Optimal Follow-up After Acute Pulmonary Embolism

Optimal Follow-up After Acute Pulmonary Embolism

This position paper provides a comprehensive guide for optimal follow-up of patients with acute pulmonary embolism (PE), covering multiple relevant aspects of patient counselling. It serves as a practical guide to treating... read more

Outcomes of Catheter-Related Arterial and Venous Thrombosis After Enoxaparin Therapy in Neonates and Infants With Congenital Heart Disease

Outcomes of Catheter-Related Arterial and Venous Thrombosis After Enoxaparin Therapy in Neonates and Infants With Congenital Heart Disease

A high proportion of vascular catheter-related thrombi identified in infants with congenital heart disease resolve with enoxaparin treatment. In all patients with thrombosis, arterial versus venous thrombosis is associated... read more

Intravenous Push Levetiracetam Safety in a Neuro-Spine ICU

Intravenous Push Levetiracetam Safety in a Neuro-Spine ICU

Administration of levetiracetam doses up to 2000 mg via IVP is a safe method of administration that results in a reduction of time to medication administration and a reduction of benzodiazepine use. Of the 2,055 hospital-wide... read more

Organophosphorus Compounds and Oximes

Organophosphorus Compounds and Oximes

Organophosphorus (OP) pesticides and nerve agents still pose a threat to the population. Treatment of OP poisoning is an ongoing challenge and burden for medical services. Standard drug treatment consists of atropine and... read more

Procalcitonin-guided Antibiotic Treatment Effect on Mortality in Acute Respiratory Infections

Procalcitonin-guided Antibiotic Treatment Effect on Mortality in Acute Respiratory Infections

Use of procalcitonin to guide antibiotic treatment in patients with acute respiratory infections reduces antibiotic exposure and side-effects, and improves survival. Widespread implementation of procalcitonin protocols... read more

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

Identification of Biomarkers, New Treatments, and Vaccines for COVID-19

The novel coronavirus 2019 (COVID-19) has caused a serious global pandemic in just one year. Nearly every country and territory in the world has been affected by the virus. The virulence and infection rate of the virus are... read more

Rapidly Progressive Brain Atrophy in Septic ICU Patients

Rapidly Progressive Brain Atrophy in Septic ICU Patients

Many ICU patients with severe sepsis who developed prolonged mental status changes and neurological sequelae showed signs of brain atrophy. Patients with rapidly progressive brain atrophy were more likely to have required... read more

Oxygenation Responses Mechanisms to Proning and Recruitment in COVID-19 Pneumonia

Oxygenation Responses Mechanisms to Proning and Recruitment in COVID-19 Pneumonia

In unresolving COVID-19 pneumonia, the respiratory mechanics and the gas-exchange response to prone positioning and recruitment largely depend on the following two factors: perfusion dysregulation and the amount of consolidated... read more

Coronavirus Disease 2019 (COVID-19): Epidemiology, Pathogenesis, Diagnosis, and Therapeutics

Coronavirus Disease 2019 (COVID-19): Epidemiology, Pathogenesis, Diagnosis, and Therapeutics

This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing... read more

WHO Issues Guidelines on the Treatment of Children with MIS Associated with COVID-19

WHO Issues Guidelines on the Treatment of Children with MIS Associated with COVID-19

WHO issued updated guidelines on the management of multisystem inflammatory syndrome (MIS) in children associated with COVID-19 (MIS-C). MIS-C is a rare but serious condition where children with COVID-19 develop inflammation... read more

High Flow Nasal Oxygen: A Rising Star Waiting To Be Discovered

High Flow Nasal Oxygen: A Rising Star Waiting To Be Discovered

High flow nasal oxygen therapy (HFNO2) is gaining popularity of late and rapidly recognised as new oxygen therapy in the treatment of respiratory failure, and the fame exploded exponentially after the COVID-19 pandemic. HFNO2... read more

Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant

Inhaled Pulmonary Vasodilator Therapy in Adult Lung Transplant

Among patients undergoing LT, use of iEPO was associated with similar risks for PGD-3 development and other postoperative outcomes compared with the use of iNO. A total of 201 randomized patients met eligibility criteria... read more

Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest

Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest

Among patients with in-hospital cardiac arrest, administration of vasopressin and methylprednisolone, compared with placebo, significantly increased the likelihood of return of spontaneous circulation. However, there is uncertainty... read more

Ivermectin Not the Crisis It’s Claimed to Be

Ivermectin Not the Crisis It’s Claimed to Be

I can't remember any time when the U.S. Food and Drug Administration had to resort to the faux-folksy mode of expression to try to get its point across. We live in strange times. The FDA was responding, of course, to the... read more