Thrombosis and Bleeding in ECMO without Anticoagulation
Extracorporeal membrane oxygenation (ECMO) causes both thrombosis and bleeding. Major society guidelines recommend continuous, systemic anticoagulation to prevent thrombosis of the ECMO circuit, though this may be undesirable... read more
TEG for Hypocoagulable Patients with Non-Traumatic Bleeding
Thromboelastogram (TEG) has been extensively studied in trauma and surgical patients, but has not been well studied in nontraumatic bleeding, nor has its use been well evaluated in the emergency department. This study... read more
Clinical Communication with Families in the Age of COVID-19
The admission of a critically ill patient to an intensive care unit (ICU) is a distressing event for the patient, their family and friends, which has been amplified by the impact of the covid-19 pandemic. Many hospitals... read more
Effect of Early Activity Combined with Early Nutrition on Acquired Weakness in ICU Patients
This trial has the potential to identify a novel strategy for preventing or managing ICU-AW. The findings may increase the clinical knowledge about nutrition and mobilization interventions for people with ICU-AW, and contribute... read more
Monitoring of the Adult Patient on VA ECMO
Venoarterial extracorporeal membrane oxygenation (VA ECMO), a form of mechanical circulatory support, had its origins in the operating room as cardiopulmonary bypass and has evolved for use in the intensive care unit and... read more
Efficacy and Safety of a Paired Sedation and Ventilator Weaning
The purpose of this study is to determine the impact of a new RN/RRT (Registered Nurse/Registered Respiratory Therapist) directed 2-step protocol to wean patients off of a ventilator. This protocol involves daily attempts... read more
Endothelial Dysfunction Role During COVID-19
Emerging data suggest a crucial role of endothelial dysfunction during SARS-CoV-2 infection, as a direct target of the virus and inflammatory cytokines as well as the main actor in orchestrating a pro-inflammatory and pro-coagulant... read more
Stress Hyperglycemia and Mortality in Subjects With Diabetes and Sepsis
Stress-induced hyperglycemia is a relevant prognostic factor also in the presence of diabetes. Mild-to-moderate stress hyperglycemia is considered a protective reaction to providing fuel for the immune system and brain at... read more
FDA Authorized First Point-of-Care Antibody Test for COVID-19
U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first serology (antibody) point-of-care (POC) test for COVID-19. The Assure COVID-19 IgG/IgM Rapid Test Device was first authorized for... read more
Gastrointestinal Complications in Critically Ill Patients With and Without COVID-19
This study found a higher rate of gastrointestinal complications, including mesenteric ischemia, in critically ill patients with COVID-19 compared with propensity score–matched patients without COVID-19, suggesting a distinct... read more
Early Arterial Embolization and Mortality in Mechanically Ventilated Patients With Hemoptysis
The objective of this study was to clarify whether early intervention by arterial embolization reduced mortality in mechanically ventilated patients with hemoptysis. The results show that early intervention by arterial... read more
Pre-hospital Care & Interfacility Transport of 385 COVID-19 Emergency Patients
All participating air ambulance providers were prepared for COVID-19. Safe care and transport of suspected or confirmed COVID-19 patients is achievable. Most patients on primary missions were transported by ground. These... read more
Mortality Outcomes with Hydroxychloroquine and Chloroquine in COVID-19
No benefit of hydroxychloroquine or chloroquine on the survival of COVID-19 patients found. For hydroxychloroquine, the confidence interval is compatible with increased mortality or negligibly reduced mortality. Findings... read more
Risk of Death More Than Doubled in People with Both Flu and COVID-19
People infected with both flu and SARS-CoV-2 are more than twice as likely to die as someone with the new coronavirus alone, emerging evidence from England has shown. An analysis by Public Health England (PHE) of cases... read more
Measuring COVID-19 Fatalities Among EMS Providers
The devastating effects of the COVID-19 pandemic resonate around the world. Escalating infection and death rates are reported daily. While emergency medical services clinicians have been operating at the far forward front... read more
Core Curriculum for Pain Management Nursing
Learn how to successfully work with patients in pain with The Core Curriculum for Pain Management Nursing, 3rd Edition. Written by the American Society for Pain Management Nursing (the primary nursing organization in pain... read more
Fibrin-derived Peptide as Salvage Treatment in Critically Ill Patients with COVID-19-associated ARDS
After SARS-CoV-2 first occurred in China in December of 2019, it set out to become a global pandemic. Critically ill patients constitute about 2–9% of all infected patients and progress from pneumonia and hypoxemia to multi-organ... read more
Standardized Perioperative Feeding Protocol Improves Outcomes
An aggressive, but safe, perioperative feeding protocol implemented in a homogenous low-risk neonatal cardiac surgical population improves feeding outcomes, including increased weight gain, as well as decreased postoperative... read more
COVID-19: Practical Strategies to Reduce Nosocomial Transmission
The frontline healthcare workers (HCWs) are at risk for contracting the COVID-19 disease when caring for patients and providing aerosol-generating procedures. Until further high-quality studies generate robust evidence, defining... read more
Essentials of Perioperative Nursing
Essentials of Perioperative Nursing, Sixth Edition is an essential reference for new perioperative nurses as well as experienced nurses who need a refresher. Succinct and easy to use, it addresses the basics associated with... read more
Dual Therapy Using Sildenafil and Milrinone Superior to Monotherapy in Neonates with Severe PPHN
Dual therapy using sildenafil and milrinone was superior to monotherapy with either drug in neonates with severe persistent pulmonary hypertension (PPHN) and is recommended for use in resource-constrained settings. A double-blind... read more
Advances In ICU Care Are Saving More Patients Who Have COVID-19
One thing that has improved a lot over the course of the pandemic is treatment of seriously ill COVID-19 patients in intensive care units. Here's one man's success story. If you think all the coronavirus news is bad, consider... read more
