Vasopressin for Acute Hemorrhage?

Vasoactive medications are one of the pillars of management of shock in Emergency Departments. Inopressors, namely Norepinephrine and Epinephrine, are the two most commonly used pressors in US Emergency Departments, used... read more

Vasopressin for Acute Hemorrhage?

Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury

Cardiac dysfunction (CD) importantly contributes to mortality in trauma patients, who survive their initial injuries following successful hemostatic resuscitation. This poor outcome has been correlated with elevated biomarkers... read more

Modeling Cardiac Dysfunction Following Traumatic Hemorrhage Injury

The Protective Effects of Regional Hypothermia on Injured Limbs Combined with Hemorrhagic-shock & Tourniquet

The aim of this study is to investigate the protective effects of regional hypothermia (RH) on rabbits' limbs injured by a steel-ball combined with hemorrhagic-shock, and then employed tourniquet over-time, tried to identify... read more

The Protective Effects of Regional Hypothermia on Injured Limbs Combined with Hemorrhagic-shock & Tourniquet

Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes

In this multicenter cohort, ventilation rates exceeding guidelines were common. Among the range of rates delivered, higher rates were associated with improved survival to hospital discharge. Arterial blood pressure and... read more

Ventilation Rates and Pediatric In-Hospital Cardiac Arrest Survival Outcomes

Critical Care Doctors Placed Humans in Suspended Animation For The First Time

Critical care doctors have placed humans in suspended animation for the first time, as part of a trial in the US that aims to make it possible to fix traumatic injuries that would otherwise cause death. Samuel Tisherman,... read more

Critical Care Doctors Placed Humans in Suspended Animation For The First Time

Left Ventricular Wall Findings in Non-electrocardiography-gated CE-CT After ECPR

Few studies have reported left ventricular wall findings in contrast-enhanced computed tomography (CE-CT) after extracorporeal cardiopulmonary resuscitation (ECPR). This study examined left ventricular wall CE-CT findings... read more

Left Ventricular Wall Findings in Non-electrocardiography-gated CE-CT After ECPR

Use of Vasopressor Increases the Risk of Mortality in Traumatic Hemorrhagic Shock

Use of vasopressor for traumatic hemorrhagic shock was associated with mortality after controlling for biases (trauma severity; volume of fluid resuscitation). Among 236,698 trauma patients, 3,551 were included in the... read more

Use of Vasopressor Increases the Risk of Mortality in Traumatic Hemorrhagic Shock

Lactate and Stepwise Lactate Kinetics Used to Guide Resuscitation

Lactate is an important parameter for monitoring tissue perfusion at present. Lactate kinetics are particularly important to evaluate the response of ICU patients. Therefore, lactate can be the starting point for resuscitation,... read more

Lactate and Stepwise Lactate Kinetics Used to Guide Resuscitation

Cardiac Intensive Care

Using a multidisciplinary, team-oriented approach, this unique title expertly covers all the latest approaches to the assessment, diagnosis, and treatment of patients with critical cardiac illness. Led by Dr David L. Brown,... read more

Cardiac Intensive Care

Dispatcher-assisted Cardiopulmonary Resuscitation for Traumatic Patients with OHCA

Dispatcher-assisted cardiopulmonary resuscitation (DA-CPR) was not associated with better outcomes for traumatic out-of-hospital cardiac arrests (OHCA) in achieving a short-term sustained return of spontaneous circulation... read more

Dispatcher-assisted Cardiopulmonary Resuscitation for Traumatic Patients with OHCA

Fluid Resuscitation: Evidence-based Solutions?

Intravenous (IV) fluid prescribing is one of the commonest tasks carried out by junior doctors. I still remember around this time last year when I was fresh out of medical school and had just been let loose on the wards,... read more

Fluid Resuscitation: Evidence-based Solutions?

Early vs. Delayed Administration of Norepinephrine in Patients with Septic Shock

This study investigated the incidence of delayed norepinephrine administration following the onset of septic shock and its effect on hospital mortality. Our results show that early administration of norepinephrine in... read more

Early vs. Delayed Administration of Norepinephrine in Patients with Septic Shock

Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm

Among patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm, moderate therapeutic hypothermia at 33°C for 24 hours led to a higher percentage of patients who survived with a favorable... read more

Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm

Early Prognostication of Neurological Outcome by HRV in Adults with Out-of-Hospital Sudden Cardiac Arrest

The present data indicate that heart rate variability (HRV) analysis could be useful for early prognostication for comatose patients during hypothermic TTM within 24 h after ROSC. The value of HRV as a prognosticator... read more

Early Prognostication of Neurological Outcome by HRV in Adults with Out-of-Hospital Sudden Cardiac Arrest

Healthcare Provider Perceptions of Cardiopulmonary Resuscitation Quality During Simulation Training

Cardiopulmonary resuscitation performance during mock codes does not meet the American Heart Association's quality recommendations. Healthcare providers have poor insight into the quality of cardiopulmonary resuscitation... read more

Healthcare Provider Perceptions of Cardiopulmonary Resuscitation Quality During Simulation Training

Vasoactive Medication and Randomized Clinical Trials

Vasoactive medication is one of the cornerstones in the treatment of critically ill patients in shock. Shock can be defined as a failure of the circulatory system to provide adequate tissue perfusion resulting in cellular... read more

Vasoactive Medication and Randomized Clinical Trials

Pericardiocentesis During Cardiopulmonary Resuscitation

In this video, Dr. Traci Wolbrink reviews the procedural steps to performing Pericardiocentesis as well as reviewing indications, contraindications and risk factors for patients experiencing pericardial effusion. ... read more

Pericardiocentesis During Cardiopulmonary Resuscitation

Prehospital cardiopulmonary resuscitation duration and neurological outcome after out-of-hospital cardiac arrest among children by location of arrest

A longer prehospital EMS CPR duration is independently associated with a lower proportion of patients with a favorable neurological outcome. The association between prehospital EMS CPR duration and neurological outcome... read more

Prehospital cardiopulmonary resuscitation duration and neurological outcome after out-of-hospital cardiac arrest among children by location of arrest

Identification of Subclasses of Sepsis that Showed Different Clinical Outcomes and Responses to Amount of Fluid Resuscitation

Sepsis is a heterogeneous disease and identification of its subclasses may facilitate and optimize clinical management. This study aimed to identify subclasses of sepsis and its responses to different amounts of fluid resuscitation.... read more

Identification of Subclasses of Sepsis that Showed Different Clinical Outcomes and Responses to Amount of Fluid Resuscitation

A Compression Method to Reduce Fluid Balance of Septic Shock Patients

This article presents a close look at the Corporeal Compression at the Onset of Septic shock (COCOONs). Fluid overload in septic intensive care unit (ICU) patients is common and strongly associated with poor outcome. There... read more

A Compression Method to Reduce Fluid Balance of Septic Shock Patients

Emergency Department Resuscitation of the Critically Ill

A crash course in Critical Care! Stabilize, treat, and save your sickest patients in the ed or the field – with ACEP's ultimate resuscitation guide. packed with succinct evidence-based chapters written by the nation's foremost... read more

Emergency Department Resuscitation of the Critically Ill