Tag: study
Impact of a Multifaceted Prevention Program on VAP Including Selective Oropharyngeal Decontamination
Ventilator-associated pneumonia (VAP) remains a serious complication of mechanical ventilation (MV), and has an incidence between 2 and 16 episodes per 1000 ventilator-days, an attributable mortality of 5–13%, excess ICU... read more
Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus
Patients with refractory status epilepticus (RSE) treated with continuous intravenous anesthetic drugs (cIVADs) may benefit from early initiation of such therapy. When cIVADs are applied in RSE, prescribing them early... read more
Short-term vs. Conventional Glucocorticoid Therapy in Acute Exacerbations of COPD
In patients presenting to the emergency department with acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD), 5-day treatment with systemic glucocorticoids was noninferior to 14-day treatment with regard to... read more
First Portable MRI Scanner for Neuro ICU
Health technology incubator Hyperfine Research and the Yale School of Medicine are testing out a first-of-its-kind, portable MRI scanner in the neuro intensive care unit (ICU). The point-of-care system, designed by Hyperfine,... read more
Effect of Organisational Factors on the Variation in Incidence of Delirium in ICU Patients
The mean incidence of delirium in the ICU was 29%. The organisational factors found including methods of delirium assessment, screening frequency, and hospital type were not related to the reported ICU delirium incidence. A... read more
POCUS Is Not a Magic Bullet
A man in his 50s checked into our ED recently feeling weak, nauseated, and short of breath for two days. He had no significant medical history, and had previously been active and healthy. A fingerstick glucose at triage... read more
Racial and Ethnic Differences in 30-Day Hospital Readmissions Among US Adults with Diabetes
In this study, black patients with diabetes had a significantly higher risk of readmission than members of other racial/ethnic groups. This increased risk was most pronounced among lower-income patients hospitalized in... read more
Healthcare Provider Perceptions of Cardiopulmonary Resuscitation Quality During Simulation Training
Cardiopulmonary resuscitation performance during mock codes does not meet the American Heart Association's quality recommendations. Healthcare providers have poor insight into the quality of cardiopulmonary resuscitation... read more
Norepinephrine Shortage and Mortality Among Patients With Septic Shock
Drug shortages in the United States are common, but their effect on patient care and outcomes has rarely been reported. This cohort study evaluated whether a national shortage of norepinephrine in the United States in 2011... read more
Echocardiographic Assessment of Pulmonary Artery Occlusion Pressure in Ventilated Patients
TEE accurately predicts invasive PAOP ≤ 18 mmHg in ventilated patients. This further increases its diagnostic value in patients with suspected acute lung injury/acute respiratory distress syndrome. During two consecutive... read more
Renal Outcomes of Vasopressin and Its Analogs in Distributive Shock
In patients with distributive shock, vasopressin and its analogs use is associated with a reduced need for renal replacement therapy and lower acute kidney injury (AKI) incidence. These results are supported by high risk... read more
Antipsychotic Drugs are Not Useful to Reduce Symptoms of Delirium
In patients receiving palliative care, individualized management of delirium precipitants and supportive strategies result in lower scores and shorter duration of target distressing delirium symptoms than when risperidone... read more
Interventions for Preventing Critical Illness Polyneuropathy and Critical Illness Myopathy
There is moderate quality evidence from two large trials that intensive insulin therapy reduces CIP/CIM, and high quality evidence that it reduces duration of mechanical ventilation, ICU stay and 180-day mortality, at the... read more
Epidemiology of Clinically Relevant Bleeding in Critically Ill Adolescents
Clinically Relevant Bleeding (CRB) is common in critically ill adolescents who are at high risk of venous thromboembolism (VTE). Admission after trauma or surgery can be used to stratify the risk of CRB in this population.... read more
Blood Grouping Identifies Patients at Risk for Developing Venous Thromboembolism
Based on study of more than 28,000 TJA patients, presurgical ABO blood group testing looks like an inexpensive way to identify patents at increased risk for symptomatic postoperative VTE. Prophylaxis regimens can dramatically... read more
Prehabilitation and Nutritional Support to Improve Perioperative Outcomes
Studies evaluating exercise and nutrition interventions before elective major surgery in adults are producing encouraging early results, but definitive clinical evidence is currently very limited. Future research should... read more
Palliative Care in the Emergency Department As Seen By Providers and Users
This study provides insights into targets for changes in Italian Emergency Departments. Room for improvement relates to training for healthcare professionals on palliative care, the development of a shared care pathway for... read more
Early Enteral Nutrition Associated with Improved Clinical Outcomes in Critically Ill Children
In critically ill children with hyperglycemia requiring inotropic support and/or mechanical ventilation, early enteral nutrition was independently associated with better clinical outcomes. Of 608 eligible subjects, 331... read more
