Electrical Impedance Tomography for PEEP Titration in ARDS Patients

ARDS patients may benefit from electrical impedance tomography (EIT)-guided positive end-expiratory pressure (PEEP) titration. The real-time bedside assessment of regional ventilation provided by EIT may result in improved... read more

Association Between Aspirin and AKI in Critical Patients with Chest Trauma

This analysis of two datasets reveals that aspirin usage is associated with an increased risk of acute kidney injury (AKI) in critical patients with chest trauma; however, no significant association was observed between the... read more

Predicting SA-AKI Mortality Using XGBoost Algorithm

The integration of advanced techniques with the XGBoost algorithm yielded a highly accurate and interpretable model for predicting Sepsis-Associated Acute Kidney Injury (SA-AKI) mortality across diverse populations. It... read more

Pharmacokinetics of Opioid Infusions in the Adult ICU Setting

To counter these pharmacokinetics (PKs) alterations, new therapeutic avenues must be further explored in the ICU to individualize opioid infusions. Embase, MEDLINE, PubMed, CINAHL, and Evidence-Based Medicine Reviews (EBMR)... read more

Clinical Efficacy of Nafamostat Mesylate-assisted CRRT Therapy in SA-AKI Patients

Nafamostat Mesylate (NM)-assisted continuous renal replacement therapy (CRRT) therapy significantly improves the therapeutic efficacy of patients with sepsis-associated acute kidney injury (SA-AKI). This combined approach... read more

Impact of Short-Acting Beta-Blockers on the Outcomes of Septic Shock Patients

In patients with septic shock, short-acting beta-blockers may improve survival and reduce new-onset tachyarrhythmias. However, these findings were based on low certainty evidence and given ongoing concerns regarding adverse... read more

Thiamine and Ascorbic Acid in Sepsis and Septic Shock

Exploring the individual and synergistic effects of ascorbic acid and thiamine on key pathways implicated in sepsis pathophysiology has not yielded unequivocal evidence supporting their use without concomitant corticosteroids. Heterogeneity... read more

Evaluation of Vitamin D Supplementation in Critically Ill Patients

Vitamin D supplementation in critically ill patients may shorten ICU or hospital length of stay, improve SOFA scores, or reduce the duration of mechanical ventilation. Its ability to lower 28-day mortality remains uncertain,... read more

ARDS Predictors in ICU Patients with Sepsis Using Dynamic Immune Indicator Changes

This study underscores the pivotal role of dynamic immune indicator changes in predicting acute respiratory distress syndrome (ARDS) development among ICU sepsis patients. By incorporating immune cell and immunoglobulin dynamics... read more

Alcohol Consumption Association with the Risk of Bacterial Infection and Pneumonia

Alcohol consumption has a nonlinear J-shaped dose–response association with the risk of acquiring and dying due to bacterial infection and pneumonia, where moderate consumption between one-half and four UK units per day... read more

Pre-ICU Statin Use, AKI and in Hospital Mortality in Sepsis Patients

Pre-ICU statin therapy is associated with a lower risk of acute kidney injury (AKI), and improved in-hospital survival among obese patients with sepsis, suggesting its potential role as a protective measure in this high-risk... read more

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

This is the first book exploring the unique dynamics created by a multidisciplinary trauma team and how crisis management strategies can improve teamwork and communication and, potentially, improve patient resuscitation... read more

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

The Triglyceride Glucose Index and Delirium Risk in Sepsis Patients

The triglyceride glucose (TyG) index represents a straightforward and efficacious instrument for nursing staff to ascertain the likelihood of delirium in patients with sepsis during the routine monitoring of their condition.... read more

Factors Influencing the Mortality of Patients with Subarachnoid Hemorrhage in the ICU

Spontaneous subarachnoid hemorrhage (SAH) is a prevalent condition for those between the ages of 50 and 60 years, with a high mortality rate in severe cases. The findings of this study indicate that a history of loss... read more

Epidemiology of Myocardial Injury in Trauma Patients

Pathological Troponin concentration elevation occurs in 7% of all trauma patients and it identifies the seriously injured high-risk cohort with worse outcomes than expected based on injury severity. The timing of the... read more

Intensive Care Fundamentals: Practically Oriented Essential Knowledge for Newcomers to ICUs

This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, is a graphical, dense and concise text describing fundamental theoretical concepts needed for doctors and other professionals new... read more

Intensive Care Fundamentals: Practically Oriented Essential Knowledge for Newcomers to ICUs

Prognostic Predictor Using Lactate-to-Albumin Ratio in Patients with Cirrhosis and Sepsis

Lactate-to-albumin ratio (LAR) is strongly associated with poor prognosis in patients with cirrhosis and sepsis. LAR is a promising prognostic marker that provides clinicians with a simple and effective tool for risk... read more

Machine Learning to Predict Extubation Success Using the SBT

Among the predictive models that used MOT, VCD, and the spontaneous breathing trial (SBT) as input variables through five machine learning techniques, decision trees and artificial neural networks demonstrated the best diagnostic... read more

Late Hemorrhagic Complication and Unilateral Neck Edema Related to Cannulation in VV-ECMO

This is a rare case of delayed acute unilateral neck edema that developed during veno-venous extracorporeal membrane oxygenation (VV-ECMO). This case underscores the importance of considering a wide range of differential... read more

Non-invasive ICP Monitoring for TBI Patients When Invasive Systems Not Available

Using a mixed-method approach involving literature review and an in-person consensus by experts, a set of recommendations designed to assist clinicians managing traumatic brain injury (TBI) patients using nICP systems plus... read more

POCUS-first vs. CT-first Approach on ED LOS in Patients with Acute Cholecystitis

While point-of-care ultrasound (PoCUS)-first and computed tomography (CT)-first approaches resulted in comparable emergency department (ED) length of stay (LOS) and time to surgical consultation for patients with mild AC,... read more

Mortality Predictor with sPAP in Elderly Critically Ill with Severe COVID-19 Pneumonia

Mortality in general ARDS patients remains high, with many experiencing long-lasting sequelae. Numerous studies have been conducted to identify predictors of mortality in COVID-19 patients, particularly regarding right ventricular... read more