Prone Positioning Effect on Adult Patients Survival Receiving vvECMO for ARDS

Prone Positioning Effect on Adult Patients Survival Receiving vvECMO for ARDS

This systematic review and meta-analysis of 13 studies (total N = 1836) showed that PP of acute respiratory distress syndrome (ARDS) patients receiving venovenous ECMO (vvECMO) was associated with a significant improvement... read more

A New Risk Assessment Model for Hospital-Acquired Venous Thromboembolism in Critically Ill Children

A New Risk Assessment Model for Hospital-Acquired Venous Thromboembolism in Critically Ill Children

Using the multicenter Children’s Hospital-Acquired Thrombosis registry, we identified five independent risk factors for hospital-acquired venous thromboembolism in critically ill children, deriving a new hospital-acquired... read more

Saline vs. Balanced Crystalloid in Patients with Diabetic Ketoacidosis

Saline vs. Balanced Crystalloid in Patients with Diabetic Ketoacidosis

In patients with diabetic ketoacidosis (DKA), the use of saline may be associated with longer time to DKA resolution, higher post-resuscitation serum chloride levels, lower post-resuscitation serum bicarbonate levels, and... read more

Effect of Early Fluvoxamine Treatment Among COVID-19 Patients

Effect of Early Fluvoxamine Treatment Among COVID-19 Patients

Treatment with fluvoxamine (100 mg twice daily for 10 days) among high-risk outpatients with early diagnosed COVID-19 reduced the need for hospitalisation defined as retention in a COVID-19 emergency setting or transfer to... read more

Early Remdesivir to Prevent Progression to Severe COVID-19 in Outpatients

Early Remdesivir to Prevent Progression to Severe COVID-19 in Outpatients

Among nonhospitalized patients who were at high risk for Covid-19 progression, a 3-day course of remdesivir had an acceptable safety profile and resulted in an 87% lower risk of hospitalization or death than placebo. A... read more

Chlorthalidone Improves Blood Pressure Control in Advanced Chronic Kidney Disease with Hypertension

Chlorthalidone Improves Blood Pressure Control in Advanced Chronic Kidney Disease with Hypertension

Among patients with advanced chronic kidney disease and poorly controlled hypertension, chlorthalidone therapy improved blood-pressure control at 12 weeks as compared with placebo. A total of 160 patients underwent randomization,... read more

Risk Factors for Severe COVID-19 Outcomes Among Adults Who Completed a Primary COVID-19 Vaccination

Risk Factors for Severe COVID-19 Outcomes Among Adults Who Completed a Primary COVID-19 Vaccination

In this analysis of data from 465 U.S. health care facilities, severe COVID-19 outcomes (i.e., respiratory failure, ICU admission, or death) were rare among adults aged ≥18 years after primary vaccination. These findings... read more

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 Pneumonia

The research will be retrospective, and will include a review of medical history of all patients admitted in the COVID-19 ICU of the University hospital Osijek during 2020 and 2021. Associated comorbidity, hospital admission... read more

Evaluating Vitamin C in Septic Shock

Evaluating Vitamin C in Septic Shock

Vitamin C monotherapy failed to significantly reduce mortality in septic shock patients as hypothesized. Our findings do not support its routine clinical use for this purpose. Of 124 subjects receiving study drug and included... read more

The Small Percutaneous Catheter vs. Large Open Chest Tube For Traumatic Hemothorax

The Small Percutaneous Catheter vs. Large Open Chest Tube For Traumatic Hemothorax

Small caliber 14-Fr PCs are equally as effective as 28- to 32-Fr chest tubes in their ability to drain traumatic HTX with no difference in complications. Patients reported better IPE scores with PCs over chest tubes,... read more

Hypocalcemia Association with In-hospital Mortality and Complications in Patients with Acute Pulmonary Embolism

Hypocalcemia Association with In-hospital Mortality and Complications in Patients with Acute Pulmonary Embolism

Pulmonary Embolism (PE) patients with hypocalcemia have higher in-hospital mortality than those without hypocalcemia. The in-hospital complications were also higher, along with longer length of stay. In the 2017 NIS, 187,989... read more

Energy Transmission in Mechanically Ventilated Children

Energy Transmission in Mechanically Ventilated Children

Mechanical energy (ME) better related to underlying lung pathology and patient outcome than MP. The delivery of generated energy to the lung was not dependent on endotracheal tube diameter (ETT) size during PC ventilation.... read more

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths worldwide and countless more admissions to hospitals and ICUs. Since... read more

Association of Volume Status During VV ECMO with Outcome

Association of Volume Status During VV ECMO with Outcome

Fluid overload in acute respiratory distress syndrome is associated with increased mortality. The purpose of this study was to investigate the association of cumulative fluid balance (CFB) during the first 7 days of eno-venous... read more