Palliative Care Consultation and End-of-life Outcomes in Hospitalized COVID-19 Patients

Palliative care consultation was not associated with CPR performed at the end-of-life but was associated with increased incidence of comfort care being utilized. These results suggest that utilizing palliative care consultation... read more

The 1,3,5 Approach to Pediatric Cardiac Arrest

While pediatric cardiac arrests are thankfully rare, their shock waves can seem incalculable. Several studies have outlined the mental health toll that these events can have on everyone involved. There is an appreciable... read more

Lung Ultrasonography Beyond the Diagnosis of Pediatrics Pneumonia

Pneumonia is a prevalent disease with considerable morbidity and mortality among the pediatric population. Early diagnosis and swift commencement of the correct treatment are vital for a favorable clinical outcome. Along... read more

Anticoagulation in COVID-19 Patients

Clinical, laboratory, and autopsy findings support an association between COVID-19 and thromboembolic disease. Acute COVID-19 infection is characterized by mononuclear cell reactivity and pan-endothelialitis, contributing... read more

Ventriculo-Arterial Coupling Analysis Predicts the Hemodynamic Response to Norepinephrine in Hypotensive Postoperative Patients

In patients with arterial hypotension norepinephrine increased end-systolic ventricular elastance and arterial elastance. The effects of norepinephrine on stroke volume depend on baseline ventriculo-arterial coupling. Although... read more

Processed Electroencephalography-guided General Anaesthesia to Reduce Postoperative Delirium

Our primary analysis demonstrated a highly sensitive result with a pooled analysis of trials in which the intervention group adhered to manufacturer's recommended guidelines showing reduced incidence of postoperative delirium... read more

Pediatric Pneumonia Research Priorities in the Context of COVID-19

Operational research on health system capacities, and evaluating optimized delivery of existing treatments, diagnostics and case management approaches are needed. This list should act as a catalyst for collaborative research,... read more

Prophylactic Melatonin for Delirium in Intensive Care (Pro-MEDIC)

Enteral melatonin initiated within 48 h of ICU admission did not reduce the prevalence of delirium compared to placebo. These findings do not support the routine early use of melatonin in the critically ill. A total of... read more

Balanced Fluid Resuscitation for the Critically-Ill: the PLUS study mirrors the BaSICS

Intravenous fluid therapy is one of the most commonly-performed interventions in all of critical care medicine. Numerous trials over the last 20 years have attempted to identify the ideal fluid for those in the intensive... read more

90% of ECMO-eligible COVID-19 Patients Died Amid Rationing

Nearly 90% of adult COVID-19 patients who were eligible for—but didn't receive—extracorporeal membrane oxygenation (ECMO) during the height of the pandemic died in the hospital owing to a lack of resources, even though... read more

Quick Hits in Obstetric Anesthesia

This book provides easy to follow guidance on how to manage emergency situations and common problems in obstetric anesthesia. The book provides different anesthetic recipes for obstetric procedures and describes challenges... read more

Quick Hits in Obstetric Anesthesia

Patients’ Perspectives on Point-of-Care Diagnostics in Acute COPD Exacerbations

Patients' perspectives showed that point-of-care diagnostics and treatment of acute COPD in exacerbation was considered a qualitative offer by the patients and their relatives. At the same time, it was crucial that the emergency... read more

Information Transfer as a Strategy to Improve Safety in ICU

In an Intensive Care Unit (ICU), we attend people with a wide range of pathologies. All the information obtained from monitoring our critical patients, diagnostic and therapeutic techniques, responses to treatments, action... read more

3D Printing PPE During COVID-19 Pandemic

Supply chain disruption during the COVID-19 pandemic has forced healthcare systems to look for alternative ways to meet dramatically increased demand for personal protective equipment (PPE). One potential solution to this... read more

Effect of Intra-arrest Transport, ECPR, and Treatment on Functional Neurologic Outcome

Among patients with refractory out-of-hospital cardiac arrest, the bundle of early intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and invasive assessment and treatment did not significantly improve... read more

POCUS and Digital Tomosynthesis Correlation When Used with COVID-19 Pneumonia Patients

Point-of-care ultrasound (POCUS) in primary care has good sensitivity and specificity when compared to digital tomosynthesis as regards the diagnosis of COVID-19 pneumonia in patients with the clinical suspicion of pulmonary... read more

Cerebral Hypoperfusion Detection with Dynamic Hyperoxia Test

In a heterogeneous population of acute brain-injured patients, cerebral multimodal monitoring with intracranial pressure (ICP) and brain tissue oxygen pressure (PbtO2) detected regional cerebral hypoperfusion with a higher... read more

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

COVID-19 considerably impacted swallowing function in the current study. Although many patients recovered within an acceptable timeframe, some experienced persistent severe dysphagia and a protracted recovery with dependence... read more

Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes

This book discusses the evidence behind the relationship between COVID-19 and heart disease based on emerging state-of-the-art data. The rapid and unexpected global spread of the COVID-19 has revealed proportional levels... read more

Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes

Interdisciplinary Care of Children with Severe Bronchopulmonary Dysplasia

Advances in perinatal care have dramatically improved survival of extremely preterm infants and the incidence of bronchopulmonary dysplasia (BPD) has not changed over the past few decades, which likely reflects the impact... read more

A Cold Case of Superior Vena Cava Syndrome

A 61-year-old woman with hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, congestive heart failure (s/p PPM/ICD), pulmonary embolism (on warfarin), end-stage renal disease (on HD via right internal... read more

Immunotherapy

The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types... read more

Immunotherapy