Outcomes of Neonates Born to Mothers With Severe COVID-19

Outcomes of Neonates Born to Mothers With Severe COVID-19

In this cohort study, no evidence of vertical transmission of SARS-CoV-2 was identified in the first 101 newborns born to mothers positive for or with suspected SARS-CoV-2 infections at a large medical center in an epicenter... read more

Standardized Perioperative Feeding Protocol Improves Outcomes

Standardized Perioperative Feeding Protocol Improves Outcomes

An aggressive, but safe, perioperative feeding protocol implemented in a homogenous low-risk neonatal cardiac surgical population improves feeding outcomes, including increased weight gain, as well as decreased postoperative... read more

Dual Therapy Using Sildenafil and Milrinone Superior to Monotherapy in Neonates with Severe PPHN

Dual Therapy Using Sildenafil and Milrinone Superior to Monotherapy in Neonates with Severe PPHN

Dual therapy using sildenafil and milrinone was superior to monotherapy with either drug in neonates with severe persistent pulmonary hypertension (PPHN) and is recommended for use in resource-constrained settings. A double-blind... read more

Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children

Comparison of Clinical Features of COVID-19 vs Seasonal Influenza A and B in US Children

In this cohort study of 315 children with COVID-19 and 1402 children with seasonal influenza, there were no statistically significant differences in the rates of hospitalization, admission to the intensive care unit, and... read more

Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs

Use and Outcomes of Nasotracheal Intubation Among Patients Requiring Mechanical Ventilation Across U.S. PICUs

Nasotracheal intubation is used in a minority of U.S. PICUs and mainly among young cardiac patients. Nasotracheal intubation is associated with a lower rate of unplanned extubations in this patient population. Future... read more

Factors Behind Decline of VV ECMO to Support Neonatal Respiratory Failure

Factors Behind Decline of VV ECMO to Support Neonatal Respiratory Failure

The majority of U.K. centers are unable to provide venovenous extracorporeal membrane oxygenation (VV ECMO) for neonates due to concerns with availability and suitability of dual lumen cannulae. An alternative to be considered... read more

Survey Finds More Than Half of Pediatric Cardiology Nurses Are Burned Out

Survey Finds More Than Half of Pediatric Cardiology Nurses Are Burned Out

More than half of nurses caring for children with cardiovascular conditions are emotionally exhausted and good working environments were linked with less burnout, according to a survey presented during ESC Congress 2020. Of... read more

Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children

Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children

Acute myocarditis with intense systemic inflammation and atypical Kawasaki disease is an emerging severe pediatric disease following SARS-CoV-2 infection. Early recognition of this disease is needed and referral to an expert... read more

A Randomised Trial of High-flow Nasal Cannula in Infants with Moderate Bronchiolitis

A Randomised Trial of High-flow Nasal Cannula in Infants with Moderate Bronchiolitis

In patients with moderate bronchiolitis, there was no evidence of lower rate of escalating respiratory support among those receiving HFNC therapy. The analyses included 268 patients among the 2621 infants assessed for... read more

Pediatric Critical Care and COVID-19

Pediatric Critical Care and COVID-19

We provide early clinical and laboratory data about critical pediatric COVID-19, which suggest a variable disease but generally good outcomes compared with adults. Targets for research include the course of organ failure... read more

Holding and Mobility of Pediatric Patients With Transthoracic Intracardiac Catheters

Holding and Mobility of Pediatric Patients With Transthoracic Intracardiac Catheters

Pediatric patients with transthoracic intracardiac catheters can be safely held and mobilized out of bed. A total of 1,358 patients had activity and positioning documented while transthoracic intracardiac catheters were... read more

Hypothermia Plus Melatonin in Asphyctic Newborns

Hypothermia Plus Melatonin in Asphyctic Newborns

The early addition of IV melatonin to asphyctic neonates is feasible and may improve long-term neurodevelopment. To our knowledge, this is the first clinical trial to analyze the administration of IV melatonin as an adjuvant... read more

Development of Persistent Respiratory Morbidity in Previously Healthy Children After ARF

Development of Persistent Respiratory Morbidity in Previously Healthy Children After ARF

Persistent respiratory morbidity develops in up to potentially 44% of previously healthy children less than or equal to 24 months old at follow-up after acute respiratory failure (ARF) requiring mechanical ventilation. This... read more

High Breath-by-Breath Variability Is Associated With Extubation Failure in Children

High Breath-by-Breath Variability Is Associated With Extubation Failure in Children

High respiratory variability during spontaneous breathing trials is independently associated with extubation failure in children, with very high rates of extubation failure when these children develop postextubation upper... read more