Conservative vs. Interventional Treatment for Spontaneous Pneumothorax
Although the primary outcome was not statistically robust to conservative assumptions about missing data, the trial provides modest evidence that conservative management of primary spontaneous pneumothorax was noninferior... read more
Human-to-Human Transmission of a Novel Coronavirus in Vietnam
This article describe transmission of Coronavirus from a father, who had flown with his wife from Wuhan to Hanoi, to his son. The findings suggest that the incubation period in the son may have been 3 days or less. On... read more
WHO Declares the New Coronavirus Outbreak a Public Health Emergency of International Concern
The International Health Regulations Emergency Committee believes that it is still possible to interrupt virus spread, provided that countries put in place strong measures to detect disease early, isolate and treat cases,... read more
Aldosterone Synthase in Peripheral Sensory Neurons Contributes to Mechanical Hypersensitivity during Local Inflammation in Rats
Local production of aldosterone by its processing enzyme aldosterone synthase within peripheral sensory neurons contributes to ongoing mechanical hypersensitivity during local inflammation via intrinsic activation of neuronal... read more
Neuroprognostication Practices in Postcardiac Arrest Patients
Neuroprognostic approaches to hypoxic-ischemic encephalopathy vary among physicians and are often not consistent with current guidelines. The overall inconsistency in approaches and deviation from evidence-based recommendations... read more
Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data
Systemic inflammatory response syndrome and Sequential Organ Failure Assessment initially identified distinct populations. Using systemic inflammatory response syndrome resulted in earlier electronic health record sepsis... read more
Blood Transfusion – Fresh vs. Standard-issue in Critically Ill Pediatric Patients
Among critically ill pediatric patients, the use of fresh red blood cells did not reduce the incidence of new or progressive multiple organ dysfunction syndrome (including mortality) compared with standard-issue red blood... read more
Best Practice Advisories Improve Sedation Protocol Compliance in the ICU
Best practice advisories can be effectively used in ICUs to improve sedation protocol compliance and may mitigate potential propofol-related hazardous conditions. Best practice advisories should undergo continuous quality... read more
Comprehensive Review of Infectious Diseases
Perfect for board review or quick reference in clinical practice, Comprehensive Review of Infectious Diseases is a balanced, high-yield resource covering the full range of infectious disease topics. Whether you're preparing... read more
Wuhan Coronavirus Infections Could Be 30 Times Higher Than Official Total
The number of people infected with a SARS-like form of coronavirus in Wuhan, China could already be more than 30 times higher the the official tally, researchers in Hong Kong have warned. Gabriel Leung, the chair of public... read more
Animal Viruses and Humans, a Narrow Divide: How Lethal Zoonotic Viruses Spill Over and Threaten Us
"To reproduce promiscuously and to wreak havoc wherever they can find a home," this is the sole raison d'être of viruses writes Dr. Warren Andiman, an HIV/AIDS researcher who has been on the front lines battling infectious... read more
Association Between Hypothermia/Ischemia Ratio and Functional Outcome
Although a larger hypothermia/ischemia ratio was associated with good functional outcome after out-of-hospital cardiac arrest in this cohort, this association is primarily driven by duration of time to return of spontaneous... read more
Leading EHR System Adopts Bundle to Prevent ICU Delirium
Seminal studies at Vanderbilt University Medical Center over the past two decades by pulmonary and critical care specialist Wes Ely, M.D. and colleagues have spurred ICU delirium research, and the resulting body of evidence... read more
Clinical Features of Patients Infected with Coronavirus in Wuhan, China
A cohort of 41 patients with laboratory-confirmed 2019-nCoV infection. Patients had serious, sometimes fatal, pneumonia and were admitted to the designated hospital in Wuhan, China, by Jan 2, 2020. Clinical presentations... read more
Spillover: Animal Infections and the Next Human Pandemic
The next big human pandemic, the next disease cataclysm, perhaps on the scale of AIDS or the 1918 influenza, is likely to be caused by a new virus coming to humans from wildlife. Experts call such an event "spillover"... read more
The New Coronavirus: What We Do And Don’t Know
A rapidly evolving health story broke in late December when a novel illness originating in Wuhan, China made the news. Reports of the number of infected people swiftly rose, and isolated cases of this new coronavirus —... read more
The Next Pandemic: On the Front Lines Against Humankind’s Gravest Dangers
In this riveting book, Khan tells the dramatic stories of these crises—as well as the stories we don't know—of congo-crimean hemorrhagic fever infecting abattoirs in the United Arab Emirates, as cigarette-smoking local... read more
Temporal Utilization Trends in Prehospital Mechanical CPR Devices
Chest compressions have remained one of the most visible and effective components of prehospital resuscitation, dating back to the inception of modern emergency medical services (EMS). Although the idea and technique... read more
A Novel Coronavirus from Patients with Pneumonia in China
4 lower respiratory tract samples, including bronchoalveolar-lavage fluid, were collected from patients with pneumonia of unknown cause who were identified in Wuhan on December 21, 2019, or later and who had been present... read more
Frailty Predicts 30-day Mortality in Intensive Care Patients
Premorbid frailty was common in general ICU patients and was an independent predictor of death. Our study suggests that frailty could be a valuable addition in outcome prediction in intensive care. The receiver operating... read more
Effects of a Multimodal Program Including Simulation on Job Strain Among Nurses Working in ICUs
Among ICU nurses, an intervention that included education, role-play, and debriefing resulted in a lower prevalence of job strain at 6 months compared with nurses who did not undergo this program. Further research is... read more
Superbugs: The Race to Stop an Epidemic
A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician,... read more
