Prehospital On-scene Anesthetist Treating Severe TBI Patients is Associated with Lower Mortality and Better Neurological Outcome

Prehospital On-scene Anesthetist Treating Severe TBI Patients is Associated with Lower Mortality and Better Neurological Outcome

Patients with isolated traumatic brain injury (TBI) are likely to benefit from effective prehospital care to prevent secondary brain injury. Only a few studies have focused on the impact of advanced interventions in TBI... read more

Impact of Paralytic Agent on Postintubation Sedation

Impact of Paralytic Agent on Postintubation Sedation

The aim of this study was to evaluate the difference in the time to postintubation sedation between patients receiving etomidate and either succinylcholine or rocuronium in the prehospital setting. This study suggests... read more

Vitamin Treatment For Sepsis Fails In Large Trial

Vitamin Treatment For Sepsis Fails In Large Trial

Hope for an effective and inexpensive treatment for the deadly condition sepsis has dimmed following results of a major new study. Researchers had hoped that a simple treatment involving infusions of vitamin C, vitamin... read more

Effect of Stress Ulcer Prophylaxis on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation

Effect of Stress Ulcer Prophylaxis on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation

Among ICU patients requiring mechanical ventilation, a strategy of stress ulcer prophylaxis with use of proton pump inhibitors vs histamine-2 receptor blockers resulted in hospital mortality rates of 18.3% vs 17.5%, respectively,... read more

Study Suggests Benefits of Vitamin C for Severe Sepsis

Study Suggests Benefits of Vitamin C for Severe Sepsis

More than 1.7 million Americans develop sepsis every year and incidence of the condition is on the rise. In severe cases, widespread inflammation leads to multiorgan failure and death. Results of a new study hold... read more

Ventilator Management: Advanced Concepts In Critical Care

Ventilator Management: Advanced Concepts In Critical Care

Mechanical ventilation is a broad subject that encompasses many factors that must be considered while providing overall resuscitation. It is not as easy as just entering in a rate and tidal volume and pushing start. Critical... read more

Admissions Trends, Resource Use, and Risk-adjusted Hospital Mortality for Elderly Patients Admitted to ICUs

Admissions Trends, Resource Use, and Risk-adjusted Hospital Mortality for Elderly Patients Admitted to ICUs

Over the past two decades, elderly patients have been more commonly admitted to ICU than can be explained solely by the demographic shift. Importantly, as with the wider population, outcomes in elderly patients admitted to... read more

Early Psychological Screening of ICU Survivors

Early Psychological Screening of ICU Survivors

Symptoms of post-traumatic stress, anxiety and depression assessed 1 week after ICU stay correlate with 3-month psychological outcome. The HADS and PTSS-10 may be useful aids to identify ICU survivors at high risk for... read more

Lower Glucose Targets Show Improved Mortality in Cardiac Patients

Lower Glucose Targets Show Improved Mortality in Cardiac Patients

Tighter glucose control while minimizing the risk of severe hypoglycemia is associated with lower mortality among critically ill cardiac patents, new research suggests. Researchers reported in CHEST on the outcomes of... read more

Critical Care Opioids Impact in the 21st Century

Critical Care Opioids Impact in the 21st Century

Critical Care is impacted by opioids in multiple ways. Not only do they form the backbone of managing pain and sedation in the intensive care unit (ICU), the burgeoning opioid epidemic also feeds into opioid-related ICU admissions.... read more

Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus Aureus Bacteremia

Delay in Antibiotic Administration Is Associated With Mortality Among Septic Shock Patients With Staphylococcus Aureus Bacteremia

The results of this study further support the importance of prompt appropriate antibiotic administration for patients with septic shock. Physicians should consider acting quickly to administer antibiotics with S. aureus... read more

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Microcirculation is severely impaired in patients with refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO). Inability to rapidly restore microcirculation during the first... read more

Modified Version of the ACC’s low-dose 4PCC Warfarin Reversal Option Achieves Similar Outcomes for Lowering INR

Modified Version of the ACC’s low-dose 4PCC Warfarin Reversal Option Achieves Similar Outcomes for Lowering INR

A modified version of the American College of Cardiology (ACC) low-dose four factor prothrombin complex concentrate (4PCC) option for warfarin reversal achieves similar outcomes for lowering International Normalized Ratio... read more

ICU Bouncebacks Associated with Worse Outcomes

ICU Bouncebacks Associated with Worse Outcomes

ICU Bouncebacks (ICUBBs) are associated with worse outcomes and are disproportionately burdened by respiratory complications. These findings emphasize the importance of the TQIP Collaborative in identifying statewide... read more