Tag: trauma
Rapid detection of clinically-relevant plasma direct oral anticoagulant levels following acute traumatic injury
In urgent clinical situations, such as trauma, urgent surgery or before thrombolysis, rapid quantification of direct oral anticoagulant plasma drug levels is warranted. Using the ClotPro® analyser, we assessed two novel... read more
Apnoeic Oxygenation for Emergency Anaesthesia of Pre-hospital Trauma Patients
Apnoeic oxygenation did not influence peri-intubation oxygen saturations, but it did reduce the frequency and duration of hypoxia in the post-intubation period. Given that apnoeic oxygenation is a simple low-cost intervention... read more
Trauma ICU Rounds – The rEVOLUTION of ECMO
What are the indications for ECMO beyond ARDS and refractory cardiogenic shock? In which patients should we consider eCPR and is this the new standard of care for patients sustaining out-of-hospital cardiac arrest? Finally,... read more
Epidemiology of Functional Seizures Among Adults Treated at a University Hospital
This case-control study found evidence to support previously reported associations, discovered new associations between functional seizures and PTSD, anxiety, and depression. An association between cerebrovascular disease... read more
Severe Trauma and Sepsis: Organ Damage and Tissue Repair
This book discusses recent progress in organ damage and tissue repair following severe trauma and sepsis. In part 1, it introduces the theory and clinical practice in organ damage. In part 2, it covers all the subjects... read more
Family satisfaction in a neuro trauma ICU
The purpose of this quality improvement initiative was to evaluate satisfaction of family members of patients in a neuro trauma ICU (NTICU). Adult patients (age 18+) admitted to the NTICU for at least 24 hours between... read more
Endotracheal intubation to reduce aspiration events in acutely comatose patients
Whether intubation results in a reduction in the incidence of aspiration events and whether these are more frequent in patients with low GCS scores are not yet established. The paucity of evidence on this topic makes clinical... read more
Viscoelastic Hemostatic Assay Augmented Protocols for Major Trauma Hemorrhage
Our international randomized trial has evaluated the role of VHAs to individualize care and augment empiric hemostatic resuscitation in the challenging and time-critical environment of trauma care. Empiric haemostatic therapy... read more
TEG for Hypocoagulable Patients with Non-Traumatic Bleeding
Thromboelastogram (TEG) has been extensively studied in trauma and surgical patients, but has not been well studied in nontraumatic bleeding, nor has its use been well evaluated in the emergency department. This study... read more
Limiting Radiation in Trauma Imaging & Trauma Resuscitation
Appropriate clinical decision-making in the initial evaluation and management of trauma patients in the emergency department is critical to optimize patient outcomes. This supplement provides evidence-based recommendations... read more
Turn the Lights On!: A Physician’s Personal Journey from the Darkness of Traumatic Brain Injury (TBI) to Hope, Healing, and Recovery
Often misdiagnosed and misunderstood, traumatic brain injury (TBI) may be a life-altering event which can produce a wide range of symptoms affecting physical as well as psychological health. Indeed, all senses can be affected,... read more
Quetiapine Decreases Mortality and Improve Neurological Outcomes in Critically-ill TBI Patients
Quetiapine may decrease mortality and improve neurological outcomes in critically-ill traumatic brain injury (TBI) patients. It has a dose-dependent effect to decrease intracranial pressure (ICP) and increase cerebral perfusion... read more
Computer Tomographic Assessment of Gastric Volume in Major Trauma Patients
In major trauma patients, overall stomach volume deriving from food, fluids and air must be expected to be around 400–500 mL. Gastric dilation caused by air is common but not typically associated with pre-hospital airway... read more
Intracerebral Hemorrhage (ICH)
For most patients, the best treatment seems to be high-quality supportive care. Aggressive interventions (e.g., causing dramatic drops in blood pressure and "prophylactic" hypertonic saline) may cause more harm than good. Cerebellar... read more
