Tag: treatment
Efficacy of Inhaled Ciclesonide for Outpatient Treatment with Symptomatic COVID-19
The results of this randomized clinical trial demonstrated that ciclesonide did not achieve the primary efficacy end point of reduced time to alleviation of all COVID-19–related symptoms. A total of 413 participants... read more
Immunological Dysfunction Persists for 8 months Following Initial Mild-to-Moderate COVID-19 Infection
A proportion of patients surviving acute coronavirus disease 2019 (COVID-19) infection develop post-acute COVID syndrome (long COVID (LC)) lasting longer than 12 weeks. Here, we studied individuals with LC compared to... read more
Effect of Early Fluvoxamine Treatment Among COVID-19 Patients
Treatment with fluvoxamine (100 mg twice daily for 10 days) among high-risk outpatients with early diagnosed COVID-19 reduced the need for hospitalisation defined as retention in a COVID-19 emergency setting or transfer to... read more
Early Remdesivir to Prevent Progression to Severe COVID-19 in Outpatients
Among nonhospitalized patients who were at high risk for Covid-19 progression, a 3-day course of remdesivir had an acceptable safety profile and resulted in an 87% lower risk of hospitalization or death than placebo. A... read more
ECMO. Extracorporeal Membrane Oxygenation
Extracorporeal membrane oxygenation (ECMO), is a rapidly developing technology for supporting or even replacing heart and/or lung functions for days or weeks, giving the time for recovery, other therapeutic interventions... read more
Bringing Biological ARDS Phenotypes to the Bedside with Machine-learning-based Classifiers
The identification of distinct phenotypes within heterogeneous disease states is a key component of personalised medicine, enabling enrichment of clinical trials, better prognostication, and delivery of tailored treatments... read more
Anticoagulation in COVID-19
Thrombotic complications (arterial and venous) are common in patients admitted to hospital with COVID-19 and are an independent predictor of poor outcome. Microvascular thrombi also contribute to organ dysfunction, including... read more
A New Acronym to Select Eligible Patients for ECPR
Rhythm check three - A2BCDE3! - A new acronym to select eligible patients for extracorporeal cardiopulmonary resuscitation (eCPR) Extracorporeal cardiopulmonary resuscitation (eCPR) is an ultra-invasive approach for the... read more
Loading and Increasing Vancomycin Dose Frequency Not Advantageous for Gram-Positive Sepsis in Infants
The efficacy of a vancomycin loading dose with more frequent dosing and shorter duration of treatment was comparable to standard dosing regimens for gram-positive sepsis in infants but with heightened risk for impaired hearing,... read more
Novel Antibiotics Efficacy for Sepsis ICU Patients
Restricting severely ill patients access to new broad-spectrum empirical drugs is not the answer. Rather there should be a focus on identifying host response to infection to differentiate between colonization or contamination... read more
Continuous RRT in Critically Ill Children
The survival rate of patients received continuous renal-replacement therapy (RRT) treatment in our center has improved over past 10 years, and some changes have taken place during these periods. Among them, early initiation... read more
The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia
This book is a practical manual for anti-COVID-19. It is not only with the reference to the result of modern medical science, patients' situation, but also take the deployment of medical resources into consideration. Content... read more
COVID-19: Limitation of Life-sustaining Treatment and Patient Involvement in Decision-making
Life-sustaining treatment limitation decisions were made for 18% of a COVID-19 patient cohort. Hereof, more than a third of the decisions had been made before hospital admission. Many records lacked information on patient... read more
Interim-analysis of the COVID-19 Patients Treated with the Seraph 100 Microbind Affinity Filter Registry
The treatment of COVID-19 patients with Seraph®100 is well tolerated and the circuit failure rate was lower than previously reported for KRT in COVID-19 patients. Mortality corelated with late initiation of Seraph treatment... read more
