Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes

Cardiovascular Complications of COVID-19: Risk, Pathogenesis and Outcomes

This book discusses the evidence behind the relationship between COVID-19 and heart disease based on emerging state-of-the-art data. The rapid and unexpected global spread of the COVID-19 has revealed proportional levels... read more

Ascending Aortic Thrombus After COVID-19 Infection

Ascending Aortic Thrombus After COVID-19 Infection

SARS-CoV-2 predisposes patients to both venous and arterial thromboembolism, including ascending aortic thrombus. The current guidelines for anticoagulation recommend three to six months of continuous anticoagulation... read more

Cancer Treatments Not Associated with Inferior COVID-19 Outcomes

Cancer Treatments Not Associated with Inferior COVID-19 Outcomes

The findings of this study of patients with active cancer suggest that recent systemic anticancer treatments (SACTs) is not associated with inferior outcomes from COVID-19 infection. This has relevance for the care of... read more

Optimal Respiratory Support for COVID-19 Patients

Optimal Respiratory Support for COVID-19 Patients

Noninvasive respiratory support is an essential component of critical care. Both noninvasive ventilation, with its different interface types and modes (including helmet and face masks), and high-flow nasal oxygen (HFNO) are... read more

Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19

Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19

At approximately 4 months after acute illness, cognitive dysfunction, emotional distress, and functional decline were common among a diverse clinical sample of COVID-19 survivors varying in acute illness severity. Patients... read more

Ventilator Capacity Management Queuing Model During COVID-19 Pandemic

Ventilator Capacity Management Queuing Model During COVID-19 Pandemic

We applied a queuing model to inform ventilator capacity planning during the first wave of the COVID-19 epidemic in the province of British Columbia (BC), Canada. The core of our framework is a multi-class Erlang loss model... read more

Ethnic Differences in COVID-19 Mortality in the 2nd and 3rd Waves of the Pandemic in England

Ethnic Differences in COVID-19 Mortality in the 2nd and 3rd Waves of the Pandemic in England

Public health strategies to increase vaccination uptake in ethnic minority groups could reduce disparities in COVID-19 mortality that cannot be accounted for by pre-existing risk factors. Age-adjusted HRs of death involving... read more

Virtual Craniofacial Clinic Outcomes for Assessing Plagiocephaly During the COVID-19 Pandemic

Virtual Craniofacial Clinic Outcomes for Assessing Plagiocephaly During the COVID-19 Pandemic

Virtual clinic encounters resulted in comparable diagnostic accuracy. The trend toward frequent follow-up assessments and changes in the final diagnosis in the virtual clinic cohort has indicated a level of diagnostic uncertainty... read more

Anticoagulation Post-Discharge in Patients Hospitalized Secondary to COVID-19

Anticoagulation Post-Discharge in Patients Hospitalized Secondary to COVID-19

This study contains interesting data that could contribute to the standard of practice when treating patients after hospitalization for COVID-19. However, use caution when applying the results of this study. Several problems... read more

Defining COVID-19 Associated Pulmonary Aspergillosis

Defining COVID-19 Associated Pulmonary Aspergillosis

The reported prevalence of CAPA in ICU patients with COVID-19 varies greatly by study and may be related to surveillance protocols and inconsistent definitions which may inflate the prevalence of this complication. Further... read more

Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis

Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis

Bacterial sepsis patients had early, severe inflammation, profound immune suppression, and life-threatening organ dysfunction that resolved over time; SARS-CoV-2 patients had less severe early inflammation and organ dysfunction... read more

Long-term Cardiovascular Outcomes of COVID-19

Long-term Cardiovascular Outcomes of COVID-19

The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized. Here we used... read more

Critical COVID-19 Pneumonia Determinants

Critical COVID-19 Pneumonia Determinants

SARS-CoV-2 infection is benign in most individuals but, in approx. 10% of cases, it triggers hypoxemic COVID-19 pneumonia, which becomes critical in ˜3% of cases. The ensuing risk of death (˜1%) doubles every five years... read more

COVID-19 Vaccine: Safety and Efficacy

COVID-19 Vaccine: Safety and Efficacy

Two doses of SCB-2019 vaccine plus CpG and alum provides notable protection against the entire severity spectrum of COVID-19 caused by circulating SAR-CoV-2 viruses, including the predominating delta variant. This ongoing... read more

COVID-19 Mortality Prediction Model

COVID-19 Mortality Prediction Model

While there have been extensive analyses characterizing cellular and humoral responses across the severity spectrum in COVID-19, predictors of outcomes within severe COVID-19 remain to be comprehensively elucidated. Recently,... read more

Treating Hypoxia in Discharged COVID-19 Patients

Treating Hypoxia in Discharged COVID-19 Patients

The ICU technique of placing a hypoxic patient in a prone position is being widely used to care for COVID-19 patients in respiratory distress to improve oxygenation and possibly to avoid intubation. The COVID-19 pandemic... read more

Experiences of ICU Nurses with an Innovative Digital Diary Intervention

Experiences of ICU Nurses with an Innovative Digital Diary Intervention

ICU nurses reported that the Post-ICU diary had added value for patients and their relatives. However, in the beginning they also experienced barriers such as lack of time, insufficient integration with their own work processes,... read more