Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock

In patients with cardiogenic shock, no significant difference between Milrinone and Dobutamine was found with respect to the primary composite outcome or important secondary outcomes. A total of 192 participants (96 in... read more

Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock

Use of Bivalirudin for Anticoagulation in Pediatric ECMO

This study describes the use of bivalirudin in children on extracorporeal membrane oxygenation (ECMO). Pediatric patients receiving bivalirudin were compared to patients receiving heparin as the anticoagulant on ECMO. Data... read more

Use of Bivalirudin for Anticoagulation in Pediatric ECMO

Reliability of Mechanical Ventilation During Continuous Chest Compressions

All investigated transport ventilators were able to provide alveolar ventilation even though chest compressions considerably decreased tidal volumes. Our results support the concept of using ventilators to avoid excessive... read more

Reliability of Mechanical Ventilation During Continuous Chest Compressions

Do Not Attempt CPR Decisions in People Admitted with Suspected COVID-19

Early do not attempt cardiopulmonary resuscitation (DNACPR) decisions were associated with recognised predictors of adverse outcome, and were inversely associated with Asian ethnicity. Most people with an early DNACPR decision... read more

Do Not Attempt CPR Decisions in People Admitted with Suspected COVID-19

Standardized post-resuscitation damage assessment of two mechanical chest compression devices

The LUCAS 2 device shows superior resuscitation outcomes and less thoracic injuries compared to Corpuls cpr when used for experimental CPR in juvenile pigs. Researchers should be aware that different mCCDs for experimental... read more

Standardized post-resuscitation damage assessment of two mechanical chest compression devices

Effects of 5% Albumin Plus Saline vs. Saline Alone on Outcomes From Large-Volume Resuscitation in Critically Ill Patients

During large-volume resuscitation, 5% albumin was associated with reduced mortality and major adverse kidney event at 30, 90, and 365 days. However, a higher rate of acute kidney injury of any stage was observed that did... read more

Effects of 5% Albumin Plus Saline vs. Saline Alone on Outcomes From Large-Volume Resuscitation in Critically Ill Patients

A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients with COVID-19

Approximately, one in 20 patients hospitalized with coronavirus disease 2019 received resuscitation for an in-hospital cardiac arrest. Hospital survival after in-hospital cardiac arrest within the ICU was higher than non-ICU... read more

A Systematic Review of the Incidence and Outcomes of In-Hospital Cardiac Arrests in Patients with COVID-19

Factors Associated With Initiation of ECPR in the Pediatric Population

Although extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly utilized in the pediatric critical care environment, our understanding regarding pediatric candidacy for ECPR remains unknown. Our objective... read more

Factors Associated With Initiation of ECPR in the Pediatric Population

Quantitative Characterization of LV Function During Pulseless Electrical Activity Using Echocardiography

Left ventricular function measured by LVFS is positively correlated with higher probability of rates of return of spontaneous circulation (ROSC) and may be associated with higher chances of survival in patients with PEA arrest. We... read more

Quantitative Characterization of LV Function During Pulseless Electrical Activity Using Echocardiography

Variation in Pediatric Palliative Care Allocation Among Critically Ill Children in the United States

Palliative care consultation for critically ill children in the United States is low. Palliative care utilization is increasing but considerable variation exists across institutions, suggesting inequity in palliative care... read more

Variation in Pediatric Palliative Care Allocation Among Critically Ill Children in the United States

Economical provision of blood components for critical patient transport across a large geographic area

With appropriate attention to detail, it is possible to provide life-saving blood components to aeromedical transport services across a large geographic area with efficient blood component usage, minimal blood wastage, and... read more

Economical provision of blood components for critical patient transport across a large geographic area

A novel, hands-free ultrasound patch for continuous monitoring of quantitative Doppler in the carotid artery

Quantitative Doppler ultrasound of the carotid artery has been proposed as an instantaneous surrogate for monitoring rapid changes in left ventricular output. Tracking immediate changes in the arterial Doppler spectrogram... read more

A novel, hands-free ultrasound patch for continuous monitoring of quantitative Doppler in the carotid artery

Confirming a Pulse during Resuscitation

Much has been written about using ultrasound in cardiac arrest. The REASON study found that identification of cardiac standstill in PEA or asystole is correlated with almost no chance of meaningful recovery and can assist... read more

Confirming a Pulse during Resuscitation

Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children

Non-resuscitation fluid in excess of hydration requirements is associated with increased mortality in critically ill children. Excess maintenance fluid is a modifiable contributor to this fluid volume. Strategies to reduce... read more

Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children

The Surviving Sepsis Campaign: Fluid Resuscitation and Vasopressor Therapy Research Priorities in Adult Patients

In the second of a series of manuscripts subsequent to the original article, members with expertise in the subjects expound upon the three identified priorities related to fluid resuscitation and vasopressor therapies. This... read more

The Surviving Sepsis Campaign: Fluid Resuscitation and Vasopressor Therapy Research Priorities in Adult Patients

Increase in PI during PLR detects a positive response of the PLR test

An increase in perfusion index (PI) during passive leg raising (PLR) by 9% accurately detects a positive response of the PLR test. Three patients were excluded because the plethysmography signal was absent and 3 other... read more

Increase in PI during PLR detects a positive response of the PLR test

Pediatric Extracorporeal Cardiopulmonary Resuscitation ELSO Guidelines

Survival rates with good neurologic outcomes following conventional cardiopulmonary resuscitation (CPR) for cardiopulmonary arrest, either in the in-hospital (IH) or out-of-hospital settings, have improved but remain poor... read more

Pediatric Extracorporeal Cardiopulmonary Resuscitation ELSO Guidelines

EROCA: Results of a Randomized Feasibility Trial of Expedited Out-of-Hospital Transport

Outcomes of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest depend on time to therapy initiation. We hypothesize that it would be feasible to select refractory out-of-hospital cardiac... read more

EROCA: Results of a Randomized Feasibility Trial of Expedited Out-of-Hospital Transport

Association between the BMI and outcomes of patients resuscitated from OHCA

The body mass index (BMI) was not independently associated with favourable neurologic and survival outcomes of patients surviving from out-of-hospital cardiac arrest (OHCA). Nine hospitals were enrolled; finally, 605 patients... read more

Association between the BMI and outcomes of patients resuscitated from OHCA

Overcoming Enteral Nutrition Delivery Challenges in Critical Care

It is the essential implementation of this new evidence occurs to overcome real and perceived EN challenges. This data should lead to increased standardization/protocolization of ICU nutrition therapy to ensure personalized... read more

Overcoming Enteral Nutrition Delivery Challenges in Critical Care

The Impact of Defibrillation on Aerosol Generation During CPR

Chest compressions alone did not cause significant aerosol generation in this swine model. However, increased aerosol generation was detected during chest compression immediately following defibrillation. Additional research... read more

The Impact of Defibrillation on Aerosol Generation During CPR