Tag: oxygenation
Prone Position Minimizes the Exacerbation of Effort-dependent Lung Injury
Prone position, independent of positive end-expiratory pressure levels, diminishes a maldistribution of lung stress and inflation imposed by spontaneous effort and mitigates spontaneous effort, resulting in less effort-dependent... read more
HFNO Alone or Alternating with NIV in ARF Patients
In critically ill immunocompromised patients with acute respiratory failure (ARF), the mortality rate did not differ between HFNO alone and non-invasive ventilation (NIV) alternating with high-flow nasal oxygen (HFNO). However,... read more
90% of ECMO-eligible COVID-19 Patients Died Amid Rationing
Nearly 90% of adult COVID-19 patients who were eligible for—but didn't receive—extracorporeal membrane oxygenation (ECMO) during the height of the pandemic died in the hospital owing to a lack of resources, even though... read more
Optimal Respiratory Support for COVID-19 Patients
Noninvasive respiratory support is an essential component of critical care. Both noninvasive ventilation, with its different interface types and modes (including helmet and face masks), and high-flow nasal oxygen (HFNO) are... read more
Physiologically Difficult Airway Evaluation
Multiple international airway societies have created guidelines for the management of the difficult airway. In critically ill patients, there are physiologic derangements beyond inadequate airway protection or hypoxemia.... read more
Fluid Balance and Ventilator-Associated Events Among Patients Admitted to ICUs in China
There was nonlinear relationship between fluid balance and all three tiers of ventilator-associated event, with an fluid balance between –1 and 0 L corresponding to the lowest risk. Positive but not negative fluid balance... read more
Liberation from Invasive Mechanical Ventilation with Continued Receipt of Vasopressor Infusions
Weaning protocols for discontinuation of invasive mechanical ventilation often mandate resolution of shock. Whether extubation while receiving vasopressors is associated with harm is uncertain. To examine whether extubation... read more
Treating Hypoxia in Discharged COVID-19 Patients
The ICU technique of placing a hypoxic patient in a prone position is being widely used to care for COVID-19 patients in respiratory distress to improve oxygenation and possibly to avoid intubation. The COVID-19 pandemic... read more
Bivalirudin vs. Heparin for Maintenance Systemic Anticoagulation During ECMO
When compared with heparin-based systemic anticoagulation, bivalirudin demonstrated feasibility and safety as established by the absence of increases in identifiable adverse outcomes while manifesting substantial improvements... read more
Study Supports Remdesivir Treatment for COVID-19 Patients on Low-Flow Oxygen or No Oxygen
Remdesivir treatment increased the likelihood of clinical improvement in COVID-19 patients on low-flow oxygen or no oxygen, according to a new study by the Johns Hopkins University School of Medicine, the Johns Hopkins Bloomberg... read more
Transtracheal Jet Ventilation in the Can’t Intubate Can’t Oxygenate Emergency
Transtracheal jet ventilation (TTJV) is associated with a high risk of device failure and barotrauma in the CICO emergency. Guidelines and recommendations supporting the use of TTJV in CICO should be reconsidered. 44 studies... read more
Subclavian vs. Femoral Arterial Cannulations During ECMO
During peripheral extracorporeal veno-arterial membrane oxygenation (VA-ECMO) support, subclavian arterial cannulation provides, in comparison to femoral arterial cannulation, an anterograde flow which may prevent from left... read more
Energy Transmission in Mechanically Ventilated Children
Mechanical energy (ME) better related to underlying lung pathology and patient outcome than MP. The delivery of generated energy to the lung was not dependent on endotracheal tube diameter (ETT) size during PC ventilation.... read more
Association of Volume Status During VV ECMO with Outcome
Fluid overload in acute respiratory distress syndrome is associated with increased mortality. The purpose of this study was to investigate the association of cumulative fluid balance (CFB) during the first 7 days of eno-venous... read more
Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19
An overall good trial that supports the use of high flow oxygen therapy in patients with Severe COVID-19. Randomized controlled trial conducted across three centers in Columbia over 5 months from August 2020 to January... read more
Respiratory Drive in Sepsis and Septic Shock Patients: Modulation by High-flow Nasal Cannula
Patients with sepsis and septic shock of extrapulmonary origin present elevated respiratory drive and effort, which can be effectively reduced by high-flow nasal cannula. 25 nonintubated patients with extrapulmonary sepsis... read more
Ventilation in Patients with Intra-abdominal Hypertension
The incidence of intra-abdominal hypertension (IAH) is high and still underappreciated by critical care physicians throughout the world. One in four to one in three patients will have IAH on admission, while one out of... read more
Intubation Practice and Outcomes Among Pediatric Emergency Departments
While tracheal intubation (TI) characteristics vary between pediatric Emergency Departments and ICUs, outcomes are similar. Shock and limited mouth opening were independently associated with adverse TI events in the Emergency... read more
High-Flow Oxygen Therapy vs. Conventional Oxygen Therapy on Invasive Mechanical Ventilation in COVID-19 Patients
Among patients with severe COVID-19, use of high-flow oxygen through a nasal cannula significantly decreased need for mechanical ventilation support and time to clinical recovery compared with conventional low-flow oxygen... read more
Non-invasive vs. Invasive Respiratory Management Strategies in AHRF Patients
When performing non-invasive ventilation among patients with de novo acute hypoxaemic respiratory failure (AHRF), it is important to avoid excessive tidal volume and lung injury. Although pressure support is needed for... read more
Oxygenation Responses Mechanisms to Proning and Recruitment in COVID-19 Pneumonia
In unresolving COVID-19 pneumonia, the respiratory mechanics and the gas-exchange response to prone positioning and recruitment largely depend on the following two factors: perfusion dysregulation and the amount of consolidated... read more
The Pulmonary Artery Catheter: A Solution Still Looking For a Problem
In 1970, Jeremy Swan, William Ganz, and colleagues published their seminal paper “Catheterization of the heart in man with use of flow-directed balloon-tipped catheter”. Few devices in our specialty have generated more... read more
