Can Cooling Patients Help After a Cardiac Arrest?
The cooling trial, involving nine UK hospitals, is being led by researchers at the University Hospital of Wales, Cardiff. Altogether, 1,900 patients worldwide are part of the trial, called TTM2. Half of patients were... read more
Coronavirus Can Spread Between Humans
The leader of a Chinese government team of experts announced Monday that human-to-human transmission of a new coronavirus has been confirmed. The finding could raise fears that the infection might not require contact with... read more
Understanding the Essentials of Critical Care Nursing
Understanding the Essentials of Critical Care Nursing provides novice critical care nurses with a firm foundation so that they are able to understand the complexities of care; deliver safe, effective care; and begin their... read more
Hypertonic vs. Hypotonic, Osmolality, and Other Fun Nursing Concepts
The basic concepts underlying the body's mechanisms for keeping systems functioning are complex processes involving the ebb and flow of fluid and molecules controlled by several systems. It is a delicate balance and one... read more
Approaches to EOL Decision-making For Patients Affected by Sepsis and ARDS
A Qualitative Study of Patients With Acute Respiratory Distress Syndrome (ARDS) and Sepsis and Their Surrogates. The purpose of this study was to develop hypotheses of patient and surrogate's rationale for decision-making. Patients... read more
Risk Factors for the Development of ARDS in Mechanically Ventilated Adults in Peru
In this study of mechanically ventilated patients, 31% of study participants had acute respiratory distress syndrome (ARDS) at some point during their ICU stay. Optimal lung-protective ventilation was not used in a majority... read more
Clinical Practice Manual for Pulmonary and Critical Care Medicine
Clinical Practice Manual for Pulmonary and Critical Care Medicine, by Judd W. Landsberg, MD, is a unique point-of-care manual that provides essential information on managing inpatients and outpatients with common, serious... read more
Automated Anesthetic Management Outperforms Manual Control and May Have an Impact on Delayed Neurocognitive Recovery
Among older, non-frail patients undergoing moderate and high-risk noncardiac surgery, an automated anesthetic management using the combination of three independent closed-loop systems outperformed manual control and may have... read more
Clinical Prediction Models: A Practical Approach to Development, Validation, and Updating
Prediction models are important in various fields, including medicine, physics, meteorology, and finance. Prediction models will become more relevant in the medical field with the increase in knowledge on potential predictors... read more
Maternal Risk Modeling in Critical Care
Risk prediction models specific to the maternal critical care population was developed. The models compare favorably against general adult ICU risk prediction models in current use within this population. The aim was to... read more
Impact of Levosimendan on Weaning from Peripheral VA-ECMO in ICU
This study suggests that levosimendan might be associated with a beneficial effect on venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in ICU patients. The difference in mortality among propensity-matched... read more
Intravenous Fluid Therapy in Critically Ill Adults
Despite the administration of intravenous fluids to critically ill patients being a near-universal intervention, the available evidence base guiding their safe and appropriate use is scarce and derived mainly from academically... read more
Emergency Medicine: Diagnosis and Management
Emergency Medicine: Diagnosis and Management incorporates the latest ideas and evidence base underpinning best practice emergency medicine care. This book covers a wide variety of emergencies, including general medical, critical... read more
Activin Type II Receptor Blockade for Treatment of Muscle Depletion in COPD
Blocking the action of negative muscle regulators through the activin type II receptors with bimagrumab treatment safely increased skeletal muscle mass but did not improve functional capacity in patients with COPD and low... read more
Measuring Patient Mobility in the ICU Using a Novel Noninvasive Sensor
Noninvasive mobility sensor is a novel and feasible method for automating evaluation of ICU patient mobility. Three Microsoft Kinect sensors (Microsoft, Beijing, China) were deployed in one ICU room to collect continuous... read more
Prehospital On-scene Anesthetist Treating Severe TBI Patients is Associated with Lower Mortality and Better Neurological Outcome
Patients with isolated traumatic brain injury (TBI) are likely to benefit from effective prehospital care to prevent secondary brain injury. Only a few studies have focused on the impact of advanced interventions in TBI... read more
Impact of Paralytic Agent on Postintubation Sedation
The aim of this study was to evaluate the difference in the time to postintubation sedation between patients receiving etomidate and either succinylcholine or rocuronium in the prehospital setting. This study suggests... read more
Vitamin Treatment For Sepsis Fails In Large Trial
Hope for an effective and inexpensive treatment for the deadly condition sepsis has dimmed following results of a major new study. Researchers had hoped that a simple treatment involving infusions of vitamin C, vitamin... read more
Finding a New Way to Fight Late-stage Sepsis by Boosting Cells’ Antibacterial Properties
Researchers have developed a way to prop up a struggling immune system to enable its fight against sepsis, a deadly condition resulting from the body's extreme reaction to infection. The scientists used nanotechnology... read more
Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock
In patients with septic shock, treatment with intravenous vitamin C, hydrocortisone, and thiamine, compared with intravenous hydrocortisone alone, did not significantly improve the duration of time alive and free of vasopressor... read more
Effect of Stress Ulcer Prophylaxis on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation
Among ICU patients requiring mechanical ventilation, a strategy of stress ulcer prophylaxis with use of proton pump inhibitors vs histamine-2 receptor blockers resulted in hospital mortality rates of 18.3% vs 17.5%, respectively,... read more
Sepsis Kills Twice as Many People as Experts Feared
Sepsis, which is triggered by an infection, is the cause of 1 in 5 deaths worldwide. It is thought to have killed 47,860 in 2017 - ranking us 45th worst out of 195 countries. Researchers estimate the condition claimed... read more
