Best Practice Advisories Improve Sedation Protocol Compliance in the ICU

Best practice advisories can be effectively used in ICUs to improve sedation protocol compliance and may mitigate potential propofol-related hazardous conditions. Best practice advisories should undergo continuous quality... read more

Comprehensive Review of Infectious Diseases

Perfect for board review or quick reference in clinical practice, Comprehensive Review of Infectious Diseases is a balanced, high-yield resource covering the full range of infectious disease topics. Whether you're preparing... read more

Comprehensive Review of Infectious Diseases

Wuhan Coronavirus Infections Could Be 30 Times Higher Than Official Total

The number of people infected with a SARS-like form of coronavirus in Wuhan, China could already be more than 30 times higher the the official tally, researchers in Hong Kong have warned. Gabriel Leung, the chair of public... read more

Animal Viruses and Humans, a Narrow Divide: How Lethal Zoonotic Viruses Spill Over and Threaten Us

"To reproduce promiscuously and to wreak havoc wherever they can find a home," this is the sole raison d'être of viruses writes Dr. Warren Andiman, an HIV/AIDS researcher who has been on the front lines battling infectious... read more

Animal Viruses and Humans, a Narrow Divide: How Lethal Zoonotic Viruses Spill Over and Threaten Us

Association Between Hypothermia/Ischemia Ratio and Functional Outcome

Although a larger hypothermia/ischemia ratio was associated with good functional outcome after out-of-hospital cardiac arrest in this cohort, this association is primarily driven by duration of time to return of spontaneous... read more

Leading EHR System Adopts Bundle to Prevent ICU Delirium

Seminal studies at Vanderbilt University Medical Center over the past two decades by pulmonary and critical care specialist Wes Ely, M.D. and colleagues have spurred ICU delirium research, and the resulting body of evidence... read more

Clinical Features of Patients Infected with Coronavirus in Wuhan, China

A cohort of 41 patients with laboratory-confirmed 2019-nCoV infection. Patients had serious, sometimes fatal, pneumonia and were admitted to the designated hospital in Wuhan, China, by Jan 2, 2020. Clinical presentations... read more

Spillover: Animal Infections and the Next Human Pandemic

The next big human pandemic, the next disease cataclysm, perhaps on the scale of AIDS or the 1918 influenza, is likely to be caused by a new virus coming to humans from wildlife. Experts call such an event "spillover"... read more

Spillover: Animal Infections and the Next Human Pandemic

The New Coronavirus: What We Do And Don’t Know

A rapidly evolving health story broke in late December when a novel illness originating in Wuhan, China made the news. Reports of the number of infected people swiftly rose, and isolated cases of this new coronavirus —... read more

The Next Pandemic: On the Front Lines Against Humankind’s Gravest Dangers

In this riveting book, Khan tells the dramatic stories of these crises—as well as the stories we don't know—of congo-crimean hemorrhagic fever infecting abattoirs in the United Arab Emirates, as cigarette-smoking local... read more

The Next Pandemic: On the Front Lines Against Humankind’s Gravest Dangers

Temporal Utilization Trends in Prehospital Mechanical CPR Devices

Chest compressions have remained one of the most visible and effective components of prehospital resuscitation, dating back to the inception of modern emergency medical services (EMS). Although the idea and technique... read more

A Novel Coronavirus from Patients with Pneumonia in China

4 lower respiratory tract samples, including bronchoalveolar-lavage fluid, were collected from patients with pneumonia of unknown cause who were identified in Wuhan on December 21, 2019, or later and who had been present... read more

Frailty Predicts 30-day Mortality in Intensive Care Patients

Premorbid frailty was common in general ICU patients and was an independent predictor of death. Our study suggests that frailty could be a valuable addition in outcome prediction in intensive care. The receiver operating... read more

Effects of a Multimodal Program Including Simulation on Job Strain Among Nurses Working in ICUs

Among ICU nurses, an intervention that included education, role-play, and debriefing resulted in a lower prevalence of job strain at 6 months compared with nurses who did not undergo this program. Further research is... read more

Superbugs: The Race to Stop an Epidemic

A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician,... read more

Superbugs: The Race to Stop an Epidemic

Clinical Decision Support Systems: Future or Present in ICU?

Clinical decision support systems (CDSS) are today, a reality. More complex, useful systems will be developed in the near future, forging CDSS an essential part of ICU monitoring. However, we need to understand the algorithms... read more

Artificial Intelligence or Merely a Symptom of a Broken Healthcare System?

We are constantly hunting for newer and better sources of information. This leads to a perpetual generation of newer lab tests, different hemodynamic gizmos, and fresh decision tools. Some of these pan out. Most don't. Why... read more

A CT Scanner in Your Pocket? Lung Ultrasonography Beats Chest Radiography

Lung ultrasound is still a relatively young diagnostic modality, but it is evolving and growing at a rapid pace. Harrison's manual of internal medicine deemed to it to be a "useless" modality as recently as 2001. Once... read more

Neonatal Lung Ultrasonography

This book presents lung ultrasound as an accurate, reliable, low-cost and simple imaging technique, which poses no risk of radiation damage, making bedside use both feasible and convenient in neonatal wards. The aim of... read more

Neonatal Lung Ultrasonography

Depth of Anesthesia in Children Undergoing Cardiac Surgery Under Extracorporeal Circulation

In children undergoing cardiac surgery in our department, the use of sevoflurane-balanced anesthesia during cardiopulmonary bypass showed no superiority of inhalational agents over total intravenous anesthesia with opioids... read more

PPIs vs. Histamine-2 Receptor Blockers for ICU Stress Ulcer Prophylaxis

ICU patients assigned to proton-pump inhibitors (PPIs) versus histamine-2 receptor blockers (H2RBs) for ulcer prophylaxis had marginally higher 90-day mortality that just missed statistical significance. Significantly fewer... read more

When Exercise Comes to the Hospital’s ICUs

Even short hospital ICU stays can cause lasting problems for patients. Can early mobility and exercise help? Apna Kudchadkar still remembers the morning in 2010 that shaped the trajectory of her scientific research. She... read more