Change in Out-of-Hospital 12-lead ECG Diagnostic Classification in Patients Resuscitated From OHCA

Change in 12-lead ECG classification from OH to ED setting in patients resuscitated from out-of-hospital cardiac arrest (OHCA) was common (49%). The OH STEMI classification changed to a less ischemic (non-STEMI) ED classification... read more

Saline vs. Balanced Crystalloid in Patients with Diabetic Ketoacidosis

In patients with diabetic ketoacidosis (DKA), the use of saline may be associated with longer time to DKA resolution, higher post-resuscitation serum chloride levels, lower post-resuscitation serum bicarbonate levels, and... read more

Extracorporeal Cardiopulmonary Resuscitation (ECPR) in Adults

Rates of survival with functional recovery for both in-hospital and out-of-hospital cardiac arrest are notably low. Extracorporeal cardiopulmonary resuscitation (ECPR) is emerging as a modality to improve prognosis by augmenting... read more

A New Acronym to Select Eligible Patients for ECPR

Rhythm check three - A2BCDE3! - A new acronym to select eligible patients for extracorporeal cardiopulmonary resuscitation (eCPR) Extracorporeal cardiopulmonary resuscitation (eCPR) is an ultra-invasive approach for the... read more

High resuscitative endovascular balloon occlusion of the aorta procedural volume is associated with improved outcomes

Resuscitative endovascular balloon occlusion of the aorta survival is increased at high versus low utilization centers. Increased experience with REBOA may be associated with earlier deployment and subsequently improved patient... read more

Which Injured Patients with Moderate Fibrinogen Deficit Need Fibrinogen Supplementation?

We have shown in this study an association between shock parameters and fibrinogen administration. Further studies are needed to determine how these parameters may be used to guide fibrinogen administration in trauma patients... read more

Feasibility of Conservative Fluid Administration and Deresuscitation vs. Usual Care

A strategy of conservative fluid administration and active deresuscitation is feasible, reduces fluid balance compared with usual care, and may cause benefit or harm. In view of wide variations in contemporary clinical... read more

Neurological Outcomes in Patients with OHCA who received ECPR

Little is known about the difference in outcomes between young and old patients who received extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA). Therefore, we aimed to investigate... read more

Severe Hyponatremia Management with DDAVP Clamp-Bolus Technique

The DDAVP clamp technique has considerably simplified the management of severe hyponatremia. The DDAVP clamp was a substantial step forwards in the management of severe hyponatremia. It eliminated a lot of the variability... read more

POCUS in Cardiorespiratory Arrest

The POCUS-CA (Point-of-care ultrasound in cardiac arrest) is a diagnostic tool in the Intensive Care Unit and Emergency Department setting. The literature indicates that in the patient in a cardiorespiratory arrest it... read more

Effect of Adjunctive Vitamin C, Glucocorticoids, and Vitamin B1 on Sepsis

We aimed to compare the effects of vitamin C, glucocorticoids, vitamin B1, combinations of these drugs, and placebo or usual care on longer-term mortality in adults with sepsis or septic shock. MEDLINE, Embase, CENTRAL, ClinicalTrials.gov... read more

Point of Care Venous Doppler Ultrasound

Accurate assessment of the hemodynamic status is vital for appropriate management of patients with critical illness. As such, there has been a constant quest for reliable and non-invasive bedside tools to assess and monitor... read more

A Novel Anatomic Landmark to Target the LV During Chest Compressions in Cardiac Arrest

A novel area of compression over the left sternal border at the inter-nipple line would result in compressions over the LV in nearly three-quarters of our study participants. Future research should investigate whether... read more

Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest

Low levels of brain injury markers in blood are associated with good neurological outcome after CA. Incorporating biomarkers into neuroprognostication may help prevent premature withdrawal of life-sustaining therapy. Retrospective... read more

Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock

In patients with cardiogenic shock, no significant difference between Milrinone and Dobutamine was found with respect to the primary composite outcome or important secondary outcomes. A total of 192 participants (96 in... read more

Use of Bivalirudin for Anticoagulation in Pediatric ECMO

This study describes the use of bivalirudin in children on extracorporeal membrane oxygenation (ECMO). Pediatric patients receiving bivalirudin were compared to patients receiving heparin as the anticoagulant on ECMO. Data... read more

Reliability of Mechanical Ventilation During Continuous Chest Compressions

All investigated transport ventilators were able to provide alveolar ventilation even though chest compressions considerably decreased tidal volumes. Our results support the concept of using ventilators to avoid excessive... read more

Do Not Attempt CPR Decisions in People Admitted with Suspected COVID-19

Early do not attempt cardiopulmonary resuscitation (DNACPR) decisions were associated with recognised predictors of adverse outcome, and were inversely associated with Asian ethnicity. Most people with an early DNACPR decision... read more

Standardized post-resuscitation damage assessment of two mechanical chest compression devices

The LUCAS 2 device shows superior resuscitation outcomes and less thoracic injuries compared to Corpuls cpr when used for experimental CPR in juvenile pigs. Researchers should be aware that different mCCDs for experimental... read more

Effects of 5% Albumin Plus Saline vs. Saline Alone on Outcomes From Large-Volume Resuscitation in Critically Ill Patients

During large-volume resuscitation, 5% albumin was associated with reduced mortality and major adverse kidney event at 30, 90, and 365 days. However, a higher rate of acute kidney injury of any stage was observed that did... read more

A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients with COVID-19

Approximately, one in 20 patients hospitalized with coronavirus disease 2019 received resuscitation for an in-hospital cardiac arrest. Hospital survival after in-hospital cardiac arrest within the ICU was higher than non-ICU... read more

Factors Associated With Initiation of ECPR in the Pediatric Population

Although extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly utilized in the pediatric critical care environment, our understanding regarding pediatric candidacy for ECPR remains unknown. Our objective... read more