Tag: treatment
Percussion Pacing – An Almost Forgotten Procedure for Hemodynamically Unstable Bradycardias?
More than 80 years after its first description by Eduard Schott, percussion (fist) pacing remains a little known procedure even though it represents an instantly available and easy to perform treatment for temporary emergency... read more
Effect of Bradykinin Receptor Antagonism on ACE Inhibitor-associated Angioedema
This study compared the effect of placebo versus the bradykinin B2 receptor antagonist icatibant on symptoms of ACE inhibitor–associated angioedema in a mixed race population of patients. The study does not support the... read more
Buprenorphine-Precipitated Opioid Withdrawal in the ED
Buprenorphine-precipitated opioid withdrawal is seen in patients physically dependent on opioids who have recently taken full-agonist opioids and are then administered buprenorphine. Patients with severe withdrawal commonly... read more
Clinical, Biological and Molecular Aspects of COVID-19
The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just eight months. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the... read more
Balanced Crystalloids Probably Reduce Mortality in the Critically-Ill
As remarked by the authors of the recent PLUS trial, a systematic review and meta-analysis of randomized controlled trials comparing balanced resuscitation fluid to 0.9% saline was reported in the New England Journal of Medicine... read more
Lung Ultrasonography Beyond the Diagnosis of Pediatrics Pneumonia
Pneumonia is a prevalent disease with considerable morbidity and mortality among the pediatric population. Early diagnosis and swift commencement of the correct treatment are vital for a favorable clinical outcome. Along... read more
Pediatric Pneumonia Research Priorities in the Context of COVID-19
Operational research on health system capacities, and evaluating optimized delivery of existing treatments, diagnostics and case management approaches are needed. This list should act as a catalyst for collaborative research,... read more
Patients’ Perspectives on Point-of-Care Diagnostics in Acute COPD Exacerbations
Patients' perspectives showed that point-of-care diagnostics and treatment of acute COPD in exacerbation was considered a qualitative offer by the patients and their relatives. At the same time, it was crucial that the emergency... read more
Information Transfer as a Strategy to Improve Safety in ICU
In an Intensive Care Unit (ICU), we attend people with a wide range of pathologies. All the information obtained from monitoring our critical patients, diagnostic and therapeutic techniques, responses to treatments, action... read more
Effect of Intra-arrest Transport, ECPR, and Treatment on Functional Neurologic Outcome
Among patients with refractory out-of-hospital cardiac arrest, the bundle of early intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and invasive assessment and treatment did not significantly improve... read more
Cancer Treatments Not Associated with Inferior COVID-19 Outcomes
The findings of this study of patients with active cancer suggest that recent systemic anticancer treatments (SACTs) is not associated with inferior outcomes from COVID-19 infection. This has relevance for the care of... read more
Deconstructing the Way We Use Pulmonary Function Test Race-Based Adjustments
Race is a social construct. It is used in medical diagnostic algorithms to adjust the readout for spirometry and other diagnostic tests. The authors review historic evidence about the origins of race adjustment in spirometry,... read more
Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19
At approximately 4 months after acute illness, cognitive dysfunction, emotional distress, and functional decline were common among a diverse clinical sample of COVID-19 survivors varying in acute illness severity. Patients... read more
Leriche Syndrome Diagnosed Due to Polytrauma
In this case, conservative therapy was initially chosen for Leriche syndrome. However, the complex factors in the acute phase of trauma led to development of hemorrhagic necrosis, requiring amputation of the lower extremity.... read more
Hemodynamic Status During Endovascular Stroke Treatment
In our protocol-based setting, intraprocedural pre-recanalization BP reductions during endovascular therapy were not associated with functional outcome. However, higher intraprocedural pre-recanalization SBP and MAP were... read more
Cluster ICU Treatment Strategies for TBI by Hospital Treatment Preferences?
Although correlations between treatment policies within domains were found, the failure to cluster hospitals indicates that a specific treatment choice within a domain is not a proxy for other treatment choices within or... read more
Inflammatory and Immunosuppressive Responses to COVID-19 and Bacterial Sepsis
Bacterial sepsis patients had early, severe inflammation, profound immune suppression, and life-threatening organ dysfunction that resolved over time; SARS-CoV-2 patients had less severe early inflammation and organ dysfunction... read more
ARDS Subphenotypes Validation and Utility Identified by Machine-learning Models
Classifier models using clinical variables alone can accurately assign ARDS subphenotypes in observational cohorts. Application of these models can provide valuable prognostic information and could inform management strategies... read more
Coupled Plasma Filtration and Adsorption for Septic Shock Treatment
Early deaths are likely related to the ongoing CPFA treatment, for reasons that if identified could allow some deaths to be prevented. We hypothesize a connection to hemodynamic instability consequent on renal replacement... read more
ICU Quick Drug Guide
Offering essential, evidence-based practice guidelines specifically for the critical care setting, ICU Quick Drug Guide contains up-to-date information in a quick-access format. This portable handbook provides fast, accurate... read more
The Reemergence of Ketamine for Treatment in Critically Ill Adults
Ketamine has suggested potential benefit in several disease states impacting critically ill patients including pain, alcohol withdrawal syndrome, status epilepticus, and acute agitation. Further supporting evidence is needed... read more
COVID-19 Vaccine: Safety and Efficacy
Two doses of SCB-2019 vaccine plus CpG and alum provides notable protection against the entire severity spectrum of COVID-19 caused by circulating SAR-CoV-2 viruses, including the predominating delta variant. This ongoing... read more
