Trend and Pattern of 100 ARDS Patients Teferred for VV ECMO Treatment

Referral to specialized center for venovenous (VV) ECMO treatment should be considered expeditiously in case of refractory ARDS, which is often lethal. Transport of unstable patients, although challenging, is feasible and... read more

Trend and Pattern of 100 ARDS Patients Teferred for VV ECMO Treatment

Mythbusting: (Empty IVC + Hyperkinetic Heart) Does Not Equal Volume Depletion

An empty IVC and hyperkinetic heart does not equal volume depletion. This combination of echocardiographic findings may result from either vasodilatory shock (as illustrated above) or hypovolemic shock. If encountered in... read more

Mythbusting: (Empty IVC + Hyperkinetic Heart) Does Not Equal Volume Depletion

Remestemcel-L reduces ARDS mortality in those under 65 years old

New data shows patients with COVID-19-related Acute Respiratory Distress Syndrome (ARDS) were up to 75 percent less likely to die when treated with remestemcel-L and dexamethasone. The data shows remestemcel-L reduced... read more

Remestemcel-L reduces ARDS mortality in those under 65 years old

POCUS of the Heart and Lungs in Patients with Respiratory Failure

Point-of-care ultrasound (POCUS) is a focus oriented tool for differentiating among cardiopulmonary diseases. Its value in the hands of emergency physicians, with various ultrasound experience, remains uncertain. We tested... read more

POCUS of the Heart and Lungs in Patients with Respiratory Failure

Decreased Mortality in ARDS Patients Treated with Corticosteroids

The use of glucocorticoids might result in reduced mortality in patients with ARDS. Glucocorticoids might be recommended as an adjunct to standard care for ARDS; however, the optimal dose and duration of steroid therapy remains... read more

Decreased Mortality in ARDS Patients Treated with Corticosteroids

Cytokine Adsorption Effect on Survival and Circulatory Stabilization in Patients Receiving ECPR

Even after the introduction of extracorporeal cardiopulmonary resuscitation (ECPR), survival after cardiac arrest remains poor. Excess release of vasoactive cytokines may be a reason for cardiovascular instability and death... read more

Cytokine Adsorption Effect on Survival and Circulatory Stabilization in Patients Receiving ECPR

Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins

A new Phase 3 trial to test the safety and efficacy of therapeutics for COVID-19 has begun enrolling patients hospitalized with life-threatening cases of COVID-19, including those with acute respiratory failure. The trial... read more

Clinical Trial of Therapeutics for Severely Ill Hospitalized COVID-19 Patients Begins

Validation of Sputum Gram Stain for Treatment of CAP and HCAP

The usefulness of sputum Gram stain in patients with community-acquired pneumonia (CAP) is controversial. There has been no study to evaluate the diagnostic value of this method in patients with healthcare-associated pneumonia... read more

Validation of Sputum Gram Stain for Treatment of CAP and HCAP

Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid

Combinations of coagulation factor concentrates suspended in albumin solutions can restore thromboelastometry parameters in the absence of plasma. This kind of artificial colloid fluids with coagulation-restoring characteristics... read more

Normalization of blood clotting characteristics using prothrombin complex concentrate, fibrinogen and FXIII in an albumin based fluid

Patient’s Clinical Presentation and CPPopt Availability: Any Association?

In this retrospective multicenter study, none of the selected admission and treatment variables were related to the CPPopt yield. The median CPPopt yield was 80.7% (interquartile range 70.9–87.4%). None of the selected... read more

Patient’s Clinical Presentation and CPPopt Availability: Any Association?

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate... read more

Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19 Patients

Peripheral Arteriovenous Malformations: Classification and Endovascular Treatment

In this review we cover the classification and endovascular management of arteriovenous malformations (AVMs). We begin by viewing AVMs in relation to the broader class of congenital vascular malformations and subsequently... read more

Peripheral Arteriovenous Malformations: Classification and Endovascular Treatment

Operative Techniques and Recent Advances in Acute Care and Emergency Surgery

The aim of this book is to identify and shed new light on the main surgical practices involved in acute care and trauma surgery. Adopting an evidence-based approach, a multidisciplinary team of surgeons and intensivists... read more

Operative Techniques and Recent Advances in Acute Care and Emergency Surgery

Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments

In this study, a quality improvement intervention that trained physicians to communicate and plan ICU care with family members of critically ill patients in the ICU using TLTs was associated with improved quality of family... read more

Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments

Mayo Clinic Critical and Neurocritical Care Board Review

Mayo Clinic Critical and Neurocritical Care Board Review is an all-inclusive review of the pathophysiology and care of the neurocritically ill and critically ill patient. The book reviews the core major critical care... read more

Mayo Clinic Critical and Neurocritical Care Board Review

Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock

PAC usage in cardiogenic shock (CS) is being revitalized by recent positive analyses of large registry and administrative databases. To realize the full potential of pulmonary artery catheters (PAC), more research is urgently... read more

Hemodynamic Profiling utility using Pulmonary Artery Catheters in Cardiogenic Shock

Isavuconazole vs. Voriconazole for Antifungal Prophylaxis in Lung Transplant Recipients

Isavuconazole was effective and well tolerated as antifungal prophylaxis following lung transplantation. A single-center, retrospective study of patients who received isavuconazole (September 2015–February 2018) or voriconazole... read more

Isavuconazole vs. Voriconazole for Antifungal Prophylaxis in Lung Transplant Recipients