Cardiac Arrest Following Prone Positioning
The complications that can arise from the prone position are often underestimated. Proceduralists, surgeons, and anesthesiologists need to be thoroughly knowledgeable about the common physiological changes that can occur... read more
Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients
Among adults receiving mechanical ventilation in the ICU, adding early in-bed Cycling to usual physiotherapy did not improve physical function at 3 days after discharge from the ICU compared with Usual physiotherapy alone.... read more
Predictive Value of Multiple Scoring Systems in the Prognosis of Septic Patients with Different Infection Sites
The heterogeneity nature of sepsis is significantly impacted by the site of infection. This study aims to explore the predictive value of multiple scoring systems in assessing the prognosis of septic patients across different... read more
Early Ketamine Sedation Outcomes Among Mechanically Ventilated COVID-19 Patients
In a diverse sample of U.S. hospitals, about one in 30 patients mechanically ventilated with COVID-19 received ketamine infusions. Early ketamine may have an association with higher hospital mortality, increased total cost,... read more
Secretomic Approach Value for Distinguishing Patients with COVID-19 Viral Pneumonia Among ICU Patients with Respiratory Distress
In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with Nonviral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand... read more
Noninvasive Ventilation for Preoxygenation during Emergency Intubation
Among critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation resulted in a lower incidence of hypoxemia during intubation than preoxygenation with an oxygen mask. Among the 1,301... read more
Early vs. Delayed Enteral Nutrition in ICU Sepsis Patients
Early enteral nutrition may not affect mortality rates when analyzed using propensity score matching. However, our findings indicate that early enteral nutrition is associated with shorter ICU stays and a lower incidence... read more
Risk Factors of Post-intubation Hypotension in Severe Pneumonia Patients
Post-intubation hypotension (PIH) was one of the serious complications after Endotracheal intubation (ETI) in Severe pneumonia (SP) patients. The risk factors of PIH were investigated in SP patients to provide a theoretical... read more
A Critical Reappraisal of Vasopressin and Steroids in IHCA
In view of the presented discussion/evidence and until publication of new evidence from a large, ongoing Swedish RCT, we suggest that vasopressin-steroids-epinephrine (VSE) might be considered in in-hospital cardiac arrest... read more
Perioperative Hemodynamic Monitoring and Goal Directed Therapy: From Theory to Practice
This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside.... read more
Hydrocortisone, Ascorbic Acid, and Thiamine Combination Therapy Efficacy for the Management of Sepsis and Septic Shock
In this systematic review, we found that hydrocortisone, ascorbic acid, and thiamine (HAT) regimen may be useful for reducing the duration of vasopressor use and improve organ functions in patients with sepsis and septic... read more
Patients with TBI: Characteristics, Triage, Primary Referral and Mortality
Traumatic brain injury (TBI) is a potential high-risk condition, but appropriate care pathways, including prehospital triage and primary referral to a specialized neurosurgical centre, can improve neurological outcome and... read more
The role of pleural pressure and airway closure during mechanical ventilation
Related to our paper, Van Egmond et al. highlighted key physiological concepts we must be aware of. We believe, however, that the described physiological com-plexity has limited impact on the daily use of esophageal pressure... read more
Immunosuppression Not Associated with a Higher Incidence of ICU-acquired Bacterial Bloodstream Infections
In this monocentric, retrospective observational cohort study, the incidence of ICU-acquired bacterial BSI was not different between immunocompromised and non-immunocompromised patients. This suggests that the clinical... read more
Improving Outcomes in Nosocomial Pneumonia
Nosocomial pneumonia (NP) represents a leading nosocomial infection and results in substantial morbidity and cost. Over the last several years, the evidence has evolved which directs our approach to NP. Specifically, the... read more
Two weaning strategies for NIV in COPD patients with ARF
Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more
Incidence of AKI and attributive mortality in ARDS randomized trials
The development of acute kidney injury (AKI) after the acute respiratory distress syndrome (ARDS) reduces the chance of organ recovery and survival. The purpose of this study was to examine the AKI rate and attributable mortality... read more
Sepsis-induced coagulopathy: a matter of timeline
Leone et al. have nicely outlined the most frequent questions about thrombocytopenia in sepsis. Besides thrombocytopenia, sepsis indeed induces numerous pathophysiological changes. Among these, the acute-phase response... read more
Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol
This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more
Oxford Textbook of Advanced Critical Care Echocardiography
Advanced critical care echocardiography brings many benefits to critical care medicine. For those wishing to practice echo at a more advanced level, it is necessary to master the theoretical aspects. The Oxford Textbook... read more
Pneumocystis Jirovecii Pneumonia in Patients with and without Chronic Pulmonary Disease
Procalcitonin level, pneumothorax, neutrophil count at 14 days, and hemoglobin level at 14 days after admission were poor prognostic indicators among patients with NCPD-PJP. Neutrophil count was related with poor prognosis... read more
Proposal for a 4-Level Classification System of Severe COPD Exacerbation According to Healthcare Resource Utilization
The definition of an acute exacerbation of Chronic Obstructive Pulmonary Disease (COPD) has been modified several times the last decade in Global Initiative for COPD (GOLD) recommendations. According to the updated GOLD... read more
