Emergency Department Disposition and Mortality in COVID‐19 Patients with ARDS

Compared to direct ICU admission, admission from the ED to the ward is associated with increased mortality in patients who meet COVID‐19 ARDS criteria during their hospitalization, despite lower 4C and similar SAPS‐III... read more

Endothelial Dysfunction and Persistent Inflammation in Severe Post-COVID-19 Patients

Six months after ICU discharge from severe ARDS secondary to COVID-19, patients with gas exchange impairment exhibit evidence of systemic inflammation, along with elevated ICAM-1 levels, ultimately resulting in increased... read more

Cardiac Arrest During a Ferric Derisomaltose Infusion Followed by Complete Heart Block

Bradycardia and heart block are rarely reported in the parenteral iron literature. Although rare, it may be reasonable to consider parenteral iron as a toxicological etiology for patients presenting with complete heart block... read more

Weaning From Mechanical Ventilation in ICUs Across 50 Countries

Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients... read more

Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients

Among adults receiving mechanical ventilation in the ICU, adding early in-bed Cycling to usual physiotherapy did not improve physical function at 3 days after discharge from the ICU compared with Usual physiotherapy alone.... read more

Mechanical Ventilation in the ICU: A New Approach and Treatment

Mechanical Ventilation in the ICU: A New Approach and Treatment

In the present book, a broad description of the processes carried out in patients with mechanical ventilation in the ICU is made. It covers from an overview of mechanical ventilation and some of its history to the processes... read more

Secretomic Approach Value for Distinguishing Patients with COVID-19 Viral Pneumonia Among ICU Patients with Respiratory Distress

In intensive care units, COVID-19 viral pneumonia patients (VPP) present symptoms similar to those of other patients with Nonviral infection (NV-ICU). To better manage VPP, it is therefore interesting to better understand... read more

Early vs. Delayed Enteral Nutrition in ICU Sepsis Patients

Early enteral nutrition may not affect mortality rates when analyzed using propensity score matching. However, our findings indicate that early enteral nutrition is associated with shorter ICU stays and a lower incidence... read more

Immunosuppression Not Associated with a Higher Incidence of ICU-acquired Bacterial Bloodstream Infections

Immunosuppression Not Associated with a Higher Incidence of ICU-acquired Bacterial Bloodstream Infections

In this monocentric, retrospective observational cohort study, the incidence of ICU-acquired bacterial BSI was not different between immunocompromised and non-immunocompromised patients. This suggests that the clinical... read more

Workbook on Renal Replacement Therapy in ICU (ISCCM)

Workbook on Renal Replacement Therapy in ICU (ISCCM)

This workbook focuses on renal replacement therapy in ICU. The incidence of acute kidney injury in critically ill patients is increasing steeply. Acute kidney injury in this setting is associated with high morbidity and mortality.... read more

Incidence of AKI and attributive mortality in ARDS randomized trials

Incidence of AKI and attributive mortality in ARDS randomized trials

The development of acute kidney injury (AKI) after the acute respiratory distress syndrome (ARDS) reduces the chance of organ recovery and survival. The purpose of this study was to examine the AKI rate and attributable mortality... read more

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Handbook of Drugs in Intensive Care: An A-Z Guide

Handbook of Drugs in Intensive Care: An A-Z Guide

Now in its sixth edition, the Handbook of Drugs in Intensive Care is the essential guide to using drugs safely and effectively in the intensive care setting. The book is split into two sections: an A-Z guide to the drugs... read more

Nursing Care and ECMO

Nursing Care and ECMO

This highly informative book provides essential insights for ICU nurses at ECMO centers around the world, who face the substantial challenges involved in the management of ECMO patients. Above all, it meets their training... read more

Sepsis: Definitions, Pathophysiology and the Challenge of Bedside Management

Sepsis: Definitions, Pathophysiology and the Challenge of Bedside Management

A comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike. Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall... read more

Hepatorenal Syndrome in the ICU

Hepatorenal Syndrome in the ICU

Patients with cirrhosis are susceptible to develop acute kidney injury (AKI), a complication that occurs in up to 50% of hospitalized patients [80% in the intensive care unit (ICU)], and has been associated with increased... read more

Sepsis Mortality Among ICU Patients with Hematological Malignancy

Sepsis Mortality Among ICU Patients with Hematological Malignancy

Over the past two decades, there have been substantial improvements in mortality in hematological malignancy patients with sepsis, including across all levels of illness severity and in patients requiring mechanical ventilation.... read more