The Hidden Value of MRI: Modifying Treatment Decisions in C-spine Injuries

This study provides a critical evaluation of the implications of additional magnetic resonance imaging (MRI) use in the diagnosis of c-spine injuries. We have demonstrated that an adjunctive MRI extends patients' ED stays,... read more

Neurocritical Care for the Advanced Practice Clinician

By utilizing a review of case-based studies and providing concise management recommendations from leaders in the field, this book provides essential knowledge for those practicing in a dynamic specialty. In the rapidly... read more

Neurocritical Care for the Advanced Practice Clinician

Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals

Empiric treatment for suspected community-onset sepsis accounts for about half of broad-spectrum antibiotic use in US hospitals even though resistant organisms are isolated in only 7% of patients with community-onset sepsis... read more

Complex Infusion Volumes Interaction and Confounding Factors with Lactate Clearance in Septic Shock

A recent article by Ahlstedt et al. published in Intensive Care Medicine examining the impact of restrictive fluid management on lactate clearance in septic shock patients within the intensive care unit (ICU) piqued our interest.... read more

Quick Reference to Critical Care

Sharpen your critical care skills, with the fully updated Quick Reference to Critical Care, fifth 5th edition. This well-illustrated pocket guide covers the full range of critical care scenarios, listing each disorder, medication,... read more

Quick Reference to Critical Care

Ketamine Can Be a Transformational Agent But Not Without Risk or Danger

Ketamine is growing as a tool in the world of emergency medicine, offering a broad spectrum of applications that underscore its pivotal role in modern therapeutic regimens. It is increasingly being recognized for its... read more

Sepsis Alert Systems, Mortality, and Adherence in Emergency Departments

This systematic review and meta-analysis demonstrated the significant association of implementing sepsis alert systems in the Emergency Departments (ED) with patient outcomes. These findings indicate that sepsis alert... read more

Navigating the Complexity of ECMO and Positioning in ARDS Treatment

We read with great interest the network meta-analysis by Sud et al. comparing venovenous extracorporeal membrane oxygenation (VV-ECMO), prone positioning, and supine mechanical ventilation in patients with severe hypoxemic... read more

Genetic Testing in Early-onset Atrial Fibrillation

Atrial fibrillation (AF) is a globally prevalent cardiac arrhythmia with significant genetic underpinnings, as highlighted by recent large-scale genetic studies. A prominent clinical and genetic overlap exists between... read more

EKG/ECG Interpretation Made Easy

In this guide, you will understand how ECGs are performed, what they represent about the heart, and what it means to see something you don't think is normal. Before you get into the hard stuff—the actual interpretation... read more

EKG/ECG Interpretation Made Easy

Trauma Medical Home: New Coordinated Care Model for Injured Older Adults

Older adults who suffer serious injuries from a fall or a motor vehicle accident often have impaired long-term functioning and diminished quality of life. A new study, published in JAMA Surgery by researcher-clinicians... read more

Treatment of Refractory Cardiac Arrest by Controlled Reperfusion of the Whole Body

This multicenter, prospective, all-comers observational study has provided preliminary data on a new approach to treat patients with prolonged refractory CA and CCPR by applying an advanced extracorporeal perfusion circuit,... read more

Antifungal Prophylaxis of COVID-19 Associated Pulmonary Aspergillosis in Ventilated Patients

This study investigated the impact of POSA prophylaxis on risk of CAPA development in mechanically ventilated COVID-19 patients receiving corticosteroids. We observed a significant variation in CAPA incidence rates among... read more

High-flow Nasal Cannula Oxygen vs. NIV in AHF-related ARF

In this pilot study, we did not observe a statistically significant difference in changes in respiratory rate among patients with acute respiratory failure (ARF) due to acute heart failure (AHF) and managed with high-flow... read more

Another Perspective on Tidal Volume: From Statistics to Uncertainty

We have read with great interest the recent editorial by Pellegrini et al. Undoubtedly, now more than ever, we have begun to question the true role of tidal volume (VT) in acute respiratory distress syndrome (ARDS). As... read more

Vasoconstriction in Septic Shock

Septic shock is associated with endothelial dysfunction leading to arterial and venous dilation, alterations in regional blood flow distribution, and microcirculatory disturbances. Fluids and vasopressors are the key... read more

Secretomic Approach Value in COVID-19 Viral Pneumonia Among Patients With Respiratory Distress

this article presents an innovative and promising secretomic analysis to distinguish VPP patients from NV-ICU patients using combinations of protein markers. Among the identified proteins, ficolin-3 and proteoglycan-4 appear... read more

Prevalence and Survival of Prolonged VV ECMO for ARDS

The understanding of prolonged venovenous extracorporeal membrane oxygenation (VV ECMO) in the setting of acute respiratory distress syndrome (ARDS) is evolving and durations of support once considered extreme are now commonplace.... read more

PEEP May Cause Harm in Less Severe ARDS

A higher positive end-expiratory pressure (PEEP) strategy may cause harm in adult patients with acute respiratory distress syndrome (ARDS) whose subphenotype is characterized by less inflammation and lower severity of illness. The... read more

Critical Care Companion: Your Guide To ICU Nursing

Step into the dynamic and demanding world of Intensive Care Unit (ICU) nursing with Critical Care Companion: Your Guide to ICU Nursing by Alysha Edwards. This indispensable guide is crafted to support both novice and experienced... read more

Critical Care Companion: Your Guide To ICU Nursing

The Existence of Adrenal Insufficiency in COVID-19 Patients with Pneumonia

Patients with a history of COVID-19 pneumonia who present with clinical symptoms such as shock, nausea, vomiting, and fatigue should have hypocortisolism included in the differential diagnosis. These patients should also... read more

COVID-19 Infections Are Growing

Large areas of the US are experiencing a significant spread of COVID-19, with the pandemic reaching alarming levels. Data from the Centers for Disease Control and Prevention indicates that the spread of the disease has officially... read more