ARDS Readmissions: A nationwide Cross-sectional Analysis of Epidemiology

Thirty-day readmission occurred in 18.4% of patients with acute respiratory distress syndrome (ARDS) in this sample, and early readmission is strongly associated with increased mortality compared to late readmission. Further... read more

ARDS Readmissions: A nationwide Cross-sectional Analysis of Epidemiology

Sotrovimab Effect Among High-risk COVID-19 Patients

Among nonhospitalized patients with mild to moderate COVID-19 and at risk of disease progression, a single intravenous dose of sotrovimab, compared with placebo, significantly reduced the risk of a composite end point of... read more

Sotrovimab Effect Among High-risk COVID-19 Patients

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

The Pediatric Acute Lung Injury Consensus Conference “at-risk for pediatric acute respiratory distress syndrome” criteria identify critically ill children at high risk of pediatric acute respiratory distress syndrome... read more

Epidemiology and Outcomes of Critically Ill Children at Risk for PARDS

Clinical, Biological and Molecular Aspects of COVID-19

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the... read more

Clinical, Biological and Molecular Aspects of COVID-19

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

COVID-19 considerably impacted swallowing function in the current study. Although many patients recovered within an acceptable timeframe, some experienced persistent severe dysphagia and a protracted recovery with dependence... read more

Clinical Profile and Recovery Pattern of Dysphagia in COVID-19 Patients

ARDS Subphenotypes Validation and Utility Identified by Machine-learning Models

Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. Application of these models can provide valuable prognostic information and could inform management strategies... read more

ARDS Subphenotypes Validation and Utility Identified by Machine-learning Models

High-Dose Dexamethasone vs. Tocilizumab in COVID-19 Pneumonia

Our study findings discourage the use of high doses of dexamethasone in the management of moderate to severe COVID-19 ARDS. The routine use of such high doses to mitigate the inflammatory cytokine storm in these patients... read more

High-Dose Dexamethasone vs. Tocilizumab in COVID-19 Pneumonia

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

The significant mortality rate and prolonged ventilator days associated with invasive mechanical ventilation (IMV) in patients with severe COVID-19 have incited a debate surrounding the use of noninvasive respiratory support... read more

Noninvasive Respiratory Support for COVID-19 Patients: When, for Whom, and How?

Image-Guided Management of COVID-19 Lung Disease

This book offers a detailed and up-to-date overview of image-guided diagnostics in COVID-19 lung disease. A range of image-guided CT and ultrasound procedures in different chest regions are described. For each procedure,... read more

Image-Guided Management of COVID-19 Lung Disease

Pediatric Acute Respiratory Distress Syndrome

This book provides a concise yet comprehensive overview of pediatric acute respiratory distress syndrome (PARDS). The text reviews the emerging science behind the new PARDS definition; explores epidemiology, pathobiology,... read more

Pediatric Acute Respiratory Distress Syndrome

Prone Positioning Effect on Adult Patients Survival Receiving vvECMO for ARDS

This systematic review and meta-analysis of 13 studies (total N = 1836) showed that PP of acute respiratory distress syndrome (ARDS) patients receiving venovenous ECMO (vvECMO) was associated with a significant improvement... read more

Prone Positioning Effect on Adult Patients Survival Receiving vvECMO for ARDS

Bringing Biological ARDS Phenotypes to the Bedside with Machine-learning-based Classifiers

The identification of distinct phenotypes within heterogeneous disease states is a key component of personalised medicine, enabling enrichment of clinical trials, better prognostication, and delivery of tailored treatments... read more

Bringing Biological ARDS Phenotypes to the Bedside with Machine-learning-based Classifiers

Anticoagulation in COVID-19

Thrombotic complications (arterial and venous) are common in patients admitted to hospital with COVID-19 and are an independent predictor of poor outcome. Microvascular thrombi also contribute to organ dysfunction, including... read more

Anticoagulation in COVID-19

Energy Transmission in Mechanically Ventilated Children

Mechanical energy (ME) better related to underlying lung pathology and patient outcome than MP. The delivery of generated energy to the lung was not dependent on endotracheal tube diameter (ETT) size during PC ventilation.... read more

Energy Transmission in Mechanically Ventilated Children

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths worldwide and countless more admissions to hospitals and ICUs. Since... read more

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Principles of Pulmonary Medicine

With an emphasis on the pathophysiologic basis of pulmonary disease, Principles of Pulmonary Medicine, 7th Edition, by Drs. Steven E Weinberger, Barbara A Cockrill, and Jess Mandel, provides a superbly illustrated introduction... read more

Principles of Pulmonary Medicine

Ventilation in Patients with Intra-abdominal Hypertension

The incidence of intra-abdominal hypertension (IAH) is high and still underappreciated by critical care physicians throughout the world. One in four to one in three patients will have IAH on admission, while one out of... read more

Ventilation in Patients with Intra-abdominal Hypertension