Tag: mortality

Beta-Blocker Therapy in Severe TBI

Propranolol decreases in-hospital mortality and improves long-term functional outcome in isolated severe Traumatic Brain Injury (TBI). This randomized trial speaks in favor of routine administration of beta-blocker therapy... read more

Neuroprognostication Practices in Postcardiac Arrest Patients

Neuroprognostic approaches to hypoxic-ischemic encephalopathy vary among physicians and are often not consistent with current guidelines. The overall inconsistency in approaches and deviation from evidence-based recommendations... read more

Blood Transfusion – Fresh vs. Standard-issue in Critically Ill Pediatric Patients

Among critically ill pediatric patients, the use of fresh red blood cells did not reduce the incidence of new or progressive multiple organ dysfunction syndrome (including mortality) compared with standard-issue red blood... read more

Frailty Predicts 30-day Mortality in Intensive Care Patients

Premorbid frailty was common in general ICU patients and was an independent predictor of death. Our study suggests that frailty could be a valuable addition in outcome prediction in intensive care. The receiver operating... read more

Risk Factors for the Development of ARDS in Mechanically Ventilated Adults in Peru

In this study of mechanically ventilated patients, 31% of study participants had acute respiratory distress syndrome (ARDS) at some point during their ICU stay. Optimal lung-protective ventilation was not used in a majority... read more

Maternal Risk Modeling in Critical Care

Risk prediction models specific to the maternal critical care population was developed. The models compare favorably against general adult ICU risk prediction models in current use within this population. The aim was to... read more

Impact of Levosimendan on Weaning from Peripheral VA-ECMO in ICU

This study suggests that levosimendan might be associated with a beneficial effect on venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in ICU patients. The difference in mortality among propensity-matched... read more

Prehospital On-scene Anesthetist Treating Severe TBI Patients is Associated with Lower Mortality and Better Neurological Outcome

Patients with isolated traumatic brain injury (TBI) are likely to benefit from effective prehospital care to prevent secondary brain injury. Only a few studies have focused on the impact of advanced interventions in TBI... read more

Sepsis Kills Twice as Many People as Experts Feared

Sepsis, which is triggered by an infection, is the cause of 1 in 5 deaths worldwide. It is thought to have killed 47,860 in 2017 - ranking us 45th worst out of 195 countries. Researchers estimate the condition claimed... read more

Study Suggests Benefits of Vitamin C for Severe Sepsis

More than 1.7 million Americans develop sepsis every year and incidence of the condition is on the rise. In severe cases, widespread inflammation leads to multiorgan failure and death. Results of a new study hold... read more

Is Intensive Care Becoming an Out-of-hours Acute Palliative Care Service?

First I will define what I conceive medicine to be. In general terms, it is to do away with the sufferings of the sick, to lessen the violence of their diseases, and to refuse to treat those who are overmastered by their... read more

Lower Glucose Targets Show Improved Mortality in Cardiac Patients

Tighter glucose control while minimizing the risk of severe hypoglycemia is associated with lower mortality among critically ill cardiac patents, new research suggests. Researchers reported in CHEST on the outcomes of... read more

Serum Lactate Level and Mortality in Metformin-associated Lactic Acidosis Requiring RRT

This study suggests that predialysis level of serum lactate level is an important marker of mortality in MALA patients requiring renal replacement therapy (RRT) with a linear dose-response relationship. To better evaluate... read more

Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus Aureus Bacteremia

The results of this study further support the importance of prompt appropriate antibiotic administration for patients with septic shock. Physicians should consider acting quickly to administer antibiotics with S. aureus... read more

ICU Bouncebacks Associated with Worse Outcomes

ICU Bouncebacks (ICUBBs) are associated with worse outcomes and are disproportionately burdened by respiratory complications. These findings emphasize the importance of the TQIP Collaborative in identifying statewide... read more

Improving Community Recognition of Sepsis Using Early Warning Scores

Introducing a community version of National Early Warning Score (NEWS) to clinical assessments in acute clinical care has shown benefits for both patients and staff, and could be disseminated to all community services across... read more

Time to Treatment and Mortality during Mandated Emergency Care for Sepsis

More rapid completion of a 3-hour bundle of sepsis care and rapid administration of antibiotics, but not rapid completion of an initial bolus of intravenous fluids, were associated with lower risk-adjusted in-hospital mortality. Among... read more

Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a PICU

Greater numbers of severe hyperoxemia events appeared to be associated with increased mortality in this large, diverse cohort of critically ill children, supporting a possible exposure-response association between severe... read more

Defining Benefit Threshold for ECMO in Children with Sepsis

This binational study demonstrates that a rapidly available sepsis mortality prediction model can define thresholds for survival benefit in children with septic shock considered for ECMO. Survival on ECMO was associated... read more

Differential Gene Expression in Peripheral White Blood Cells with Permissive Underfeeding and Standard Feeding in Critically Ill Patients

The effect of short-term caloric restriction on gene expression in critically ill patients has not been studied. In this sub-study of the PermiT trial, we examined gene expression patterns in peripheral white blood cells... read more

Influence of Dyskalemia at ICU Admission and Early Dyskalemia Correction on Survival

Dyskalemia is common at ICU admission and associated with increased mortality. Occurrence of cardiac events increased with dyskalemia depth. A correction of serum potassium level by day 2 was associated with improved... read more

Effects of Sepsis on Mortality in Critically Ill Patients 2 Years After ICU Discharge

Compared with patients without sepsis, those with sepsis have higher mortality in the intensive care unit and have more pain, hospital readmissions, and functional decline within 2 years after discharge. During the study,... read more