Tag: study
The Family in Preventing Delirium in the ICU
Extended visits, development of family-mediated activities, and redirection are non-pharmacological strategies that reduce the incidence of delirium in the ICU and offer multiple benefits to the patient and family/caregiver. The... read more
Casemix, management, and mortality of patients receiving emergency neurosurgery for TBI
Patients receiving emergency neurosurgery for traumatic brain injury (TBI) differed considerably in their admission characteristics and management across human development settings. Level of human development was associated... read more
Comparative analysis of the risks of hospitalisation and death associated with COVID-19 variants in England
The risk of severe outcomes following SARS-CoV-2 infection is substantially lower for omicron than for delta, with higher reductions for more severe endpoints and significant variation with age. Underlying the observed risks... read more
Association Between Dexamethasone Treatment for COVID-19 Patients and Rates of Hospital Readmission and Mortality
Current guidelines recommend use of dexamethasone, 6 mg/d, up to 10 days or until discharge for patients hospitalized with COVID-19. Whether patients who received less than 10 days of corticosteroids during hospitalization... read more
Electronic Pneumonia Decision Support Helps Reduce Mortality by 38% in Community Hospitals
Pneumonia was the leading cause of death from infectious diseases in the United States, even before the COVID-19 pandemic, and continues to be a leading cause of death. In the study, researchers at Intermountain Healthcare... read more
Sotrovimab Effect Among High-risk COVID-19 Patients
Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more
Percussion Pacing – An Almost Forgotten Procedure for Hemodynamically Unstable Bradycardias?
More than 80 years after its first description by Eduard Schott, percussion (fist) pacing remains a little known procedure even though it represents an instantly available and easy to perform treatment for temporary emergency... read more
Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema
This study compared the effect of placebo versus the bradykinin B2 receptor antagonist icatibant on symptoms of ACE inhibitor–associated angioedema in a mixed race population of patients. The study does not support the... read more
Therapeutic Hyperthermia Associated with Improved Survival in Afebrile Critically Ill Patients with Sepsis
Participants randomized to external forced-air warming did not have a difference in HLA-DR expression or IFN-γ production. In this pilot study, however, 28-day mortality was lower in the intervention group. Future research... read more
Incidence of Delirium in ICU Inpatients After Cognitive Exercise Intervention
In this study, the relevant RCTs on cognitive exercise in ICU inpatients with delirium were screened for systematic evaluation and meta-analysis, aiming to explore the impact of cognitive exercises and routine nursing on... read more
Staff Experiences Relating to Early Mobilisation of Mechanically Ventilated Patients in Intensive Care
Early mobilisation of mechanically ventilated patients has been suggested to be effective in mitigating muscle weakness, yet it is not a common practice. Understanding staff experiences is crucial to gain insights into what... read more
Palliative Care Consultation and End-of-life Outcomes in Hospitalized COVID-19 Patients
Palliative care consultation was not associated with CPR performed at the end-of-life but was associated with increased incidence of comfort care being utilized. These results suggest that utilizing palliative care consultation... read more
The 1,3,5 Approach to Pediatric Cardiac Arrest
While pediatric cardiac arrests are thankfully rare, their shock waves can seem incalculable. Several studies have outlined the mental health toll that these events can have on everyone involved. There is an appreciable... read more
Lung Ultrasonography Beyond the Diagnosis of Pediatrics Pneumonia
Pneumonia is a prevalent disease with considerable morbidity and mortality among the pediatric population. Early diagnosis and swift commencement of the correct treatment are vital for a favorable clinical outcome. Along... read more
Anticoagulation in COVID-19 Patients
Clinical, laboratory, and autopsy findings support an association between COVID-19 and thromboembolic disease. Acute COVID-19 infection is characterized by mononuclear cell reactivity and pan-endothelialitis, contributing... read more
Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients
In patients with arterial hypotension norepinephrine increased end-systolic ventricular elastance and arterial elastance. The effects of norepinephrine on stroke volume depend on baseline ventriculo-arterial coupling. Although... read more
Processed Electroencephalography-guided General Anaesthesia to Reduce Postoperative Delirium
Our primary analysis demonstrated a highly sensitive result with a pooled analysis of trials in which the intervention group adhered to manufacturer's recommended guidelines showing reduced incidence of postoperative delirium... read more
90% of ECMO-eligible COVID-19 Patients Died Amid Rationing
Nearly 90% of adult COVID-19 patients who were eligible for—but didn't receive—extracorporeal membrane oxygenation (ECMO) during the height of the pandemic died in the hospital owing to a lack of resources, even though... read more
Patients’ Perspectives on Point-of-Care Diagnostics in Acute COPD Exacerbations
Patients' perspectives showed that point-of-care diagnostics and treatment of acute COPD in exacerbation was considered a qualitative offer by the patients and their relatives. At the same time, it was crucial that the emergency... read more
Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients
COVID-19 considerably impacted swallowing function in the current study. Although many patients recovered within an acceptable timeframe, some experienced persistent severe dysphagia and a protracted recovery with dependence... read more
Cancer Treatments Not Associated with Inferior COVID-19 Outcomes
The findings of this study of patients with active cancer suggest that recent systemic anticancer treatments (SACTs) is not associated with inferior outcomes from COVID-19 infection. This has relevance for the care of... read more
Arterial pH with Hemodynamic Response Association to Vasopressin in Patients with Septic Shock
Compared with higher arterial pH, patients with septic shock and low arterial pH had lower odds of vasopressin response and higher catecholamine doses after vasopressin initiation. Similar to other vasopressors, the clinical... read more
