Lung Histopathology in COVID-19 as Compared to SARS and H1N1 Influenza
Diffuse alveolar damage (DAD) was reported in 88% of patients with COVID-19. This is similar to both H1N1 (90%) and SARS (98%). Pulmonary microthrombi was reported in 57% of patients with COVID-19. This was similar to... read more
Panel Provides a Look at the Fast-changing Science of COVID-19 Diagnosis, Therapy, and Prevention
As the pace of research related to COVID-19 continues at an unprecedented rate, clinicians on the front line of the pandemic are challenged to keep up with a deluge of information to ensure they are bringing best practices... read more
Implantation of Impella CP Left Ventricular Assist Device Under the Guidance of 3D Intracardiac Echocardiography
Three-dimensional intracardiac echocardiography is a feasible option to guide implantation of the Impella CP for left ventricular mechanical support and should be carefully considered in cases where other imaging modalities... read more
Cancer Biomarker Measurement using a Smartphone
Canadian researchers create technology that reads cancer biomarker like a blood-sugar monitor. Researchers at the Canadian McMaster and Brock universities have created the prototype for a smartphone device to measure a biomarker... read more
Some Signs of Recovery From Severe COVID-19 Lung Damage
In two early studies, researchers said some patients showed signs of healing just weeks after leaving the hospital. Lingering shortness of breath and diminished stamina have dogged many COVID patients whose lungs were... read more
Outcomes of Patients Requiring Prolonged Acute vs. Short-Term Mechanical Ventilation
Over one-third of all hospitalized patients on mechanical ventilation require it for greater than or equal to 4 days. Prolonged acute mechanical ventilation patients exhibit a higher burden of both chronic and acute illness... read more
Dr. Fauci Headlines COVID-19-focused Opening Session at CHEST 2020
The COVID-19 pandemic upended the practices and lives of CHEST members—and changed CHEST 2020 into a virtual meeting—so it's fitting that this year's Opening Session focused on the defining global event of the year. Anthony... read more
Conservative or Liberal Oxygen Therapy in Adults After Cardiac Arrest
Conservative oxygen therapy was associated with a statistically significant reduction in mortality at last follow-up compared to liberal oxygen therapy but the certainty of available evidence was low or very low due to bias,... read more
All Intensivists Are Not Created Equal
I’d like to preface this story by saying that the majority of the intensivists I have worked with have been exceptional, caring, and professional. We had all established a good camaraderie, and we had mutual respect for... read more
Cardiothoracic Critical Care
This new bedside manual guides you through all the practical aspects of managing patients following cardiothoracic surgery and critically ill cardiology patients. Primarily designed to use in cardiothoracic intensive care... read more
Ultrasound Teleguidance to Reduce Healthcare Worker Exposure to COVID-19
The recent expansion of telemedicine during the coronavirus disease 2019 (COVID-19) pandemic is likely to continue based on the Food and Drug Administration's new guidelines supporting remote monitoring technologies as a... read more
Practical Guidance for Evidence-Based ICU Family Conferences
Because most critically ill patients lack decision-making capacity, physicians often ask family members to act as surrogates for the patient in discussions about the goals of care. Therefore, clinician-family communication... read more
Detecting Patient Deterioration Using Artificial Intelligence in a Rapid Response System
The developed artificial intelligence based on deep-learning, deep learning-based early warning system, accurately predicted deterioration of patients in a general ward and outperformed conventional methods. This study... read more
Data Visualization of Recent Sepsis Studies
Medicare is the US federal health insurance program for people who are 65 or older, certain younger people with disabilities, and people with End-Stage Renal Disease. Medicare spending in 2018 was 21% of the national US total... read more
Clinical and Pathophysiologic Aspects of ECMO-associated Hemorrhagic Complications
Extracorporeal membrane oxygenation (ECMO) is increasingly used to treat severe cases of acute respiratory or cardiac failure. Hemorrhagic complications represent one of the most common complications during ECMO, and can... read more
Balancing Intervention and Inaction During the COVID-19 Pandemic
More than 38 million people worldwide have been infected with the severe acute respiratory syndrome (SARS) coronavirus 2, creating intense pressure on clinicians to offer state-of-the-art, life-saving treatment to patients. The... read more
Synthesis and Systematic Review of Reported Neonatal COVID-19 Infections
A number of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections have been reported in neonates. Here, we aim to clarify the transmission route, clinical features and outcomes of these infections. We present... read more
High Plasma Levels Linked to Severe ARDS in Children with Respiratory Failure
Elevated surfactant protein D levels are associated with severe acute respiratory distress syndrome and poor outcomes in children with acute respiratory failure, according to results published in Chest. Elevated surfactant... read more
Viscoelastic Hemostatic Assay Augmented Protocols for Major Trauma Hemorrhage
Our international randomized trial has evaluated the role of VHAs to individualize care and augment empiric hemostatic resuscitation in the challenging and time-critical environment of trauma care. Empiric haemostatic therapy... read more
Brain Injury Is More Common in vv-ECMO Than VA-ECMO
Brain injury was more common in venoarterial extracorporeal membrane oxygenation (VA-ECMO) compared with venovenous extracorporeal membrane oxygenation (vv-ECMO). While ischemic brain injury was more common in venoarterial... read more
The Effectiveness of 8 Nonpharmaceutical Interventions Against COVID-19 in 41 Countries
Governments are attempting to control the COVID-19 pandemic with nonpharmaceutical interventions (NPIs). However, it is still largely unknown how effective different NPIs are at reducing transmission. Data-driven studies... read more
Outcomes of Neonates Born to Mothers With Severe COVID-19
In this cohort study, no evidence of vertical transmission of SARS-CoV-2 was identified in the first 101 newborns born to mothers positive for or with suspected SARS-CoV-2 infections at a large medical center in an epicenter... read more
