Anticoagulation in COVID-19

Thrombotic complications (arterial and venous) are common in patients admitted to hospital with COVID-19 and are an independent predictor of poor outcome. Microvascular thrombi also contribute to organ dysfunction, including... read more

Anticoagulation in COVID-19

EPs Who Spread Misinformation Could Face Loss of Board Certification

Parallel pandemics have bedeviled the United States since the first cases of COVID-19 were recognized. As cases and deaths surged, so did the misinformation, and those false statements gained credibility when they came from... read more

EPs Who Spread Misinformation Could Face Loss of Board Certification

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Coronavirus disease 2019 (COVID-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths worldwide and countless more admissions to hospitals and ICUs. Since... read more

Quantifying the Burden of Viral Sepsis During the COVID-19 Pandemic and Beyond

Biomarker-guided Steroid Dosing in COVID-19 Pneumonia

Although corticosteroid administration has been associated with improved outcomes in severe COVID-19 pneumonia, their ideal use remains undefined with a "one size fits all" approach used, irrespective of the individual inflammatory... read more

Biomarker-guided Steroid Dosing in COVID-19 Pneumonia

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

An overall good trial that supports the use of high flow oxygen therapy in patients with Severe COVID-19. Randomized controlled trial conducted across three centers in Columbia over 5 months from August 2020 to January... read more

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

Mesenchymal Stem/Stromal Cell-based Therapies for Severe Viral Pneumonia

Severe viral pneumonia is a significant cause of morbidity and mortality globally, whether due to outbreaks of endemic viruses, periodic viral epidemics, or the rarer but devastating global viral pandemics. While limited... read more

Mesenchymal Stem/Stromal Cell-based Therapies for Severe Viral Pneumonia

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

During the COVID-19 pandemic, despite early concerns the impact oral corticosteroids might have on the effects of acute COVID-19 reported by the WHO and the potential severity of disease in patients with asthma and chronic... read more

Prescription Rates Changes for Inhaled Corticosteroids During the COVID-19 Pandemic

Healthcare Worker Safety and COVID-19

It had been apparent from the start of the pandemic that both patients and healthcare workers are at significant risk of acquiring COVID-19 in hospitals. In an early report from Wuhan more than 40% of infections were hospital-acquired,... read more

Healthcare Worker Safety and COVID-19

VTE Diagnosis and Treatment in the COVID-19 Era

This is a very interesting time to be an intensivist with a research interest in blood clots. As such I wanted to use this time to talk about how COVID 19 has changed our approach to diagnostics, therapeutics and even to... read more

VTE Diagnosis and Treatment in the COVID-19 Era

Atlas of Chest Imaging in COVID-19 Patients

This book presents X-ray and CT findings of patients with 2019 Novel Coronavirus (2019-nCoV) pneumonia in early, progressive, critical, and recover stage. It starts with a general review of CT features of new coronavirus... read more

Atlas of Chest Imaging in COVID-19 Patients

Inhaled Amphotericin B Lipid Complex for Prophylaxis Against COVID-19-associated Invasive Pulmonary Aspergillosis

Recently, Prattes and colleagues published in Intensive Care Medicine a high incidence of coronavirus disease 2019-associated invasive pulmonary aspergillosis (CAPA), according to 2020 ECMM/ISHAM consensus criteria, with... read more

Inhaled Amphotericin B Lipid Complex for Prophylaxis Against COVID-19-associated Invasive Pulmonary Aspergillosis

Dynamic Prediction Tool for Mortality in COVID-19 Ventilated Patients

The COVID-19 pandemic has caused intensive care units (ICUs) to reach capacities requiring triage. A tool to predict mortality risk in ventilated patients with COVID-19 could inform decision-making and resource allocation,... read more

Dynamic Prediction Tool for Mortality in COVID-19 Ventilated Patients

High-dose vs. Low-dose Prednisolone in post-COVID-19 Patients

In some patients, respiratory symptoms and imaging abnormalities persist after acute coronavirus disease 2019 (COVID-19) pneumonia. The chest computed tomography (CT) generally shows diffuse parenchymal lung abnormalities... read more

High-dose vs. Low-dose Prednisolone in post-COVID-19 Patients

HSV-1 Reactivation Associated with Increased Mortality Risk and Pneumonia in COVID-19 Patients

Critically ill COVID-19 patients frequently reactivate HSV-1 but not HSV-2. HSV-1 reactivation in critically ill COVID-19 patients was associated with an increased risk of day-60 mortality and hospital-acquired pneumonia... read more

HSV-1 Reactivation Associated with Increased Mortality Risk and Pneumonia in COVID-19 Patients

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

This book is a practical manual for anti-COVID-19. It is not only with the reference to the result of modern medical science, patients' situation, but also take the deployment of medical resources into consideration. Content... read more

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

COVID-19: Limitation of Life-sustaining Treatment and Patient Involvement in Decision-making

Life-sustaining treatment limitation decisions were made for 18% of a COVID-19 patient cohort. Hereof, more than a third of the decisions had been made before hospital admission. Many records lacked information on patient... read more

COVID-19: Limitation of Life-sustaining Treatment and Patient Involvement in Decision-making

UK 28-Day Mortality Trends of COVID-19 Patients

There was a marked deterioration in outcomes for patients admitted to critical care at the peak of the second wave of coronavirus disease 2019 in United Kingdom (December 2020–January 2021), compared with the post-first-wave... read more

UK 28-Day Mortality Trends of COVID-19 Patients

Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients

Among hospitalised COVID-19 patients needing oxygen therapy, high dose of dexamethasone reduced clinical worsening within 11 days after randomisation as compared with low dose of dexamethasone. Further studies are necessary... read more

Effect of High vs. Low Dose of Dexamethasone on COVID-19 Pneumonia Patients