The triglyceride-glucose (TyG) index is significantly associated with short-term mortality in patients with cardiogenic shock (CS) and may serve as a useful biomarker for risk stratification. This retrospective cohort... read more
Promising Prognostic Predictors in Sepsis Patients Using Lactate and Albumin Ratio
Serum Lactate/Albumin ratio and BAR ratio were significantly higher in sepsis and/or septic shock and associated with increased length of hospital stay and increased in-hospital mortality and poor clinical outcome inside... read more
VAP in Patients with Increased Intra-abdominal Pressure
Critically ill patients with increased intra-abdominal pressure (IAP) and multidrug-resistant (MDR) ventilator-associated pneumonia (VAP) are considered a challenging patient population in every ICU setting. Patients with... read more
