Tag: study
A Retrospective Cohort Study of 12,306 Pediatric COVID-19 Patients in the United States
Children and adolescents account for ~ 13% of total COVID-19 cases in the United States. However, little is known about the nature of the illness in children. The reopening of schools underlines the importance of understanding... read more
Sepsis Subclasses: A Framework for Development and Interpretation
Sepsis is defined as a dysregulated host response to infection that leads to life-threatening acute organ dysfunction. It afflicts approximately 50 million people worldwide annually and is often deadly, even when evidence-based... read more
Early Outcomes After Lung Transplantation for Severe COVID-19
The findings from our report show that lung transplantation is the only option for survival in some patients with severe, unresolving COVID-19-associated ARDS, and that the procedure can be done successfully, with good early... read more
Combined Platelet and Erythrocyte Salvage: Evaluation of a New Filtration-based Autotransfusion Device
This study demonstrated the performance of the SAME device. Platelets and red blood cells were salvaged without significant impact on cell integrity and function. In the meantime, leukocytes were not activated, and the washing... read more
Defining Major Trauma: a Delphi Study
Based upon the output of this Delphi study, major trauma may be defined as: "Significant injury or injuries that have potential to be life-threatening or life-changing sustained from either high energy mechanisms or low energy... read more
Safety of Arterial Catheterization Using the Distal Radial Approach in ICU Management
Distal radial approach (DRA) may be a safe option for insertion of a new A-line in the ICU. The study included 20 patients with a median age of 70 (interquartile range (IQR): 58.5–77) years: 10 patients with traumas,... read more
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells
Prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and recurrence of PCR-positive tests have been widely reported in patients after recovery from COVID-19, but some of these patients do... read more
Low Technology, Mild Controlled Hypothermia for Necrotizing Enterocolitis Treatment
Low technology, mild controlled hypothermia was feasible, not related to adverse effects, and effective treatment for NEC Modified Bell's Stage II/III. It avoided surgery, bowel perforation, and extensive intestinal resection;... read more
Asymptomatic and Symptomatic SARS-CoV-2 Infections After BNT162b2 Vaccination
This study found an association between vaccination with BNT162b2 in hospital employees and a decreased risk of symptomatic and asymptomatic infections with SARS-CoV-2. Limitations include the observational design; short... read more
Oral Midodrine Feasibility in Early Sepsis
This study proved the feasibility of clinical trial to use oral midodrine in early sepsis. The study was not powered to detect statistically significant differences between the two groups, and therefore, the results from... read more
The Clinical Utility of MRSA Nasal Screening to Rule Out MRSA Pneumonia
Nares screening for methicillin-resistant Staphylococcus aureus (MRSA) had a high specificity and NPV for ruling out MRSA pneumonia, particularly in cases of CAP/HCAP. Based on the NPV, MRSA nares screening is a valuable... read more
COVID-19: Dual Oxygen Concentrator System for Mechanical Ventilation
Sabah in Malaysian Borneo is among the Malaysian states which reported a high number of detected COVID-19 cases during the current pandemic. Due to geographical challenges and limited resources, clinicians developed novel... read more
Increasing the Reproducibility of Research Reduces the Problem of Apophenia
Apophenia, or the tendency of identifying meaningful patterns where none truly exist, is part of the human condition. We cannot surmount it, but we can strive to manage its influence. In the research context, apophenia can... read more
COVID-19: Convalescent Plasma vs. Standard Plasma
Administration of convalescent plasma to hospitalized patients with coronavirus disease 2019 infection increased antibodies to severe acute respiratory syndrome coronavirus disease 2 but was not associated with improved outcome. Enrollment... read more
