Critical Care Pediatric Nephrology and Dialysis

Critical Care Pediatric Nephrology and Dialysis

This book covers all key aspects of critical care in pediatric nephrology, including acute dialysis in sick children. It also provides detailed protocols for managing fluid and electrolyte balance and dialysis in children... read more

Critical Care Nephrology and Renal Replacement Therapy in Children

Critical Care Nephrology and Renal Replacement Therapy in Children

Pediatric critical care nephrology is a complex and highly specialized field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time... read more

Prevalence and Risk Factors of ICU-acquired Weakness in COVID-19 Patients

The prevalence of ICUAW in patients with COVID-19 was considered relatively high. Older age, pre-existing hypertension, medical intervention of prone position, NMBA use, needed tracheostomy and RRT were likely risk factors.... read more

Citrate Anticoagulation for CRRT

Regional citrate anticoagulation (RCA) is a viable option for liver failure patients. The pro-posed inducible metabolic pathway hypothesis challenges the belief in hepatic dominance over citrate metabolism during RCA-CRRT.... read more

Efficacy of β-Blockers in Decreasing Mortality in Sepsis and Septic Shock Patients

This study suggests that the use of β-blockers in sepsis and septic shock patients is associated with a significant decrease in in-hospital mortality and also associated with better patient outcomes. As β-blockers cause... read more

Early Ketamine Sedation Outcomes Among Mechanically Ventilated COVID-19 Patients

In a diverse sample of U.S. hospitals, about one in 30 patients mechanically ventilated with COVID-19 received ketamine infusions. Early ketamine may have an association with higher hospital mortality, increased total cost,... read more

Workbook on Renal Replacement Therapy in ICU (ISCCM)

Workbook on Renal Replacement Therapy in ICU (ISCCM)

This workbook focuses on renal replacement therapy in ICU. The incidence of acute kidney injury in critically ill patients is increasing steeply. Acute kidney injury in this setting is associated with high morbidity and mortality.... read more

Hepatorenal Syndrome in the ICU

Hepatorenal Syndrome in the ICU

Patients with cirrhosis are susceptible to develop acute kidney injury (AKI), a complication that occurs in up to 50% of hospitalized patients [80% in the intensive care unit (ICU)], and has been associated with increased... read more

AKI Risk Factors in ICU Patients Using Colistin

AKI Risk Factors in ICU Patients Using Colistin

Colistin, an antibiotic of polymyxin group, has recently been increasingly used in the treatment of multidrug resistant gram-negative bacteria. However, it has serious adverse effects such as acute kidney injury (AKI). We... read more

Ilofotase Alfa Doesn’t Improved Survival Among Critically Ill Patients with SA-AKI

Ilofotase Alfa Doesn’t Improved Survival Among Critically Ill Patients with SA-AKI

Sepsis-associated acute kidney injury (SA-AKI) in patients admitted to an intensive care unit is associated with significant morbidity and mortality. There is currently no pharmaceutical treatment. Although we found no... read more

ECPR for Hypothermic Refractory Cardiac Arrests in Temperate Climates

ECPR for Hypothermic Refractory Cardiac Arrests in Temperate Climates

Accidental hypothermia designates an unintentional drop in body temperature below 35 °C. There is a major risk of ventricular fibrillation below 28 °C and cardiac arrest is almost inevitable below 24 °C. In such cases,... read more

Propofol-Related Infusion Syndrome in a Child with RSE

Propofol-Related Infusion Syndrome in a Child with RSE

Propofol is used for sedation, anxiolysis, anesthesia induction, and as an anticonvulsant. In cases of refractory status epilepticus (RSE), propofol is more efficient than barbiturates. We present a case of a 3-year-old... read more

Initiation of CRRT vs. Intermittent Hemodialysis in Critically Ill Patients with Severe AKI

Initiation of CRRT vs. Intermittent Hemodialysis in Critically Ill Patients with Severe AKI

In critically ill patients with severe acute kidney injury (AKI), initiation of continuous renal replacement therapy (CRRT), as compared to intermittent hemodialysis (IHD), was associated with a significant reduction in the... read more

Optimal RRT for Critically Ill Patients with Severe AKI

Optimal RRT for Critically Ill Patients with Severe AKI

In critically ill patients with severe acute kidney injury (AKI), initiation of continuous renal replacement therapy (CRRT), as compared to intermittent hemodialysis (IHD), was associated with a significant reduction in the... read more

Renal Replacement Therapy: Controversies and Future Trends

Renal Replacement Therapy: Controversies and Future Trends

Controversies and trends have always been present in nephrology. Since its inception and throughout its development, renal replacement therapy has been shrouded in uncertainty, even as it advances, and it has always been... read more

Doppler Ultrasound Identified Venous Congestion in Septic Shock

Doppler Ultrasound Identified Venous Congestion in Septic Shock

Venous congestion is a pathophysiological state where high venous pressures cause organ edema and dysfunction. Venous congestion is associated with worse outcomes, particularly acute kidney injury (AKI), for critically ill... read more

Prostacyclin Anticoagulation Efficacy in Critically Ill Patients Requiring Extracorporeal Support

Prostacyclin Anticoagulation Efficacy in Critically Ill Patients Requiring Extracorporeal Support

Extracorporeal support modalities are highly prothrombotic. Anticoagulation is frequently used for patients receiving Continuous Renal Replacement Therapy (CRRT), Molecular Adsorbent Recirculating System (MARS), and Extracorporeal... read more